Elektrophysiologische Charakterisierung des klassischen TRP-Kanals TRPC5
Klassische TRP-Kanäle (TRPC) sind Ca(2+)-permeable, unselektive Kationenkanäle, die durch PLC-abhängige Signalwege intrazellulär aktiviert werden. Obwohl die ersten Mitglieder dieser Subfamilie bereits vor über 15 Jahren kloniert wurden, sind sie auf funktioneller Ebene bisher nur unvollständig untersucht. Das Ziel dieser
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Structural identification of riluzole-binding site on human TRPC5
Yaxiong Yang, Miao Wei, Lei Chen
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Transient receptor potential canonical 3/5 attenuate endothelial damage-induced neointima formation without affecting endothelial cell proliferation. [PDF]
Zeng W, Liu B, Yang L, Guo R.
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Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies [PDF]
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Tricyclic antidepressants dose-dependently modulate the biphasic activity of the TRPC5 channel through opioid receptors. [PDF]
Jeong B, Chung JY, Jun JY, Hong C.
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Tooth Pulp Afferents and Transient Receptor Potential (TRP) Ion Channels as Key Regulators of Pulp Homeostasis, Inflammation, and Pain. [PDF]
Chung MK, Raman S, Szallasi A.
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Role of transient receptor potential (TRP) channels in osteoarthritis: a comprehensive review. [PDF]
Qiao P +9 more
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Lipid Regulation of Mechanosensitive Ion Channels. [PDF]
Cai Y, Bauer C, Shi J.
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Transferring intercellular signals and traits between cancer cells: extracellular vesicles as “homing pigeons” [PDF]
core +1 more source
Molecular evolution of TRPC4 regulatory sequences supports a role in mammalian thermoregulatory adaptation. [PDF]
Cornman RS.
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