Results 171 to 180 of about 12,878 (216)

Mechanotransduction and cell fate: from molecular sensors to multicellular self-organization. [PDF]

open access: yesFront Cell Dev Biol
Estrada Elorza MDC   +6 more
europepmc   +1 more source

Decoding the Histomorphological and Multi-Omic Characteristics of Melanotic Schwannoma. [PDF]

open access: yesCurr Med Sci
Jiang Y   +9 more
europepmc   +1 more source

TRPA1

2014
The transient receptor potential ankyrin subtype 1 protein (TRPA1) is a nonselective cation channel permeable to Ca(2+), Na(+), and K(+). TRPA1 is a promiscuous chemical nocisensor that is also involved in noxious cold and mechanical sensation. It is present in a subpopulation of Aδ- and C-fiber nociceptive sensory neurons as well as in other sensory ...
Peter M, Zygmunt, Edward D, Högestätt
openaire   +4 more sources

TRPA1

2007
The TRPA1 protein has up to 18 N-terminal and presumed cytoplasmic ankyrin repeats followed by the six membrane spanning and single pore-loop domains characteristic of all TRPs. In mice, TRPA1 is almost exclusively expressed in nociceptive neurons of peripheral ganglia and in all the mechanosensory epithelia of inner ear.
J, García-Añoveros, K, Nagata
openaire   +2 more sources

MechanoTRPs and TRPA1

2007
Genetic and molecular searches in animals identify two families of ion channels used by specialized mechanosensory cells. These are the degenerin/epithelial Na+ channels (Deg/ENaCs) and transient receptor potential (TRP) channels. Some of these channels open in response to mechanical forces and/or mediate cellular responses to mechanical stimulation ...
Andrew J, Castiglioni   +1 more
openaire   +2 more sources

TRPA1 receptors in cough

Pulmonary Pharmacology & Therapeutics, 2011
In the early 1990's ion channels of the Transient Receptor Potential (TRP) class were implicated in the afferent sensory loop of the cough reflex and in the heightened cough sensitivity seen in disease. Agonists of the TRPV1 capsaicin receptor such as vanilloids and protons were demonstrated to be amongst the most potent chemical stimuli which cause ...
Grace, Megan S., Belvisi, Maria G.
openaire   +3 more sources

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