Results 41 to 50 of about 144,739 (262)

Meiotic sex in Chagas disease parasite Trypanosoma cruzi

Nature Communications, 2019
Genetic exchange enables parasites to rapidly transform disease phenotypes and exploit new host populations. Trypanosoma cruzi, the parasitic agent of Chagas disease and a public health concern throughout Latin America, has for decades been presumed to ...
P. Schwabl, H. Imamura, F. Van den Broeck, J. Costales, Jalil Maiguashca-Sánchez, M. Miles, B. Andersson, M. Grijalva, M. Llewellyn   +8 more
semanticscholar   +1 more source

Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]

, 2018
Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo, A Montalvetti, A Rassi, AB Penissi, AE Eakin, AH Kolien, AJ Solari, AM Sánchez, Ana Yecê das Neves Pinto, C Brack, CF Silva Da, D Gonzalez-Pacanowska, DA Campbell, DA Johnston, DJ Hammond, DV Andrade, E Bontempi, E Lozano, E Lozano, E Lozano, EO Ogbadoiyi, ES Garcia, ES Lozano, F Dos Reis, FR Opperdoes, FR Opperdoes, FR Opperdoes, FS Laranja, H Meyer, H Meyer, J Aldunate, J Lukes, J McKerrow, J Mottram, JA Urbina, JA Urbina, JA Urbina, JA Urbina, JC Engel, JC Linder, JCP Dias, JCP Dias, JD Bergstrom, JD Maya, JF Turrens, JJ Marr, JL Avila, JL Avila, Juliano de Toledo, K Lazardi, K Miranda, K Miranda, KH Lee, L Simpson, LV Muschietti, M Meirelles, M Nieto, MC Elias, MCQB Elias, MR Ariyanayagam, MR Ariyanayagam, NM Sayed El, O Campetella, OS Giordano, OS Giordano, P Barrera, P Webster, PF Pimenta, R Docampo, S Sepúlveda-Boza, SD Brengio, SR Wilkinson, T Souto-Padron, T Souto-Padron, T Souto-Padron, T Souto-Padron, TA Shapiro, TS Tiuman, V Jimenez-Ortiz, V Sülsen, VP Sülsen, VP Sülsen, VV Costantino, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, Wanderley de Souza, WE Gutteridge   +90 more
core   +1 more source

Molecular epidemiology of domestic and sylvatic Trypanosoma cruzi infection in rural northwestern Argentina [PDF]

, 2008
Genetic diversity of Trypanosoma cruzi populations and parasite transmission dynamics have been well documented throughout the Americas, but few studies have been conducted in the Gran Chaco ecoregion, one of the most highly endemic areas for Chagas ...
Cardinal, Marta Victoria, Ceballos, Leonardo A., Gurtler, Ricardo Esteban, Kitron, Uriel D., Lanati, Leonardo, Lauricella, Marta A., Levin, Mariano Jorge, Marcet, Paula Lorena, Schijman, Alejandro Gabriel   +8 more
core   +1 more source

ROS and Trypanosoma cruzi: Fuel to infection, poison to the heart

PLoS Pathogens, 2018
The activation of macrophage respiratory burst in response to infection with Trypanosoma cruzi inflicts oxidative damage to the host’s tissues. For decades, the role of reactive oxygen species (ROS) in the elimination of T.
C. Paiva, E. Medei, M. Bozza
semanticscholar   +1 more source

Molecular and antigenic characterization of Trypanosoma cruzi TolT proteins [PDF]

, 2018
Background: TolT was originally described as a Trypanosoma cruzi molecule that accumulated on the trypomastigote flagellum bearing similarity to bacterial TolA colicins receptors.
Agüero, Fernan Gonzalo, Altcheh, Jaime Marcelo, Balouz, Virginia, Buscaglia, Carlos Andres, Camara, María de los Milagros, Campetella, Oscar Eduardo, Canepa, Gaspar Exequiel, Carlevaro, Giannina Alejandra, Carmona, Santiago Javier, Ciocchini, Andres Eduardo, Cortina, María Eugenia, Lobo, Mabel Maite, Melli, Luciano Jorge, Mucci, Juan Sebastián   +13 more
core   +1 more source

Revisiting the Trypanosoma cruzi metacyclogenesis: morphological and ultrastructural analyses during cell differentiation

Parasites & Vectors, 2018
Trypanosoma cruzi uses several strategies to survive in different hosts. A key step in the life-cycle of this parasite is metacyclogenesis, which involves various morphological, biochemical, and genetic changes that induce the differentiation of non ...
C. S. Gonçalves, A. Ávila, W. de Souza, M. C. Motta, D. P. Cavalcanti   +4 more
semanticscholar   +1 more source

Canine Trypanosoma cruzi infection in the Bolivian Chaco [PDF]

, 2018
A cross-sectional study on Trypanosoma cruzi was carried out in 2013 to evaluate the role of dogs as possible source of infection for humans in two rural communities of the highly endemic Bolivian Chaco (Bartolo, Chuquisaca Department, n = 57 dogs; and ...
Bartoloni, Alessandro, Cancrini, Gabriella, Gabrielli, Simona, Gamboa, Herlan, Macchioni, Fabio, Rojas, Patricia, Rojo, David, Roselli, Mimmo, Spinicci, Michele, Totino, Valentina   +9 more
core   +2 more sources

Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure

bioRxiv, 2017
The ability of the Chagas disease agent Trypanosoma cruzi to resist extended in vivo exposure to highly effective trypanocidal compounds prompted us to explore the potential for dormancy and its contribution to failed drug treatments in this infection ...
Fernando Sanchez-Valdez, A. Padilla, Wei Wang, Dylan S Orr, R. Tarleton   +4 more
semanticscholar   +1 more source

Trypanosoma cruzi: circulating antigens

Memorias do Instituto Oswaldo Cruz, 1981
Circulating antigens were detected in sera of mice experimentally infected with a high close of Trypanosoma cruzi by reaction with sera from chronically infected mice.
V. Bongertz, Klaus-Dieter Hungerer, Bernardo Galvão-Castro   +2 more
doaj   +1 more source

Outcomes of Trypanosoma cruzi and Trypanosoma evansi infections on health of Southern coati (Nasua nasua), crab-eating fox (Cerdocyon thous), and ocelot (Leopardus pardalis) in the Brazilian Pantanal

PLoS ONE, 2018
The occurrence of Trypanosoma spp. in wild carnivore populations has been intensively investigated during the last decades. However, the impact of these parasites on the health of free-living infected animals has been largely neglected.
F. M. Santos, G. C. de Macedo, W. Barreto, L. Oliveira‐Santos, C. Garcia, G. Mourão, Grasiela Edith de Oliveira Porfírio, Elizangela Domenis Marino, Marcos Rogério André, L. Perles, Carina Elisei de Oliveira, Gisele Braziliano de Andrade, A. Jansen, Heitor Miraglia Herrera   +13 more
semanticscholar   +1 more source