Results 171 to 180 of about 5,561 (208)

TRP channels in mammalian hearing loss. [PDF]

open access: yesFront Mol Neurosci
Zhang Z, Wang B.
europepmc   +1 more source

The Impact of a Quinone Scaffold on Thermo-TRPs Modulation by Dimethylheptyl Phytocannabinoids. [PDF]

open access: yesInt J Mol Sci
Schiano Moriello A   +8 more
europepmc   +1 more source

Carnosic acid in topical rosemary extract enhances skin repair via TRPA1 activation. [PDF]

open access: yesJCI Insight
Rapp E   +5 more
europepmc   +1 more source

TRPV3 Ion Channel: From Gene to Pharmacology

open access: yesInternational Journal of Molecular Sciences, 2023
Transient receptor potential vanilloid subtype 3 (TRPV3) is an ion channel with a sensory function that is most abundantly expressed in keratinocytes and peripheral neurons. TRPV3 plays a role in Ca2+ homeostasis due to non-selective ionic conductivity and participates in signaling pathways associated with itch, dermatitis, hair growth, and skin ...
Александр Калиновский   +2 more
exaly   +3 more sources
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TRPV3 endogenously expressed in murine colonic epithelial cells is inhibited by the novel TRPV3 blocker 26E01

Cell Calcium, 2020
TRPV3 is a Ca2+-permeable cation channel, prominently expressed by keratinocytes where it contributes to maintaining the skin barrier, skin regeneration, and keratinocyte differentiation. However, much less is known about its physiological function in other tissues and there is still a need for identifying novel and efficient TRPV3 channel blockers. By
Carina Glas   +2 more
exaly   +3 more sources

Analgesic Potential of TRPV3 Antagonists

Current Topics in Medicinal Chemistry, 2011
The vanilloid subfamily of transient receptor potential (TRPV) ion channels serves critical functions in sensory signaling in specialized cells and intact organisms ranging from yeast to primates. As thermosensors, chemosensors, and/or mechanosensors, these channels monitor the local environment and integrate and respond to multiple stimuli ...
Regina M, Reilly, Philip R, Kym
openaire   +2 more sources

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