Results 71 to 80 of about 456,372 (322)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Renaming as a factor of successful marketing communication

Неофилология
INTRODUCTION. In 2022, due to the political situation in the world, many foreign brands were forced to leave the Russian market. After some time, some of them returned, undergoing renaming – changing their trade name.
A. V. Zavadskaya
doaj   +1 more source

NLO Renormalization in the Hamiltonian Truncation

, 2017
Hamiltonian Truncation (a.k.a. Truncated Spectrum Approach) is a numerical technique for solving strongly coupled QFTs, in which the full Hilbert space is truncated to a finite-dimensional low-energy subspace.
Elias-Miro, Joan, Rychkov, Slava, Vitale, Lorenzo G.   +2 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Language form compression in modern Russian speech

Russian Language Studies
Compressive word formation results from the active tendency to save speech effort and, accordingly, to save linguistic means, which makes its research relevant.
Elena M. Markova
doaj   +1 more source

The Bounded Laplace Mechanism in Differential Privacy

The Journal of Privacy and Confidentiality, 2019
The Laplace mechanism is the workhorse of differential privacy, applied to many instances where numerical data is processed. However, the Laplace mechanism can return semantically impossible values, such as negative counts, due to its infinite support ...
Naoise Holohan, Spiros Antonatos, Stefano Braghin, Pól Mac Aonghusa   +3 more
doaj   +1 more source

W-superalgebras as truncation of super-Yangians

, 2002
We show that some finite W-superalgebras based on gl(M|N) are truncation of the super-Yangian Y(gl(M|N)). In the same way, we prove that finite W-superalgebras based on osp(M|2n) are truncation of the twisted super-Yangians Y(gl(M|2n))^{+}.
Arnaudon D, Bernard D, Briot C, Briot C, C Briot, Drinfeld V G, Drinfeld V G, E Ragoucy, Faddeev L D, Frappat L, Frappat L, Gerstenhaber M, Mintchev M, Molev A, Molev A I, Nazarov M L, Olshanski G I, Ragoucy E, Zhang R B   +18 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

On two aspects of the Painleve analysis

, 2013
We use the Calogero equation to illustrate the following two aspects of the Painleve analysis of nonlinear PDEs. First, if a nonlinear equation passes the Painleve test for integrability, the singular expansions of its solutions around characteristic ...
Sakovich, Sergei
core   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source