Results 41 to 50 of about 47,468 (218)

Characterisation of a cold‐adapted, thermostable glucokinase from psychrophilic Pseudoalteromonas sp. AS‐131 reveals how the enzyme achieves high thermal stability without loss of cold adaptation

open access: yesThe FEBS Journal, EarlyView.
We investigated glucokinase from the psychrophilic Pseudoalteromonas sp. AS‐131 (PsGK), which was isolated from the Antarctic Ocean. Biochemical studies revealed that PsGK is a cold‐adapted enzyme with high thermal stability, in contrast to general cold‐adapted enzymes, which have low thermal stability.
Akane Yato   +10 more
wiley   +1 more source

Virtual Screening Based on QSAR and Molecular Docking of Possible Inhibitors Targeting Chagas CYP51

open access: yesJournal of Chemistry, 2021
Chagas is a neglected tropical disease caused by the parasite Trypanosoma cruzi with no effective treatment in all its forms. There is a need to find more effective therapeutic alternatives with reduced toxicity.
J. Cotuá, H. LLinás, S. Cotes
doaj   +1 more source

Screening for Trypanosoma cruzi infection (Chagas disease) in the Latin American population living with HIV in London

open access: yesHIV Medicine, EarlyView.
Abstract Background There are an estimated 2482 people born in Latin American countries receiving care for HIV in the United Kingdom. Although national guidance recommends screening for Trypanosoma cruzi infection (Chagas disease) in this population, there is no formal screening programme.
Natalie Elkheir   +18 more
wiley   +1 more source

Prevalência de triatomíneos (Hemíptera: Reduviidae: Triatominae) infectados por Trypanosoma cruzi: sazonalidade e distribuição na região Ciénega do Estado de Jalisco, México Prevalence of triatomines (Hemíptera: Reduviidae: Triatominae) infected by Trypanosoma cruzi: seasonality and distribution in the Ciénega region of the State of Jalisco, Mexico

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2008
As características físico-geográficas da região Ciénega, Jalisco, México a tornam propícia para transmissão do Trypanosoma cruzi, causador da doença de Chagas.
César Gómez-Hernández   +5 more
doaj   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

open access: yesJournal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz   +4 more
wiley   +1 more source

Molecular characterization of Trypanosoma cruzi Mexican strains and their behavior in the mouse experimental model

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUCTION: For a long time, the importance of Chagas disease in Mexico, where many regarded it as an exotic malady, was questioned. Considering the great genetic diversity among isolates of Trypanosoma cruzi, the importance of this biological ...
César Gómez-Hernández   +8 more
doaj   +1 more source

Ultrastructural expansion microscopy reveals unexpected levels of glycosome heterogeneity in African trypanosomes

open access: yesJournal of Microscopy, EarlyView.
Abstract Kinetoplastid parasites include several species. Trypanosoma brucei causes African sleeping sickness in humans and a wasting disease nagana in livestock. Trypanosoma cruzi is the causative agent of Chagas disease and Leishmania species cause leishmaniasis, which can present with visceral, cutaneous, or mucocutaneous symptoms.
Heidi Anderson   +2 more
wiley   +1 more source

Plasminogen interaction with Trypanosoma cruzi [PDF]

open access: yesMemórias do Instituto Oswaldo Cruz, 2004
The ability of Trypanosoma cruzi to interact with plasminogen, the zimogenic form of the blood serin protease plasmin, was examined. Immunohistochemistry studies revealed that both forms, epimastigotes and metacyclic trypomastigotes, were able to fix plasminogen in a lysine dependant manner.
Laura Almeida   +4 more
openaire   +4 more sources

Assessment of Leishmania exposure in blood donors from a non‐endemic urban area: A study in São Paulo

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
Ismael Severino de Lima   +14 more
wiley   +1 more source

Novo encontro do Trypanosoma (Megatrypanum) freitasi, parasita do gambá A new finding of Trypanosoma (Megatrypanum) freitasi, parasite of the opossum

open access: yesRevista de Saúde Pública, 1976
Relata-se um novo encontro do Trypanosoma (Megatrypanum) freitasi, raro tripanosomatídeo encontrado no sangue de marsupiais, do gênero Didelphis.
Eduardo Olavo da Rocha e Silva   +2 more
doaj   +1 more source

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