Infection with Trypanosoma lewisi or Trypanosoma musculi may promote the spread of Toxoplasma gondii. [PDF]
Abstract Toxoplasma gondii can infect almost all warm-blooded vertebrates with pathogensis being largely influenced by the host immune status. As important epidemiological hosts, rodents are globally distributed and are also commonly found infected with haemoflagellates, such as those in the ...
Gao JM +6 more
europepmc +4 more sources
Novel insertions in the mitochondrial maxicircle of Trypanosoma musculi, a mouse trypanosome. [PDF]
AbstractTrypanosoma musculi is a, globally distributed, mouse-specific haemoflagellate, of the family Trypanosomatidae, which shares similar characteristics in morphology with Trypanosoma lewisi. The kinetoplast (mitochondrial) DNA of Trypanosomatidae flagellates is comprised of catenated maxicircles and minicircles. However, genetic information on the
Wang JF +5 more
europepmc +3 more sources
Lipopolysaccharide hyperreactivity of animals infected with Trypanosoma lewisi or Trypanosoma musculi. [PDF]
Rats and mice infected with Trypanosoma lewisi and Trypanosoma musculi, respectively, showed hyperreactivity to lipopolysaccharide (LPS) from gram-negative bacteria. Fatal shock could be precipitated with a dose of LPS 100 to 1,000 times less in infected compared with noninfected animals.
Ferrante A +3 more
europepmc +3 more sources
Trypanosoma musculi infection in B-cell-deficient mice. [PDF]
The course of infection with Trypanosoma musculi was assessed in mice deprived of B-lymphocytes by administration, from birth, of rabbit antiserum to mouse immunoglobulin M (IgM). Initial control of parasitemia leading to the first crisis and establishment of the plateau phase was unaffected by lack of B-lymphocyte function, although multiplicative ...
Vargas FD, Viens P, Kongshavn PA.
europepmc +4 more sources
Further characterization of the curative antibodies in Trypanosoma musculi infection. [PDF]
The ability of immune plasma (IP) taken from different donor strains of mice to cure Trypanosoma musculi infection in various recipient mouse strains, when given during the plateau phase of infection, was examined. C57BL/6, B10.A/SgSn, B10.D2/oSn, B10.D2/nSn, DBA/2, and BALB/c strains could be cured of parasitemia (giving 0.4 to 0.8 ml of IP per mouse),
Wechsler DS, Kongshavn PA.
europepmc +3 more sources
Histopathological and immunocytochemical studies of Trypanosoma musculi infection of mice. [PDF]
Mice infected with Trypanosoma musculi developed hyperplasia of the spleen, lymph nodes, and liver; in contrast, their thymuses displayed transient involution. All organs returned to normal in a month or less. There was modest anemia, lasting until the parasites were cleared from the bloodstream, followed by a rapid influx of erythrocytes into the ...
Hirokawa K +3 more
europepmc +4 more sources
Natural killer activity in mice infected with Trypanosoma musculi. [PDF]
Trypanosoma musculi infection affected natural killer (NK) activity in mice. In the spleen, an increase of two to three times normal was displayed on days 2 to 4 after inoculation of parasites, followed by rapid decline to a subnormal level of activity that persisted for more than 3 weeks and included the phase of rapid parasite elimination.
Albright JW, Huang KY, Albright JF.
europepmc +4 more sources
Trypanosoma congolense Infections: Induced Nitric Oxide Inhibits Parasite Growth In Vivo
Wild‐type (WT) C57BL/6 mice infected intraperitoneally with 5 × 106 Trypanosoma congolense survive for more than 30 days. C57BL/6 mice deficient in inducible nitric oxide synthase (iNOS−/−) and infected with 103 or 5 × 106 parasites do not control the parasitemia and survive for only 14 ± 7 or 6.8 ± 0.1 days, respectively.
Wenfa Lu +4 more
wiley +1 more source
Bats and rodents serve as reservoirs for numerous zoonotic pathogens, including species of Trypanosoma and Leishmania. Domestic rats host the flea-transmitted Trypanosoma (Herpetosoma) lewisi, which can be associated with humans, particularly young or ...
Evaristo Villalba-Alemán +9 more
doaj +1 more source
Response of inbred mice to infection with a new isolate ofTrypanosoma musculi [PDF]
SummaryA new isolate ofTrypanosoma musculihas been derived from organisms recovered fromMus spretuscaptured in Lisbon, Portugal. The time-course and profiles of infection with this isolate in inbred mice have been compared with those obtained with the existing Partinico II isolate. Infections with the Portuguese isolate are less intense, and controlled
Chiejina, S.N. +3 more
openaire +2 more sources

