Results 111 to 120 of about 167,118 (269)

Antigenic variation in the African trypanosome: molecular mechanisms and phenotypic complexity [PDF]

open access: yes, 2009
Antigenic variation is an immune evasion strategy that has evolved in viral, bacterial and protistan pathogens. In the African trypanosome this involves stochastic switches in the composition of a variant surface glycoprotein (VSG) coat, using a massive ...
Marcello, Lucio   +2 more
core   +1 more source

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

open access: yesArchiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi   +17 more
wiley   +1 more source

Through the dark continent: African trypanosome development in the tsetse fly [PDF]

open access: yes, 2013
African trypanosomes are unicellular flagellated parasites causing trypanosomiases in Africa, a group of severe diseases also known as sleeping sickness in human and nagana in cattle.
Rotureau, Brice, Van Den Abbeele, Jan
core   +4 more sources

Immunoelectrophoretic comparison of Trypanosoma vespertilionis and Trypanosoma cruzi.

open access: yesRevista de biologia tropical, 1971
Immunoelectrophoretically, T. vespertilionis showed five of seven antigenic fractions found with T. cruzi antigen, indicating a close similarity between these two species. An antigen made of L. braziliensis promastigotes did not give any precipitation band against T. cruzi antiserum.
Bice, David E., Zeledón, Rodrigo
openaire   +2 more sources

Phytochemical and Biological Evaluation of Leaves, Stems, and Roots of Schinus weinmanniifolia Mart. Ex Engl.

open access: yesChemistry &Biodiversity, Volume 23, Issue 3, March 2026.
Ethanolic extracts from leaves, stems, and roots of Schinus weinmanniifolia Mart. ex Engl. were evaluated for phytochemical composition and biological activities. The extracts exhibited antioxidant, photoprotective, and antimicrobial activity, without hemolytic effects or cytotoxicity at active concentrations. Syringic acid, epicatechin, and rutin were
João Andrade   +14 more
wiley   +1 more source

Tracking autophagy during proliferation and differentiation of trypanosoma brucei [PDF]

open access: yes, 2014
Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Coombs, Graham H.   +3 more
core   +3 more sources

Helminths as architects of trained tolerance: implications for human health

open access: yesClinical &Translational Immunology, Volume 15, Issue 3, 2026.
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz   +2 more
wiley   +1 more source

First Step Towards the Humanisation of Protein N‐Glycosylation in Chlamydomonas reinhardtii Through Heterologous Expression of α(1,2)‐Mannosidases

open access: yes
Plant Biotechnology Journal, Volume 24, Issue 4, Page 2698-2700, April 2026.
C. Plasson   +4 more
wiley   +1 more source

Oxidative costs of migration: infections as an added burden

open access: yesJournal of Avian Biology, Volume 2026, Issue 2, March 2026.
There is increasing evidence that over‐production of reactive species (RS) constitutes a significant physiological cost for migrating birds. The current view entails that RS during migration originate primarily from increased metabolic activity associated with prolonged flights and refueling.
Michael Tobler   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy