Results 81 to 90 of about 227,718 (306)

Beyond Silence, Towards Refusal: The Epistemic Possibilities of #MeToo [PDF]

open access: yes, 2019
There are many ways to understand the meanings of the #MeToo movement. Analyses of its significance have proliferated in popular media; some academic analyses have also recently appeared. Commentary on the philosophical and epistemic significance of the #
Miller, Sarah
core  

Deconstructing Section 11: Public Offering Liability in a Continuous Disclosure Environment [PDF]

open access: yes, 2000
There can be no successful reform of the system of capital-raising regulation in the US without rethinking the liability regime. Reform is long overdue and can readily be accomplished in a way that does not unnecessarily compromise investor ...
Langevoort, Donald C.
core   +3 more sources

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

The Work of Art and Truth of Being as Historical : Reading Being and Time, The Origin of the Work of Art, and the Turn (Kehre) in Heidegger’s Philosophy of the 1930s [PDF]

open access: yes, 2009
Reading Heidegger’s Being and Time, “The Origin of the Work of Art,” and the 1934-35 lecture courses Hölderlin’s Hymns“Germania” and “The Rhine,” the aim of this essay is twofold. First, the essay attempts to elucidate the manner in which the work of art
Magrini, James
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Interviewing suspects: examining the association between skills, questioning, evidence disclosure, and interview outcomes [PDF]

open access: yes, 2015
The interviewing of suspects is an important element in the investigation of crime. However, studies concerning actual performance of investigators when undertaking such interviews remain sparse. Nevertheless, in England and Wales, since the introduction
Baldwin J.   +17 more
core   +3 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Truth telling for patients with esophageal squamous cell carcinoma in Henan, China

open access: yesCancer Biology & Medicine, 2017
Objective : This study aims to investigate the truth-telling status and the relevant factors of esophageal squamous cell carcinoma (ESCC) patients in Henan, China.Methods : A cross-sectional study from April to June 2015 using questionnaires was given to
Lian-Qun Zhang   +16 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The Palliative Care Clinical Evaluation Exercise

open access: yesMedEdPORTAL, 2006
The purpose of this resource is to evaluate the feasibility and perceived educational value among internal medicine interns as related to the Palliative Care Clinical Exercise (CEX), a new experience-based intervention to teach communication skills in ...
Paul Han
doaj   +1 more source

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