Results 51 to 60 of about 137,285 (295)

Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure

bioRxiv, 2017
The ability of the Chagas disease agent Trypanosoma cruzi to resist extended in vivo exposure to highly effective trypanocidal compounds prompted us to explore the potential for dormancy and its contribution to failed drug treatments in this infection ...
Fernando Sanchez-Valdez, A. Padilla, Wei Wang, Dylan S Orr, R. Tarleton   +4 more
semanticscholar   +1 more source

Structural organization of Trypanosoma cruzi [PDF]

Memórias do Instituto Oswaldo Cruz, 2009
Since the initial description of Trypanosoma cruzi by Carlos Chagas in 1909, several research groups have used different microscopic techniques to obtain detailed information about the various developmental stages found in the life cycle of this intracellular parasite.
openaire   +4 more sources

Molecular epidemiology of domestic and sylvatic Trypanosoma cruzi infection in rural northwestern Argentina [PDF]

, 2008
Genetic diversity of Trypanosoma cruzi populations and parasite transmission dynamics have been well documented throughout the Americas, but few studies have been conducted in the Gran Chaco ecoregion, one of the most highly endemic areas for Chagas ...
Cardinal, Marta Victoria, Ceballos, Leonardo A., Gurtler, Ricardo Esteban, Kitron, Uriel D., Lanati, Leonardo, Lauricella, Marta A., Levin, Mariano Jorge, Marcet, Paula Lorena, Schijman, Alejandro Gabriel   +8 more
core   +1 more source

Outcomes of Trypanosoma cruzi and Trypanosoma evansi infections on health of Southern coati (Nasua nasua), crab-eating fox (Cerdocyon thous), and ocelot (Leopardus pardalis) in the Brazilian Pantanal

PLoS ONE, 2018
The occurrence of Trypanosoma spp. in wild carnivore populations has been intensively investigated during the last decades. However, the impact of these parasites on the health of free-living infected animals has been largely neglected.
F. M. Santos, G. C. de Macedo, W. Barreto, L. Oliveira‐Santos, C. Garcia, G. Mourão, Grasiela Edith de Oliveira Porfírio, Elizangela Domenis Marino, Marcos Rogério André, L. Perles, Carina Elisei de Oliveira, Gisele Braziliano de Andrade, A. Jansen, Heitor Miraglia Herrera   +13 more
semanticscholar   +1 more source

TcI isolates of Trypanosoma cruzi exploit the antioxidant network for enhanced intracellular survival in macrophages and virulence in mice [PDF]

, 2016
Trypanosoma cruzi species is categorized into six discrete typing units (TcI to TcVI) of which TcI is most abundantly noted in the sylvatic transmission cycle and considered the major cause of human disease. In our study, the TcI strains Colombiana (COL),
Basombrío, Miguel Ángel Manuel, Dhiman, Monisha, Garg, Nisha J., Hosakote, Yashoda M., Koo, Sue Jie, Parodi­ Talice, Adriana, Piñeyro, María Dolores, Robello, Carlos, Zago, María Paola   +8 more
core   +2 more sources

On the occurrence of thioredoxin in Trypanosoma cruzi

Acta Tropica, 2006
The full coding sequence for thioredoxin from Trypanosoma cruzi (TcTRX) strain Tulahuen O has been cloned into the pRSETA vector. The protein was expressed in Escherichia coli with an N-terminal extension of six histidine residues for purification through metal ion chromatography.
Piattoni, Claudia Vanesa, Blancato, Victor Sebastian, Miglietta, Hilario Francisco, Iglesias, Alberto Alvaro, Guerrero, Sergio Adrian   +4 more
openaire   +4 more sources

Molecular and antigenic characterization of Trypanosoma cruzi TolT proteins [PDF]

, 2018
Background: TolT was originally described as a Trypanosoma cruzi molecule that accumulated on the trypomastigote flagellum bearing similarity to bacterial TolA colicins receptors.
Agüero, Fernan Gonzalo, Altcheh, Jaime Marcelo, Balouz, Virginia, Buscaglia, Carlos Andres, Camara, María de los Milagros, Campetella, Oscar Eduardo, Canepa, Gaspar Exequiel, Carlevaro, Giannina Alejandra, Carmona, Santiago Javier, Ciocchini, Andres Eduardo, Cortina, María Eugenia, Lobo, Mabel Maite, Melli, Luciano Jorge, Mucci, Juan Sebastián   +13 more
core   +1 more source

The Ly49E receptor inhibits the immune control of acute Trypanosoma cruzi infection [PDF]

, 2016
The protozoan parasite Trypanosoma cruzi circulates in the blood upon infection and invades various cells. Parasites intensively multiply during the acute phase of infection and persist lifelong at low levels in tissues and blood during the chronic phase.
Almeida, Andrade, Antunez, Aune, Avilan, Bern, Cardillo, Carlier, Carnaud, Cesari, Collins, Culbertson, Dowling, Duthie, Duthie, Duthie, Filtjens, Fraser, Frosch, Gritz, Hanke, Keating, Lieke, Lieke, Mekkawy, Meyer Zum Buschenfelde, Mondino, Nagata, Nogueira, Pettengill, Pinazo, Rassi, Robertson, Rottenberg, Santana, Sardinha, Stevenaert, Taveirne, Torrico, Truyens, Truyens, Truyens, Une, Van Beneden, Van Beneden, Van Den Broeck, Van Den Broeck, Vassalli, Wen   +48 more
core   +2 more sources

Análise da fonte alimentar de Panstrongylus megistus (Hemiptera, Reduviidae, Triatominae) e sua atual importância como vetor do Trypanosoma cruzi, no Estado de Minas Gerais Analysis on the food source of Panstrongylus megistus (Hemiptera, Reduviidae, Triatominae) and its present importance as a vector for Trypanosoma cruzi, in the State of Minas Gerais

Revista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUÇÃO: A pesquisa da fonte alimentar dos triatomíneos auxilia no conhecimento sobre a biologia destes insetos, inclusive para inferir-se a importância dos mesmos como transmissores do Trypanosoma cruzi ao homem.
Marcos Marreiro Villela, Vera Lúcia Cortiço Corrêa Rodrigues, Cláudio Casanova, João Carlos Pinto Dias   +3 more
doaj   +1 more source

Evasion of the Immune Response by Trypanosoma cruzi during Acute Infection

Frontiers in Immunology, 2016
Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical disease that affects millions of people mainly in Latin America. To establish a life-long infection, T.
M. Cardoso, J. Reis-Cunha, D. Bartholomeu   +2 more
semanticscholar   +1 more source