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Chagas’ disease is a neglected tropical disease caused by Trypanosoma cruzi which is endemic throughout Latin America and is spread by worldwide migration. Diagnosis is currently limited to serological and molecular techniques having variations regarding their sensitivity and specificity.
Diego Ordóñez +11 more
wiley +1 more source
Characterization of tubulin genes in Trypanosoma rangeli [PDF]
Tubulin genes in Trypanosoma rangeli, the only trypanosome besides T. cruzi to infect humans in America, are organized in homogeneous, alternate alpha and beta gene tandem repeats of 3.8 kb. The basic repeat was cloned, mapped and partially sequenced.
D, Esquenazi +2 more
openaire +2 more sources
The Infection Rates of Trypanosomes in Squirrel Monkeys at Two Sites in the Brazilian Amazon
A study was conducted to determine the prevalence of natural infections by trypanosome species in squirrel monkeys: Saimiri sciureus (Linnaeus) and Saimiri ustus (Geoffroy) caught respectively near 2 hydroelectric plants: Balbina, in the State of ...
Mariangela Ziccardi +1 more
doaj +1 more source
Chagas disease is a neglected tropical disease caused by the parasite Trypanosoma cruzi. Despite the efforts and distinct methodologies, the search of antigens for diagnosis, vaccine, and drug targets for the disease is still needed. The present study is aimed at identifying possible antigens that could be used for diagnosis, vaccine, and drugs targets
Rafael Obata Trevisan +17 more
wiley +1 more source
Metalloproteases in Trypanosoma rangeli-infected Rhodnius prolixus [PDF]
Protease activities in the haemolymph and fat body in a bloodsucking insect, Rhodnius prolixus, infected with Trypanosoma rangeli, were investigated. After SDS-polyacrylamide gel electrophoresis containing gelatin as substrate, analysis of zymograms performed on samples of different tissues of controls and insects inoculated or orally infected with ...
Feder, D +3 more
openaire +4 more sources
Karyotype variability in Trypanosoma rangeli
SUMMARYThe molecular karyotypes of several different protozoan parasites show high intra-species variation, including different kinetoplastids such as Trypanosoma brucei, Trypanosoma cruzi and Leishmania ssp. In this study, the molecular karyotype of Trypanosoma rangeli was examined.
Henriksson, J. +4 more
openaire +2 more sources
In this study the effect of eight DNA topoisomerase inhibitors on the growth Trypanosoma rangeli epimastigotes in cell culture was investigated. Among the eight compounds tested, idarubicin was the only compound that displayed promising trypanocidal ...
Momodou Jobe +14 more
doaj +1 more source
Trypanosoma rangeli (Tejera, 1920): observations upon pleomorphism [PDF]
Meta-trypomastigotes of Trypanosoma rangeli Tejera, 1920, harvested from LIT medium, were inoculated i.p. or s.c. into 6, 16, and 26 g NMRI mice, these representing increasing degrees of immunological maturity. In all cases, similar pleomorphic patterns were observed.
Urdaneta-Morales, S., Tejero, F.
openaire +4 more sources
Trypanosoma rangeli sialidase lacks trans-sialidase activity [PDF]
Extracts and tissue culture supernatants of axenic forms of T. rangeli were assayed for the presence of sialidase and trans-sialidase activities. Using sialyl(alpha 2-3)lactose, sialyl(alpha 2-6)lactose, poly(alpha 2-8)N-acetylneuraminic acid, fetuin and 4-methylumbelliferyl-N-acetylneuraminic acid as sialic acid donors, and lactose as a sialic acid ...
L C, Pontes-de-Carvalho +2 more
openaire +2 more sources
The morphological sequence of Trypanosoma rangeli development in the alimentary canal of Rhodnius prolixus, is described, with observation made in dissected guts from 6 hours to 45 days post-infection.
N. Añez
doaj +1 more source

