Results 161 to 170 of about 7,822 (201)

Development of chimeric multivalent proteins for serological diagnosis of African animal trypanosomosis. [PDF]

open access: yesParasitology
Hounyèmè RE   +11 more
europepmc   +1 more source

Alkyl gallates disrupt Trypanosoma brucei lipid droplets. [PDF]

open access: yesPLoS One
Amisigo CM   +3 more
europepmc   +1 more source

Use of fexinidazole in gambiense human African trypanosomiasis: a retrospective analysis of cases treated in Lui Hospital, South Sudan (2018-2024). [PDF]

open access: yesInfection
Mariotti F   +11 more
europepmc   +1 more source

Trypanosoma brucei gambiense Group 2: The Unusual Suspect

open access: yesTrends in Parasitology, 2019
Trypanosoma brucei causes human African trypanosomiasis (HAT). Three subspecies were described: T. b. gambiense (Tbg) and T. b. rhodesiense (Tbr) in humans, and T. b. brucei (Tbb) in animals. Molecular markers subdivided Tbg into two groups: Tbg1 and Tbg2, of which the latter is different from Tbg1 and Tbr (absence of the SRA gene), but ...
Vincent Jamonneau   +2 more
exaly   +6 more sources

Different allele frequencies in Trypanosoma brucei brucei and Trypanosoma brucei gambiense populations

Molecular and Biochemical Parasitology, 1989
Restriction fragment length polymorphism (RFLP) has been analysed in Trypanosoma brucei DNA following hybridization with different DNA probes. This polymorphism seems to be due to allelic variation, and not to variation between sequence duplicates, since the genomic environment of the probed polymorphic fragments is conserved over considerable ...
Paindavoine, Pascale   +4 more
openaire   +2 more sources

Nitric oxide-mediated cytostatic activity on Trypanosoma brucei gambiense and Trypanosoma brucei brucei

Experimental Parasitology, 1992
Macrophages collected from BCG-infected mice or exposed in vitro to interferon-gamma plus lipopolysaccharide developed a cytostatic activity on Trypanosoma brucei gambiense and Trypanosoma brucei brucei. This trypanostatic activity of activated macrophages was inhibited by addition of N-monomethyl-L-arginine, an inhibitor of the L-arginine-nitric oxide
P, Vincendeau   +5 more
openaire   +2 more sources

Differential Effects of Trypanosoma brucei gambiense and Trypanosoma brucei brucei on Rat Macrophages

Journal of Parasitology, 2011
Mammalian immune responses to Trypanosoma brucei infection are important to control of the disease. In rats infected with T. brucei gambiense (Wellcome strain; WS) or T. brucei brucei (interleukin-tat 1.4 strain [ILS]), a marked increase in the number of macrophages in the spleen can be observed.
Kazuhiko, Nishimura   +5 more
openaire   +2 more sources

"Trypanosoma brucei gambiense" : cerebral immunopathology in mice

Acta tropica, 1982
Ninety outbred white adult female mice were infected with Trypanosoma brucei gambiense (GUMS 2, alias LUMP 1237) originating from a Zairian patient and known to produce a low parasitaemia in rodents. The development of cerebral trypanosomiasis was independent upon the number of parasites inoculated per mouse.
A A, Poltera, A, Hochmann, P H, Lambert
openaire   +2 more sources

Purine metabolism in Trypanosoma brucei gambiense

Biochimica Et Biophysica Acta - General Subjects, 1982
Abstract The procyclic forms of Trypanosoma brucei gambiense do not incorporate glycine or serine into ribonucleotides. Although de novo purine synthesis does not occur, all purine bases and ribonucleotides are interconverted, indicating the presence of active salvage pathways. Guanine is actively deaminated to xanthine by guanase activity.
W R, Fish, J J, Marr, R L, Berens
exaly   +3 more sources

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