Results 141 to 150 of about 101,216 (253)
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf +10 more
wiley +1 more source
Epidemiología de la enfermedad de Chagas, Departamento General Paz, Argentina
OBJETIVO: El objetivo del presente trabajo fue investigar la colonización por triatominos en ambientes domésticos y peridomésticos y evaluar la seroprevalencia de infectados chagásicos en localidades rurales.
Elena B Oscherov +5 more
doaj
El objetivo de este trabajo fue evaluar parasitológica y serológicamente la presencia de Anaplasma spp., Trypanosoma spp. y Babesia spp. En venados de cola blanca (Odocoileus virginianus) en una región del Edo.
Adriana Silva Iturriza +4 more
doaj
Abstract Infections by Pseudomonas aeruginosa are a major cause of severe morbidity and mortality in immunocompromised patients and people with cystic fibrosis, largely due to the pathogen's ability to resist antibiotic treatment and to deploy multiple virulence strategies that promote persistence in the host.
Gianluca Pistoia +12 more
wiley +1 more source
Editorial: Disruptive technologies for the study of host-pathogen interactions
Juan F. Quintana +6 more
doaj +1 more source
We evaluated the performance of an indirect immunofluorescence (IIF) assay for detecting anti‐Trypanosoma cruzi IgG in dogs using four chimeric IBMP antigens and latent class analysis. The IIF assay showed suboptimal sensitivity and overall accuracy compared to ELISA and LCA‐based methods.
Ângelo Antônio Oliveira Silva +13 more
wiley +1 more source
ABSTRACT Agricultural by‐products are increasingly valorized as food ingredients within circular food systems. However, their safety cannot be directly inferred from their corresponding primary commodities. Moreover, agricultural by‐products serve as secondary risk matrices by acting as reservoirs or accumulation points for microbiological hazards ...
Vinothini Boopathi +6 more
wiley +1 more source
An integrated computational‐experimental workflow enabled CRK12‐guided hit discovery against Trypanosoma brucei under limited structural and ligand data. The workflow of virtual screening and anti‐T. brucei bioassays identified 4 hit compounds, including three low‐micromolar leads (IC50 = 1.47, 0.81, and 1.33 μM). ABSTRACT Human African trypanosomiasis
Qin Li +11 more
wiley +1 more source
ABSTRACT Cells exhibit a wide range of behaviors due to their diverse molecular systems, which have been established through the molecular evolution of individual species. Protein families generated through gene duplications may be involved in this process. The actin cytoskeleton is no exception.
Miku Kagawa +8 more
wiley +1 more source
Galactose starvation in a bloodstream form Trypanosoma brucei UDP-glucose 4'-epimerase conditional null mutant [PDF]
Galactose metabolism is essential for the survival of Trypanosoma brucei, the etiological agent of African sleeping sickness. T. brucei hexose transporters are unable to transport galactose, which is instead obtained through the epimerization of UDP ...
Turnock, Daniel C. +2 more
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