Bradykinin B2 receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses [PDF]
Although the concept that dendritic cells (DCs) recognize pathogens through the engagement of Toll-like receptors is widely accepted, we recently suggested that immature DCs might sense kinin-releasing strains of Trypanosoma cruzi through the triggering ...
Müller-Esterl Werner +29 more
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Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease. [PDF]
Trypanosoma cruzi, the etiological agent of Chagas disease, is highly genetically diverse. Numerous lines of evidence point to the existence of six stable genetic lineages or DTUs: TcI, TcIIa, TcIIb, TcIIc, TcIId, and TcIIe.
Torrico, Faustino +39 more
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Trypanosoma cruzi, the causative agent of Chagas disease, has at least two principal intraspecific subdivisions, T. cruzi I (TCI) and T. cruzi II (TCII), the latter containing up to five subgroups (a-e).
González, N. +23 more
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INTRODUÇÃO: A pesquisa da fonte alimentar dos triatomíneos auxilia no conhecimento sobre a biologia destes insetos, inclusive para inferir-se a importância dos mesmos como transmissores do Trypanosoma cruzi ao homem.
Marcos Marreiro Villela +3 more
doaj +1 more source
Sex, subdivision, and domestic dispersal of Trypanosoma cruzi lineage I in southern Ecuador. [PDF]
BACKGROUND: Molecular epidemiology at the community level has an important guiding role in zoonotic disease control programmes where genetic markers are suitably variable to unravel the dynamics of local transmission. We evaluated the molecular diversity
Mario J Grijalva +26 more
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The Trypanosoma cruzi metacyclic-specific protein Met-III associates with the nucleolus and contains independent amino and carboxyl terminal targeting elements. [PDF]
Metacyclogenesis in Trypanosoma cruzi involves the differentiation of replicating non-infective epimastigotes into non-replicating metacyclic trypomastigotes.
Gluenz, E +7 more
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Trypanosoma cruzi prevalence and clinical forms in blood donor candidates in Brazil
The prevalence and clinical forms of Trypanosoma cruzi were evaluated among blood donor candidates attended at a general hospital in Rio de Janeiro, Brazil, from January 1997 to April 1999.
Silveira H J +3 more
doaj +3 more sources
Host-Parasite Interactions in Chagas Disease: Genetically Unidentical Isolates of a Single Trypanosoma cruzi Strain Identified In Vitro via LSSP-PCR. [PDF]
The present study aims at establishing whether the diversity in pathogenesis within a genetically diverse host population infected with a single polyclonal strain of Trypanosoma cruzi is due to selection of specific subpopulations within the strain.
Nívia Carolina Nogueira-Paiva +10 more
doaj +1 more source
Synthesis of Naphthoquinones by Pd‐Catalyzed Heck–Matsuda Arylation of Lapachol
Direct Heck–Matsuda arylation of lapachol enables the efficient synthesis of diverse naphthoquinones under homogeneous and heterogeneous palladium catalysis. The methodology features broad substrate scope, gram‐scale applicability, and provides a practical platform for quinone diversification.
Breno U. de Abreu +13 more
wiley +1 more source
Expressão heteróloga de uma trans-sialidase de Trypanosoma cruzi por Trypanosoma rangeli [PDF]
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.O Trypanosoma rangeli é um parasito hemoflagelado, com capacidade de infectar animais incluindo o homem, nas Américas Central e do Sul.
Granucci, Ninna
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