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Molecular phylogenetic studies have revealed the growing diversity of bat trypanosomes. Here, 14 isolates from blood samples of the vampire bat Desmodus rotundus (Phyllostomidae) from Rio de Janeiro, Southeast Brazil, were cultivated, and morphologically
Juliana H.S. Barros+3 more
doaj +1 more source
Oral Transmission of Trypanosoma cruzi, Brazilian Amazon
In the Brazilian Amazon, the suspected source of infection in an outbreak of acute Chagas disease involving 10 patients was Euterpe oleracea (açaí berry) juice.
R. Santana+19 more
semanticscholar +1 more source
Infectivity of amastigotes of Trypanosoma cruzi [PDF]
The infectivity amastigotes of Trypanosoma cruzi, isolated from the supernatant of the J774G8 macrophage-like cell line infected with trypomastigotes to normal macrophages in vitro was tested. After a period of 1 h of T. cruzi-macrophage interaction about 2% of the mouse peritoneal macrophages had ingested amastigotes.
Carvalho, Tecia Ulisses de+1 more
openaire +5 more sources
Astrocyte Apoptosis and HIV Replication Are Modulated in Host Cells Coinfected with Trypanosoma cruzi [PDF]
The protozoan Trypanosoma cruzi is the etiological agent of Chagas disease. In immunosuppressed individuals, as it occurs in the coinfection with human immunodeficiency virus (HIV), the central nervous system may be affected. In this regard, reactivation
Burgos, Juan Miguel+5 more
core +1 more source
ROS and Trypanosoma cruzi: Fuel to infection, poison to the heart
The activation of macrophage respiratory burst in response to infection with Trypanosoma cruzi inflicts oxidative damage to the host’s tissues. For decades, the role of reactive oxygen species (ROS) in the elimination of T.
C. Paiva, E. Medei, M. Bozza
semanticscholar +1 more source
Trypanosoma cruzi uses several strategies to survive in different hosts. A key step in the life-cycle of this parasite is metacyclogenesis, which involves various morphological, biochemical, and genetic changes that induce the differentiation of non ...
C. S. Gonçalves+4 more
semanticscholar +1 more source
Structural organization of Trypanosoma cruzi [PDF]
Since the initial description of Trypanosoma cruzi by Carlos Chagas in 1909, several research groups have used different microscopic techniques to obtain detailed information about the various developmental stages found in the life cycle of this intracellular parasite.
openaire +4 more sources
Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]
Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo+90 more
core +1 more source
Canine Trypanosoma cruzi infection in the Bolivian Chaco [PDF]
A cross-sectional study on Trypanosoma cruzi was carried out in 2013 to evaluate the role of dogs as possible source of infection for humans in two rural communities of the highly endemic Bolivian Chaco (Bartolo, Chuquisaca Department, n = 57 dogs; and ...
Bartoloni, Alessandro+9 more
core +2 more sources
Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure
The ability of the Chagas disease agent Trypanosoma cruzi to resist extended in vivo exposure to highly effective trypanocidal compounds prompted us to explore the potential for dormancy and its contribution to failed drug treatments in this infection ...
Fernando Sanchez-Valdez+4 more
semanticscholar +1 more source