Results 211 to 220 of about 22,324 (235)
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Mechanism of Lysis of Trypanosoma brucei gambiense by Human Serum
The Journal of Parasitology, 1994Resistance to lysis by human serum (HS) is an important parameter used to distinguish Trypanosoma brucei brucei from both Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Neither the exact nature of the trypanolytic factor (TLF) nor the mechanism of action by which HS lyses susceptible trypanosomes is well understood.
Juan Carlos Ortiz-Ordóñez +3 more
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The role of immunoglobulins in immunity to Trypanosoma brucei gambiense
International Journal for Parasitology, 1977Abstract The effects of IgM and IgG antibody molecules were compared on a weight basis by both agglutination and in vitro protection tests. It was shown that IgM is a better agglutinating antibody and in the presence of complement is also a better neutralizing antibody.
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Transactions of the Royal Society of Tropical Medicine and Hygiene, 1967
Abstract Trypanosoma brucei, T. rhodesiense and T. gambiense were transmitted by Glossina palpalis to 3 chimpanzees; the strain of T. brucei was shown to be non-infective to man. High parasitaemias developed in the chimpanzee infected with T.
D.G. Godfrey, R. Killick-Kendrick
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Abstract Trypanosoma brucei, T. rhodesiense and T. gambiense were transmitted by Glossina palpalis to 3 chimpanzees; the strain of T. brucei was shown to be non-infective to man. High parasitaemias developed in the chimpanzee infected with T.
D.G. Godfrey, R. Killick-Kendrick
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DIFLUOROMETHYLORNITHINE FOR ARSENO-RESISTANT TRYPANOSOMA BRUCEI GAMBIENSE SLEEPING SICKNESS
The Lancet, 198726 patients with arseno-resistant Trypanosoma brucei gambiense trypanosomiasis were treated with difluoromethylornithine (eflornithine), an inhibitor of ornithine decarboxylase, given intravenously, then orally. There was rapid disappearance of trypanosomes in the cerebrospinal fluid (CSF), gradual decrease of CSF lymphocytosis, and parallel ...
C. Guern +4 more
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Long term exposure of Trypanosoma brucei gambiense to pentamidine in vitro
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994In order to study the sensitivity in vitro of Trypanosoma brucei gambiense to pentamidine, 5 x 10(4) parasites were exposed to 0, 0.1, 1.0, 2.0, 10, 100, 1000 and 10,000 micrograms/L of pentamidine isethionate for up to 10 d. The viability of parasites was determined each day by microscopy.
Pierre Cattand +4 more
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Effects of Heparin Administration on Trypanosoma brucei gambiense Infection in Rats
Journal of Parasitology, 2005We examined whether heparin administration influences in vivo trypanosome proliferation in infected rats. Administration of heparin every 8 hr via cardiac catheter inhibited growth of Trypanosoma brucei gambiense and prolonged survival of treated rats.
Yoshihiro Ohnishi +4 more
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Freeze‐Fracture Study of the Bloodstream Form of Trypanosoma brucei gambiense
The Journal of Protozoology, 1990ABSTRACTThe ultrastructure of Trypanosoma brucei gambiense was investigated by the freeze‐fracture method. Three different regions of the continuous plasma membrane; cell body proper, flagellar pocket, and flagellum were compared in density and distribution of the intramembranous particles (IMP's).
Yukio Yoshida +4 more
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Parasite immunology (Print), 2019
Trypanosoma brucei gambiense, an extracellular eukaryotic flagellate parasite, is the main etiological agent of human African trypanosomiasis (HAT) or sleeping sickness.
F. Dauchy +9 more
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Trypanosoma brucei gambiense, an extracellular eukaryotic flagellate parasite, is the main etiological agent of human African trypanosomiasis (HAT) or sleeping sickness.
F. Dauchy +9 more
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Immunological control of chronic "Trypanosoma brucei gambiense" in outbred rodents
Acta tropica, 1984Recent human isolates of Trypanosoma brucei gambiense generally fail to become or remain patent in laboratory rodents. The purpose of this study was to determine if this was due to acquired immunity and if so which immunosuppressive method was the most efficient in raising parasitemia levels.
P, Diffley, J O, Scott
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Zum Feinbau des Periplasten und der Gei�el von Trypanosoma brucei und Trypanosoma gambiense
Zeitschrift f�r Zellforschung und Mikroskopische Anatomie, 1968Elektronenmikroskopische Untersuchungen an Geiselfibrillen und Mikrotubuli des Periplasten von Trypanosomen ergaben, das beide Strukturen aus Protofilamenten aufgebaut sind. Die Protofilamente bestehen aus kettenformig angeordneten globularen Untereinheiten von 45–50 A Durchmesser.
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