Results 141 to 150 of about 101,216 (253)

Quaternary structures of Streptococcus pneumoniae nucleoside diphosphate kinase: From hexamers to supramolecular assemblies

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf   +10 more
wiley   +1 more source

Epidemiología de la enfermedad de Chagas, Departamento General Paz, Argentina

open access: yesRevista de Saúde Pública
OBJETIVO: El objetivo del presente trabajo fue investigar la colonización por triatominos en ambientes domésticos y peridomésticos y evaluar la seroprevalencia de infectados chagásicos en localidades rurales.
Elena B Oscherov   +5 more
doaj  

Evaluación parasitológica y serológica de infecciones hemotrópicas en venados de cola blanca (Odocoileus virginianus) en Venezuela.

open access: yesRevista Científica, 2013
El objetivo de este trabajo fue evaluar parasitológica y serológicamente la presencia de Anaplasma spp., Trypanosoma spp. y Babesia spp. En venados de cola blanca (Odocoileus virginianus) en una región del Edo.
Adriana Silva Iturriza   +4 more
doaj  

Structural and functional insights into Pseudomonas aeruginosa ApaH, a diadenosine tetraphosphatase crucial for bacterial virulence

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Infections by Pseudomonas aeruginosa are a major cause of severe morbidity and mortality in immunocompromised patients and people with cystic fibrosis, largely due to the pathogen's ability to resist antibiotic treatment and to deploy multiple virulence strategies that promote persistence in the host.
Gianluca Pistoia   +12 more
wiley   +1 more source

Editorial: Disruptive technologies for the study of host-pathogen interactions

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Juan F. Quintana   +6 more
doaj   +1 more source

Assessment of the Performance of Indirect Immunofluorescence Assay for Chagas Disease in Dogs Using a Reference Panel of Four Chimeric Proteins

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
We evaluated the performance of an indirect immunofluorescence (IIF) assay for detecting anti‐Trypanosoma cruzi IgG in dogs using four chimeric IBMP antigens and latent class analysis. The IIF assay showed suboptimal sensitivity and overall accuracy compared to ELISA and LCA‐based methods.
Ângelo Antônio Oliveira Silva   +13 more
wiley   +1 more source

Agricultural By‐Products as Secondary Risk Matrices: Hazard Occurrence, Contaminant Fate, Mitigation Strategies, and Regulatory Considerations in Food Systems

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT Agricultural by‐products are increasingly valorized as food ingredients within circular food systems. However, their safety cannot be directly inferred from their corresponding primary commodities. Moreover, agricultural by‐products serve as secondary risk matrices by acting as reservoirs or accumulation points for microbiological hazards ...
Vinothini Boopathi   +6 more
wiley   +1 more source

Identification of New Anti‐Trypanosoma brucei Leads: An Integrated CRK12‐Guided Virtual Screen With Experimental Validation

open access: yesChemical Biology &Drug Design, Volume 108, Issue 3, September 2026.
An integrated computational‐experimental workflow enabled CRK12‐guided hit discovery against Trypanosoma brucei under limited structural and ligand data. The workflow of virtual screening and anti‐T. brucei bioassays identified 4 hit compounds, including three low‐micromolar leads (IC50 = 1.47, 0.81, and 1.33 μM). ABSTRACT Human African trypanosomiasis
Qin Li   +11 more
wiley   +1 more source

tArp Is an Actin‐Related Protein Required for Ciliary Function That Is Conserved in Ciliates and Related Eukaryotic Groups

open access: yesJournal of Eukaryotic Microbiology, Volume 73, Issue 5, September/October 2026.
ABSTRACT Cells exhibit a wide range of behaviors due to their diverse molecular systems, which have been established through the molecular evolution of individual species. Protein families generated through gene duplications may be involved in this process. The actin cytoskeleton is no exception.
Miku Kagawa   +8 more
wiley   +1 more source

Galactose starvation in a bloodstream form Trypanosoma brucei UDP-glucose 4'-epimerase conditional null mutant [PDF]

open access: yes, 2006
Galactose metabolism is essential for the survival of Trypanosoma brucei, the etiological agent of African sleeping sickness. T. brucei hexose transporters are unable to transport galactose, which is instead obtained through the epimerization of UDP ...
Turnock, Daniel C.   +2 more
core  

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