Results 181 to 190 of about 12,878 (216)

Sanguinarine is an agonist of TRPA1 channel

Biochemical and Biophysical Research Communications, 2021
Sanguinarine, a benzyl isoquinoline alkaloid extracted from the root of Papaveraceae plants, shows extensive pharmacological activities including anti-microbial, anti-trypanosoma, anti-tumor, anti-platelet, anti-hypertensive effects, as well as inhibition of osteoclast formation.
Hao Chi, Xian Zhang, Xueqin Chen, Sui Fang, Qiang Ding, Zhaobing Gao   +5 more
openaire   +2 more sources

TRPA1 modulators in preclinical development

Expert Opinion on Therapeutic Patents, 2009
Transient receptor potential ankyrin 1 (TRPA1) has been revealed as a pivotal molecular entity in sensory biology, especially as a sensor of chemical irritants present in foods, atmospheric pollutants and neurotoxic compounds. In addition, this channel appears responsible for detecting physical signals such as noxious cold and mechanical forces.There ...
Viana, Félix, Ferrer-Montiel, Antonio
openaire   +3 more sources

TRPA1-Kationenkanäle

2019
Der „Transient Receptor Potential Ankyrin 1“ (TRPA1) Kanal zeichnet sich als Mitglied der TRP-Familie durch eine größere Zahl an sog. „Ankyrin-Repeats“ im Aminoterminus aus. Ansonsten besitzt er wie alle anderen TRP-Kanäle intrazelluläre Termini und sechs Transmembrandomänen mit einem Poren-bildenden Bereich zwischen der Domäne fünf und sechs.
openaire   +1 more source

TRPA1

2006
Sven-Eric Jordt, Marilia Guimaraes
openaire   +2 more sources

TRPA1-mediated nociception

Neuroscience, 2008
L, Fischer, C H, Tambeli, C A, Parada
openaire   +2 more sources

Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance

Cancer Cell, 2018
Yasuo Mori, Daniel Stover, Gordon Mills   +2 more
exaly  

Evidence for the pathophysiological relevance of TRPA1 receptors in the cardiovascular system in vivo

Cardiovascular Research, 2010
David Andersson, Stuart John Bevan
exaly  

TRPA1‐mediated responses in trigeminal sensory neurons: interaction between TRPA1 and TRPV1

European Journal of Neuroscience, 2009
Armen Akopian, Kenneth Hargreaves, Margaux M Salas   +2 more
exaly  

TRPA1 inhibition ameliorates pressure overload-induced cardiac hypertrophy and fibrosis in mice

EBioMedicine, 2018
Jun Wan
exaly  

TRPA1 regulates macrophages phenotype plasticity and atherosclerosis progression

Atherosclerosis, 2020
Yongjian Yang, Ken Chen
exaly