Results 51 to 60 of about 47,468 (218)

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Could the Biological Potency of Porcelia macrocarpa R.E. Fries (Annonaceae) be Linked to Its Diverse Metabolite Profile?

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Porcelia macrocarpa is a Brazilian plant species belonging to the Annonaceae family. To date, more than 190 compounds have been identified and/or isolated from this species, with terpenoids comprising the majority (62%). Alkaloids represent the second most abundant class (11%), followed by steroids (4%), acetogenins (4%), fatty acids (4 ...
Fernanda Thevenard   +4 more
wiley   +1 more source

Busca retrospectiva da transmissão maternal da infecção chagásica em pacientes na fase crônica A retrospective search for maternal transmission of Chagas infection from patients in the chronic phase

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2004
Avaliamos a transmissão maternal do Trypanosoma cruzi em 278 filhos de 145 mães com a doença crônica causada por esse protozoário, nascidos após o estabelecimento do diagnóstico materno.
Anis Rassi   +6 more
doaj   +1 more source

Microsomal Hemoproteins in Trypanosoma cruzi

open access: yesExperimental Biology and Medicine, 1971
SummarySpectrophotometry of whole cells, microsomal, mitochondrial, and supernatant fractions of Trypanosoma cruzi (Tulahuen strain, culture forms) shows that the microsomal hemoproteins largely contribute to the heme pigments of the parasite. Both the microsomal and mitochondrial fractions have NADH-ferricyanide reductase, NADH-cytochrome c reductase ...
J F, De Boiso, A O, Stoppani
openaire   +2 more sources

Trypanocidal Effects of Polyprenylated Benzophenone Enriched Brazilian Red Propolis Extract and Its Isolated Constituent

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
In vitro trypanocidal activity of a polyprenylated benzophenone‐enriched Brazilian red propolis extract (SEBz) and its major constituents, guttiferone E/xanthochymol (GUT/XAN) and oblongifolin B (OBL), exhibit in vitro trypanocidal activity against Trypanosoma cruzi, inducing ultrastructural damage with moderate cytotoxicity and no significant ...
Nicoli Dias Oliveira   +9 more
wiley   +1 more source

Molecular characterization of Trypanosoma cruzi Mexican strains and their behavior in the mouse experimental model Caracterização molecular de cepas mexicanas de Trypanosoma cruzi e seu comportamento no modelo experimental do camundongo

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUCTION: For a long time, the importance of Chagas disease in Mexico, where many regarded it as an exotic malady, was questioned. Considering the great genetic diversity among isolates of Trypanosoma cruzi, the importance of this biological ...
César Gómez-Hernández   +8 more
doaj  

Chemical Constituents and Biological Activities of Oxandra (Annonaceae): A Review

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Oxandra (Annonaceae) comprises 29 species distributed across South and Central America. Despite this diversity, the genus remains under‐investigated. This study presents the first comprehensive review of the chemical composition and biological activities of Oxandra species, utilizing databases such as SciFinder, ScienceDirect, PubMed, and ...
Rayssa Cota Lopes   +4 more
wiley   +1 more source

9‐Deoxymuzigadial, a Sesquiterpene Isolated From Drimys brasiliensis (Winteraceae), Displays Reduced Cytotoxicity In Vitro and Modulates Leukocyte Activity and Fibrogenesis In Vivo

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The aims of this study were to investigate in vitro cytotoxic potential and the effects of daily administration during the inflammatory response induced by sponge implants in mice of the sesquiterpene 9‐deoxymuzigadial (9‐DOM), isolated from Drimys brasiliensis (Winteraceae).
Bruno Antonio Ferreira   +7 more
wiley   +1 more source

Strongyloides Antigens Alter Cytokines Responses in Toxoplasma gondii‐Infected BeWo Trophoblast Cells

open access: yesCell Biology International, Volume 50, Issue 1, January 2026.
ABSTRACT The importance of co‐infections is not yet completely understood, and the impact and direction of their effects vary considerably. This study aimed to evaluate the role of total saline extract (TS) and excretory/secretory (ES) products of Strongyloides venezuelensis filarioid larvae on a maternal‐interface cell model during Toxoplasma gondii ...
Fabíola Teixeira Alves   +8 more
wiley   +1 more source

Observaciones sobre trypanosomas en Colombia

open access: yesRevista de la Facultad de Medicina, 1941
I Observaciones sobre trypanosoma cruzi II Observaciones sobre trypanosoma rangeli III Anotaciones sobre un trypanosoma del Dassyprocta ...
Hernando Rey Matiz
doaj  

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