Results 171 to 180 of about 53,099 (190)
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The Lancet, 1992
The usual first-line treatment for Trypanosoma brucei gambiense sleeping sickness is melarsoprol, but when that fails the outlook has hitherto been grim. The polyamine synthesis inhibitor eflornithine (difluoromethylornithine, DFMO) has emerged as an alternative therapy. 207 patients with late-stage T b gambiense sleeping sickness were treated in rural
F Milord +6 more
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The usual first-line treatment for Trypanosoma brucei gambiense sleeping sickness is melarsoprol, but when that fails the outlook has hitherto been grim. The polyamine synthesis inhibitor eflornithine (difluoromethylornithine, DFMO) has emerged as an alternative therapy. 207 patients with late-stage T b gambiense sleeping sickness were treated in rural
F Milord +6 more
openaire +2 more sources
The challenge of Trypanosoma brucei gambiense sleeping sickness diagnosis outside Africa
The Lancet Infectious Diseases, 2003Sleeping sickness is a lethal African disease caused by parasites of the Trypanosoma brucei subspecies, which is transmitted by tsetse flies. Occasionally, patients are reported outside Africa. Diagnosis of such imported cases can be problematic when the infection is due to Trypanosoma brucei gambiense, the chronic form of sleeping sickness found in ...
Lejon, V. +4 more
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The substitution of procyclic for bloodstream form Trypanosoma brucei gambiense in isoenzyme studies
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1990Examination of 10 enzymes from 8 stocks of Trypanosoma brucei showed that procyclic forms could be substituted for bloodstream forms in isoenzyme studies. T. b. gambiense procyclic forms cultured in vitro offer a better source of material for genetic investigations because this species is usually of low infectivity and virulence to laboratory rodents ...
A, Kaukas +3 more
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[New perspectives in the epidemiology of Trypanosoma brucei gambiense trypanosomiasis].
Bulletin de la Societe de pathologie exotique et de ses filiales, 1986After a quick survey of the latest techniques likely to improve our knowledge of T. brucei gambiense trypanosomiasis, the authors identify the problems set by field epidemiology, the understanding of which is a condition for the development of an appropriate control strategy.
F, Noireau, J P, Gouteux, J L, Frezil
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Mechanism of lysis of Trypanosoma brucei gambiense by human serum.
The Journal of parasitology, 1995Resistance to lysis by human serum (HS) is an important parameter used to distinguish Trypanosoma brucei brucei from both Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Neither the exact nature of the trypanolytic factor (TLF) nor the mechanism of action by which HS lyses susceptible trypanosomes is well understood.
J C, Ortiz-Ordóñez +2 more
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Transactions of the Royal Society of Tropical Medicine and Hygiene, 1970
F, Evens, R, Marsboom, J, Mortelmans
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F, Evens, R, Marsboom, J, Mortelmans
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[Importance of familial contamination in Trypanosoma brucei gambiense trypanosomiasis].
Bulletin de la Societe de pathologie exotique et de ses filiales, 1982Referring to the sociological structure of the family in the Bateke ethnic group which most of the inhabitants of Kwamouth (Bandundu region, Zaïre) are descendants, the author defines the concept to family contamination in trypanosomiasis induced by Trypanosoma brucei gambiense.
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