Results 1 to 10 of about 316 (141)

Modulation of the Immune Response by Nematode Secreted Acetylcholinesterase Revealed by Heterologous Expression in Trypanosoma musculi. [PDF]

PLoS Pathogens, 2016
Nematode parasites secrete molecules which regulate the mammalian immune system, but their genetic intractability is a major impediment to identifying and characterising the biological effects of these molecules.
Rachel Vaux, Corinna Schnoeller, Rita Berkachy, Luke B Roberts, Jana Hagen, Kleoniki Gounaris, Murray E Selkirk   +6 more
doaj   +4 more sources

Kinetoplast DNA structure, RNA editing patterns and small respiratory Complex I in Trypanosoma musculi [PDF]

Communications Biology
Kinetoplast (k) DNA, a specialized form of mitochondrial DNA in trypanosomes, is composed of catenated maxicircles and minicircles, and is essential for the survival of these parasitic protists.
Ju-Feng Wang, Ying-Xin Bi, Michael Hammond, Julius Lukeš, De-Hua Lai, Zhao-Rong Lun   +5 more
doaj   +3 more sources

Infection with Trypanosoma lewisi or Trypanosoma musculi may promote the spread of Toxoplasma gondii. [PDF]

Parasitology, 2021
Abstract Toxoplasma gondii can infect almost all warm-blooded vertebrates with pathogensis being largely influenced by the host immune status. As important epidemiological hosts, rodents are globally distributed and are also commonly found infected with haemoflagellates, such as those in the ...
Gao JM, Yi SQ, Geng GQ, Xu ZS, Hide G, Lun ZR, Lai DH.   +6 more
europepmc   +6 more sources

Chronic infection with Trypanosoma musculi in congenitally athymic nude mice [PDF]

Infection and Immunity, 1977
Trypanosoma musculi produces a chronic infection with a consistently elevated parasitemia in nude mice. Thymic reconstitution of nude mice restores immunity to the infection.
R G Rank, Dean W Roberts, W P Weidanz
exaly   +6 more sources

Novel insertions in the mitochondrial maxicircle of Trypanosoma musculi, a mouse trypanosome. [PDF]

Parasitology, 2022
AbstractTrypanosoma musculi is a, globally distributed, mouse-specific haemoflagellate, of the family Trypanosomatidae, which shares similar characteristics in morphology with Trypanosoma lewisi. The kinetoplast (mitochondrial) DNA of Trypanosomatidae flagellates is comprised of catenated maxicircles and minicircles. However, genetic information on the
Wang JF, Lin RH, Zhang X, Hide G, Lun ZR, Lai DH.   +5 more
europepmc   +5 more sources

Macrophage function during Trypanosoma musculi infection in mice [PDF]

Infection and Immunity, 1981
Quantitative and functional changes in peritoneal macrophages from mice infected with Trypanosoma musculi were investigated. Increase in the number and size and in the protein content of peritoneal macrophages and the presence of parasites in the peritoneal activity were observed during the course of parasitemia. Induced releases of H2O2 by macrophages
P Vincendeau, R Pautrizel
exaly   +5 more sources

PCR-based identification of Trypanosoma lewisi and Trypanosoma musculi using maxicircle kinetoplast DNA [PDF]

Acta Tropica, 2017
Trypanosoma lewisi, transmitted by rat fleas, is a widespread pathogen specific to rats with records of human infection cases. Its closely related species with global distribution, Trypanosoma musculi, is transmitted between mice by ingestion of infected fleas.
Xiao-Kun, Hong, Xuan, Zhang, Octavio Alejandro, Fusco, You-Gen, Lan, Zhao-Rong, Lun, De-Hua, Lai   +5 more
openaire   +3 more sources

Characterization of antibodies mediating protection and cure of Trypanosoma musculi infection in mice [PDF]

Infection and Immunity, 1985
Plasma samples were collected from mice infected with Trypanosoma musculi at different times postinfection and administered to naive recipient mice either before or during T. musculi infection. The protective and curative activities of these plasma samples were shown to increase as the time of collection postinfection increased; plasma collected at 14 ...
P A Kongshavn
exaly   +5 more sources

Spillover of Trypanosoma lewisi and Trypanosoma musculi Allied Trypanosomes from Rodents to Bats in the Roofs of Human Dwellings: Synanthropic Bats as a Potential New Source of Human Opportunistic Trypanosomes

Zoonotic Diseases
Bats and rodents serve as reservoirs for numerous zoonotic pathogens, including species of Trypanosoma and Leishmania. Domestic rats host the flea-transmitted Trypanosoma (Herpetosoma) lewisi, which can be associated with humans, particularly young or ...
Evaristo Villalba-Alemán, Luciana Lima, Paola Andrea Ortiz, Bruno Rafael Fermino, Gladys Elena Grisante, Carla Monadeli Filgueira Rodrigues, Letícia Pereira Úngari, Néstor Añez, Herakles Antonio Garcia, Marta Maria Geraldes Teixeira   +9 more
doaj   +2 more sources

Trypanosoma musculi infection in the CBA/N mouse

Canadian Journal of Microbiology, 1986
The infection of B-cell deficient CBA/N mice by Trypanosoma musculi resulted in a higher parasitaemia, delayed recovery, and a defective antibody response (IgM and IgG1). CBA/N mice were thus less efficient than CBA/J in controlling the infection. These results indicate that B-cells are involved in the immunological control of this parasite.
P, Vigeant, R, Dubois, P, Viens
openaire   +3 more sources