Macrophage function during Trypanosoma musculi infection in mice [PDF]
Quantitative and functional changes in peritoneal macrophages from mice infected with Trypanosoma musculi were investigated. Increase in the number and size and in the protein content of peritoneal macrophages and the presence of parasites in the peritoneal activity were observed during the course of parasitemia. Induced releases of H2O2 by macrophages
Vincendeau P, Caristan A, Pautrizel R.
exaly +5 more sources
Chronic infection with Trypanosoma musculi in congenitally athymic nude mice [PDF]
Trypanosoma musculi produces a chronic infection with a consistently elevated parasitemia in nude mice. Thymic reconstitution of nude mice restores immunity to the infection.
Rank RG, Roberts DW, Weidanz WP.
exaly +5 more sources
La prevalencia de infecciones por Toxoplasma gondii en el ser humano es de 5-90% según la zona geográfica; en Costa Rica por ejemplo, la seroprevalencia es de un 58%, por lo que es importante comprender algunos procesos inmunológicos, propios en estas ...
Loretta Piccolo-Johanning +3 more
doaj +1 more source
Trypanosoma musculi infection in B-cell-deficient mice. [PDF]
The course of infection with Trypanosoma musculi was assessed in mice deprived of B-lymphocytes by administration, from birth, of rabbit antiserum to mouse immunoglobulin M (IgM). Initial control of parasitemia leading to the first crisis and establishment of the plateau phase was unaffected by lack of B-lymphocyte function, although multiplicative ...
Vargas FD, Viens P, Kongshavn PA.
europepmc +4 more sources
Lipopolysaccharide hyperreactivity of animals infected with Trypanosoma lewisi or Trypanosoma musculi. [PDF]
Rats and mice infected with Trypanosoma lewisi and Trypanosoma musculi, respectively, showed hyperreactivity to lipopolysaccharide (LPS) from gram-negative bacteria. Fatal shock could be precipitated with a dose of LPS 100 to 1,000 times less in infected compared with noninfected animals.
Ferrante A +3 more
europepmc +3 more sources
Natural killer activity in mice infected with Trypanosoma musculi. [PDF]
Trypanosoma musculi infection affected natural killer (NK) activity in mice. In the spleen, an increase of two to three times normal was displayed on days 2 to 4 after inoculation of parasites, followed by rapid decline to a subnormal level of activity that persisted for more than 3 weeks and included the phase of rapid parasite elimination.
Albright JW, Huang KY, Albright JF.
europepmc +4 more sources
Characterization of antibodies mediating protection and cure of Trypanosoma musculi infection in mice [PDF]
Wechsler DS, Kongshavn PA.
exaly +2 more sources
Further characterization of the curative antibodies in Trypanosoma musculi infection. [PDF]
The ability of immune plasma (IP) taken from different donor strains of mice to cure Trypanosoma musculi infection in various recipient mouse strains, when given during the plateau phase of infection, was examined. C57BL/6, B10.A/SgSn, B10.D2/oSn, B10.D2/nSn, DBA/2, and BALB/c strains could be cured of parasitemia (giving 0.4 to 0.8 ml of IP per mouse),
Wechsler DS, Kongshavn PA.
europepmc +3 more sources
Histopathological and immunocytochemical studies of Trypanosoma musculi infection of mice. [PDF]
Mice infected with Trypanosoma musculi developed hyperplasia of the spleen, lymph nodes, and liver; in contrast, their thymuses displayed transient involution. All organs returned to normal in a month or less. There was modest anemia, lasting until the parasites were cleared from the bloodstream, followed by a rapid influx of erythrocytes into the ...
Hirokawa K +3 more
europepmc +4 more sources
Infections with extracellular trypanosomes require control by efficient innate immune mechanisms and can result in the destruction of the mammalian humoral immune system [PDF]
Salivarian trypanosomes are extracellular parasites that affect humans, livestock, and game animals around the world. Through co-evolution with the mammalian immune system, trypanosomes have developed defense mechanisms that allow them to thrive in blood,
Magez, Stefan +3 more
core +1 more source

