Results 21 to 30 of about 32,421 (180)

Host–Pathogen Interaction Involved in Trypanosoma cruzi Infection

Pathogens, 2022
Chagas disease, or American trypanosomiasis, caused by the protozoan parasite Trypanosoma cruzi (T. cruzi) [...]
Christian Castillo, Ulrike Kemmerling
doaj   +1 more source

Trypanosoma madeirae sp. n.: A species of the clade T. cruzi associated with the neotropical common vampire bat Desmodus rotundus

International Journal for Parasitology: Parasites and Wildlife, 2019
Molecular phylogenetic studies have revealed the growing diversity of bat trypanosomes. Here, 14 isolates from blood samples of the vampire bat Desmodus rotundus (Phyllostomidae) from Rio de Janeiro, Southeast Brazil, were cultivated, and morphologically
Juliana H.S. Barros, Luciana Lima, Armando O. Schubach, Marta M.G. Teixeira   +3 more
doaj   +1 more source

Infectivity of amastigotes of Trypanosoma cruzi [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 1986
The infectivity amastigotes of Trypanosoma cruzi, isolated from the supernatant of the J774G8 macrophage-like cell line infected with trypomastigotes to normal macrophages in vitro was tested. After a period of 1 h of T. cruzi-macrophage interaction about 2% of the mouse peritoneal macrophages had ingested amastigotes.
Carvalho, Tecia Ulisses de, Souza, Wanderley de   +1 more
openaire   +4 more sources

Análise da fonte alimentar de Panstrongylus megistus (Hemiptera, Reduviidae, Triatominae) e sua atual importância como vetor do Trypanosoma cruzi, no Estado de Minas Gerais Analysis on the food source of Panstrongylus megistus (Hemiptera, Reduviidae, Triatominae) and its present importance as a vector for Trypanosoma cruzi, in the State of Minas Gerais

Revista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUÇÃO: A pesquisa da fonte alimentar dos triatomíneos auxilia no conhecimento sobre a biologia destes insetos, inclusive para inferir-se a importância dos mesmos como transmissores do Trypanosoma cruzi ao homem.
Marcos Marreiro Villela, Vera Lúcia Cortiço Corrêa Rodrigues, Cláudio Casanova, João Carlos Pinto Dias   +3 more
doaj   +1 more source

Trypanosoma cruzi prevalence and clinical forms in blood donor candidates in Brazil

Revista de Saúde Pública, 2003
The prevalence and clinical forms of Trypanosoma cruzi were evaluated among blood donor candidates attended at a general hospital in Rio de Janeiro, Brazil, from January 1997 to April 1999.
Silveira H J, Mozart O N, Norberg A N, Pile E A   +3 more
doaj   +3 more sources

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Histopathologic identification of Trypanosoma cruzi (Chagas') encephalitis in an AIDS patient

Human Pathology: Case Reports, 2017
Trypanosoma cruzi (Chagas') encephalitis is an uncommon manifestation of T. cruzi infection, typically seen in immunocompromised patients. Encephalitis results from the reactivation of chronic infection predominately in individuals from endemic areas ...
Dimath Alyemni, Anthony F. Miller, Patricia Couto, Deena Athas, Amity L. Roberts, Miguel Rufail, David W. Andrews, David S. Strayer, Lawrence C. Kenyon   +8 more
doaj   +1 more source

Host-Parasite Interactions in Chagas Disease: Genetically Unidentical Isolates of a Single Trypanosoma cruzi Strain Identified In Vitro via LSSP-PCR. [PDF]

PLoS ONE, 2015
The present study aims at establishing whether the diversity in pathogenesis within a genetically diverse host population infected with a single polyclonal strain of Trypanosoma cruzi is due to selection of specific subpopulations within the strain.
Nívia Carolina Nogueira-Paiva, Paula Melo de Abreu Vieira, Larissa Maris Rezende Oliveri, Kátia da Silva Fonseca, Gwenaelle Pound-Lana, Maykon Tavares de Oliveira, Marta de Lana, Vanja Maria Veloso, Alexandre Barbosa Reis, Washington Luiz Tafuri, Cláudia Martins Carneiro   +10 more
doaj   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

New insights for an old drug: difluoromethylornithine boosts the trypanocidal action of benznidazole on Trypanosoma cruzi in vitro and in vivo

Frontiers in Cellular and Infection Microbiology
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is currently a global health problem. Its multiple forms of transmission, which favor the spread of the infection, and the limited treatment options—still restricted to only two drugs ...
Santiago José Martínez, Santiago José Martínez, María Cristina Vanrell, María Cristina Vanrell, Xiaomo Li, Carolina Carrillo, David M. Engman, Patricia Silvia Romano, Patricia Silvia Romano   +8 more
doaj   +1 more source