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Aldose reductase deficiency protects the retinal neurons in a mouse model of retinopathy of prematurity [PDF]

, 2012
Poster Presentation: P64PURPOSE: Retinopathy of prematurity (ROP) is a common retinal disease occurred in premature babies. It is found to be related to oxidative stress while dysfunction of the neural retina has also been documented.
Chung, SK, Fu, Z, Li, SY, Lo, ACY, Wong, D +4 more
core

Identifizierung und Charakterisierung neuer TRPC5-Kanalmodulatoren

, 2019
Der TRPC5-Ionenkanal gehört zur Familie der transienten Rezeptorpotenzial-Kanäle und wird vorwiegend im Zentralnervensystem exprimiert. Um die Funktionsweise des Kanals besser zu verstehen, wurden in dieser Arbeit im Rahmen eines Wirkstoffscreenings die folgenden Verbindungen als neue Ionenkanalmodulatoren identifiziert und charakterisiert: Mit einer ...
openaire +1 more source

A key role of TRPC channels in the regulation of electromechanical activity of the developing heart [PDF]

, 2017
Aims It is well established that dysfunction of voltage-dependent ion channels results in arrhythmias and conduction disturbances in the foetal and adult heart.
Raddatz, Eric, Robin, Elodie, Sabourin, Jessica +2 more
core

Claudin and transmembrane receptor protein gene expressions are reversely correlated in peritumoral brain edema

Cancer Medicine
Introduction Peritumoral brain edema (PTBE) has been widely reported with many brain tumors, especially with glioma. Since the blood–brain barrier (BBB) is essential for maintaining minimal permeability, any alteration in the interaction of BBB ...
Anwar Abuelrub +3 more
doaj +1 more source

Ideal efficacy photoswitching for chromocontrol of TRPC4/5 channel functions in live tissues. [PDF]