Results 91 to 100 of about 137,285 (295)
Insect Molecular Biology, EarlyView.Satellite DNAs comprise the major component of the Triatoma rubrofasciata repeatome, highlighting their central role in genome composition and architecture. Satellite DNA families show recent amplification in heterochromatin and older, more divergent satellite DNAs located in euchromatin, indicating distinct evolutionary histories.
Sebastián Pita +8 more
wiley +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 Sulfonamide carbonic anhydrase (CA, EC 4.2.1.1) inhibitors targeting the α-class enzyme from the protozoan pathogen Trypanosoma cruzi, responsible of Chagas disease, were recently reported.
Alane Beatriz Vermelho +4 more
semanticscholar +1 more source
Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model [PDF]
, 2016 Chronic obesity and Chagas disease (caused by the protozoan Trypanosoma cruzi) represent serious public health concerns. The interrelation between parasite infection, adipose tissue, immune system and metabolism in an obesogenic context, has not been ...
Andrada, Marta Cecilia +8 more
core +4 more sources
Immunology, EarlyView.Leprosy, a chronic infectious disease caused by Mycobacterium leprae, manifests in a spectrum of clinical forms and severity. This study investigated the percentage of CD8+ T cells and their subpopulations (CD8bright and CD8dim T cells) in leprosy patients stratified by clinical forms, bacterial load, and age.
Yuri Scheidegger de Castro +7 more
wiley +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2008 As características físico-geográficas da região Ciénega, Jalisco, México a tornam propícia para transmissão do Trypanosoma cruzi, causador da doença de Chagas.
César Gómez-Hernández +5 more
doaj +1 more source
Virtual Screening Based on QSAR and Molecular Docking of Possible Inhibitors Targeting Chagas CYP51
Journal of Chemistry, 2021 Chagas is a neglected tropical disease caused by the parasite Trypanosoma cruzi with no effective treatment in all its forms. There is a need to find more effective therapeutic alternatives with reduced toxicity.
J. Cotuá, H. LLinás, S. Cotes
doaj +1 more source
Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology
Journal of Microscopy, EarlyView.Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz +4 more
wiley +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2011 INTRODUCTION: For a long time, the importance of Chagas disease in Mexico, where many regarded it as an exotic malady, was questioned. Considering the great genetic diversity among isolates of Trypanosoma cruzi, the importance of this biological ...
César Gómez-Hernández +8 more
doaj +1 more source
Likely Autochthonous Transmission of Trypanosoma cruzi to Humans, South Central Texas, USA
Emerging Infectious Diseases, 2017 Chagas disease, caused by Trypanosoma cruzi, is a major neglected tropical disease affecting the Americas. The epidemiology of this disease in the United States is incomplete.
S. Gunter +10 more
semanticscholar +1 more source