Results 61 to 70 of about 51,869 (195)

Chagas disease in Canadian blood donors: 15 years of selective testing

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Chagas disease (Trypanosoma cruzi), prevalent in Mexico, Central and South America, can be transfusion‐transmitted. Selective serological testing of blood donors was implemented over 15 years ago. We describe the trends in infections and characteristics of donors selected for testing.
Sheila F. O'Brien, Mindy Goldman, Antoine Lewin, Samra Uzicanin, Wenli Fan, Steven J. Drews   +5 more
wiley   +1 more source

Prevalence of Haemoparasites among Blood Donors in Calabar, Nigeria

Medical Laboratory Journal, 2021
Background and objectives: Voluntary blood donation is the main source of blood and its components globally. Blood transfusion is essential for management of various diseases but remains as one of the most important causes of disease transmission.
Paul Inyang-Etoh, Etefia Etefia, Chinda Chime, Gabriel Ejezie   +3 more
doaj  

Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman, Janine Aucamp, Helena D. Janse van Rensburg, Christina Kannigadu, Rotondwa Mphephu, Andrew J. Swarts, Keisuke Suganuma, David D. N'Da   +7 more
wiley   +1 more source

Identification of Distinct Interacting Proteins of Giardia lamblia Centrins Using Yeast Two‐Hybrid Assays

Journal of Eukaryotic Microbiology, Volume 73, Issue 4, July/August 2026.
ABSTRACT Giardia lamblia, a protozoan parasite that causes diarrhea in humans, contains two centrins implicated in cellular morphology and cell division. To identify proteins interacting with each G. lamblia centrin (GlCent), we performed a yeast two‐hybrid assay.
Mee Young Shin, Juri Kim, Soon‐Jung Park   +2 more
wiley   +1 more source

The Fantastic Voyage of the Trypanosome: A Protean Micromachine Perfected during 500 Million Years of Engineering

Micromachines, 2018
The human body is constantly attacked by pathogens. Various lines of defence have evolved, among which the immune system is principal. In contrast to most pathogens, the African trypanosomes thrive freely in the blood circulation, where they escape ...
Timothy Krüger, Markus Engstler
doaj   +1 more source

Structural Basis for Nucleobase Activation by the Adenine DNA Glycosylase MutY

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
DNA glycosylase MutY engages its adenine nucleobase substrate in a syn orientation with a catalytic Glu. X‐ray crystal structures of MutY with Glu replaced suggest that a disengaged “on hold” state with anti nucleobase orientation may explain how MutY avoids catastrophic activity at inappropriate adenines.
L. Peyton Russelburg, Merve Demir, Karina Cedeno, Sheila S. David, Martin P. Horvath   +4 more
wiley   +1 more source

Amélioration de la technique de salivation des glossines pour la détection des métatrypanosomes infectants : étude de quelques facteurs biologiques et non biologiques sur le comportement de sondage des glossines

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1995
Le comportement de sondage et de salivation sur lame chauffée est examiné chez trois espèces ou sous-espèces de glossines (Glossina morsitans morsitans, Glossina palpalis gambiensis, Glossina tachinoides) en fonction de certains paramètres (espèce, sexe,
A.M. Gidudu, Dominique Cuisance, Jean-Marc Reifenberg, Jean-Louis Frézil   +3 more
doaj   +1 more source

Networks of Indirect Contact Promote Spread of an Environmentally Transmitted Pathogen in a Highly Social Species

Ecology and Evolution, Volume 16, Issue 6, June 2026.
Using behavioral observations and network simulations, we evaluate direct and indirect transmission of the MTBC pathogen M. mungi in banded mongooses. Incorporating intergroup scent marking reveals that environmentally mediated, socially directed pathways can promote spread at low transmissibility, elevating population prevalence even when direct ...
Jack R. Leitch, Neil R. Jordan, John M. Drake, Michael A. Cant, Kathleen A. Alexander   +4 more
wiley   +1 more source

Extracellular Vesicles of Giardia duodenalis: Unravelling Their Virulence Factors and Potential to Induce Protection Against Experimental Giardiasis

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo, Argüello‐García Raúl, Ortiz‐Lozano Dalia, Salazar‐Villatoro Lizbeth, Pech‐Santiago Edar Onam, Espinosa‐Cantellano Martha, Hernández‐Cueto Daniel, Silva‐Olivares D. Angélica, Betanzos Abigail, Ortega‐Pierres M. Guadalupe   +9 more
wiley   +1 more source

Trypanosoma (Duttonefla) vivax

Parasitology Today, 1987
Although Trypanosoma vivax was first discovered in 1905 (Ref. 1), the fact that most stocks of this parasite are restricted to ruminant hosts has retarded investigation of this species compared with the experimentally more amenable T. brucei and T. congolense. The veterinary importance of T. vivax (Box 1) and a recent report suggesting that T.
Gardiner, Peter R., Wilson, A.J.
openaire   +3 more sources