Results 11 to 20 of about 9,123 (239)

Proteomic Selection of Immunodiagnostic Antigens for Trypanosoma congolense

PLoS Neglected Tropical Diseases, 2014
Animal African Trypanosomosis (AAT) presents a severe problem for agricultural development in sub-Saharan Africa. It is caused by several trypanosome species and current means of diagnosis are expensive and impractical for field use. Our aim was to discover antigens for the detection of antibodies to Trypanosoma congolense, one of the main causative ...
Jennifer R. Fleming, Lalitha Sastry, Thomas W. M. Crozier, Grant Napier, Lauren A. Sullivan, Michael A. J. Ferguson   +5 more
openalex   +7 more sources

Differential virulence and tsetse fly transmissibility of Trypanosoma congolense and Trypanosoma brucei strains [PDF]

Onderstepoort Journal of Veterinary Research, 2017
African animal trypanosomiasis causes significant economic losses in sub-Saharan African countries because of livestock mortalities and reduced productivity. Trypanosomes, the causative agents, are transmitted by tsetse flies (Glossina spp.).
Purity K. Gitonga, Kariuki Ndung’u, Grace A. Murilla, Paul C. Thande, Florence N. Wamwiri, Joanna E. Auma, Geoffrey N. Ngae, James K. Kibugu, Richard Kurgat, John K. Thuita   +9 more
doaj   +2 more sources

TLR-2 and MyD88-Dependent Activation of MAPK and STAT Proteins Regulates Proinflammatory Cytokine Response and Immunity to Experimental Trypanosoma congolense Infection [PDF]

Frontiers in Immunology, 2019
It is known that Trypanosoma congolense infection in mice is associated with increased production of proinflammatory cytokines by macrophages and monocytes.
Shiby Kuriakose, Chukwunonso Onyilagha, Rani Singh, Folayemi Olayinka-Adefemi, Ping Jia, Jude E. Uzonna   +5 more
doaj   +2 more sources

Characterization of an epimastigote-stage-specific hemoglobin receptor of Trypanosoma congolense [PDF]

, 2016
Background: Since Trypanosorna spp. lack a complete heme synthesis pathway, the parasites are totally dependent on their host for heme throughout all of the stages of their life -cycle.
Shino Yamasaki, Keisuke Suganuma, Junya Yamagishi, Masahito Asada, Naoaki Yokoyama, Shin‐ichiro Kawazu, Noboru Inoue   +6 more
openalex   +5 more sources

Phloroglucinol as a Potential Candidate against Trypanosoma congolense Infection: Insights from In Vivo, In Vitro, Molecular Docking and Molecular Dynamic Simulation Analyses. [PDF]

Molecules, 2022
Abdulrashid NI, Aminu S, Adamu RM, Tajuddeen N, Isah MB, Jatau ID, Aliyu AB, Simelane MBC, Onyike E, Ibrahim MA.   +9 more
europepmc   +3 more sources

In Vivo Efficacy of Curcumin and Curcumin Nanoparticle in Trypanosoma congolense, Broden 1904 (Kinetoplastea: Trypanosomatidae)-Infected Mice. [PDF]

Pathogens, 2023
Molefe-Nyembe NI, Adeyemi OS, Kondoh D, Kato K, Inoue N, Suganuma K.   +5 more
europepmc   +3 more sources

Structural basis for the high specificity of a Trypanosoma congolense immunoassay targeting glycosomal aldolase. [PDF]

PLoS Negl Trop Dis, 2017
Background : Animal African trypanosomosis (AAT) is a neglected tropical disease which imposes a heavy burden on the livestock industry in Sub-Saharan Africa. Its causative agents are Trypanosoma parasites, with T. congolense and T.
Pinto J, Odongo S, Lee F, Gaspariunaite V, Muyldermans S, Magez S, Sterckx YG.   +6 more
europepmc   +4 more sources

Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo. [PDF]

PLoS Pathog, 2021
Awuah-Mensah G, McDonald J, Steketee PC, Autheman D, Whipple S, D'Archivio S, Brandt C, Clare S, Harcourt K, Wright GJ, Morrison LJ, Gadelha C, Wickstead B.   +12 more
europepmc   +3 more sources

Major differences in the dynamics of haematological and biochemical variables between trypanotolerant and susceptible cattle during Trypanosoma congolense infection. [PDF]

BMC Vet Res
Somé GF, Séré M, Chantal I, Somda MB, Dayo GK, Ouaré M, Sakandé H, Sempéré G, Thévenon S, Berthier-Teyssedre D.   +9 more
europepmc   +2 more sources

An African Canine Trypanosomosis Case Import: Is There a Possibility of Creating a Secondary Focus of Trypanosoma congolense Infection in France? [PDF]

Pathogens, 2020
Calvet F, Medkour H, Mediannikov O, Girardet C, Jacob A, Boni M, Davoust B.   +6 more
europepmc   +3 more sources