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Annals of Tropical Medicine & Parasitology, 1991
Professor Kershaw's encouragement of the development of anion-exchange separation of African trypanosomes from blood led to two decades of activity when, for the first time, considerable progress was made in the intrinsic characterization of these parasites. Such characterization depended on establishing high infections in laboratory rodents.
P, Dukes, J J, McNamara, D G, Godfrey
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Professor Kershaw's encouragement of the development of anion-exchange separation of African trypanosomes from blood led to two decades of activity when, for the first time, considerable progress was made in the intrinsic characterization of these parasites. Such characterization depended on establishing high infections in laboratory rodents.
P, Dukes, J J, McNamara, D G, Godfrey
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The Trypanosome Flagellar Pocket
Nature Reviews Microbiology, 2009Trypanosomes are important disease agents and excellent models for the study of evolutionary cell biology. The trypanosome flagellar pocket is a small invagination of the plasma membrane where the flagellum exits the cytoplasm and participates in many cellular processes.
Mark C Field, Mark Carrington
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The Cytoskeleton of trypanosomes
Parasitology Today, 1990From the concept of cells as mere bags full of enzymes, cell biology has come a long way towards understanding the highly complex structural organization of eukaryotic cells. The cytoskeleton, ie. the complex of fibrous elements that are crucial for cell shape, motility and the structural organization of cytoplasm and cell membranes, is now recognized ...
T, Seeback, A, Hemphill, D, Lawson
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International Journal for Parasitology, 1994
The nuclear chromatin of trypanosomes is organised in the form of nucleosome filaments. When soluble chromatin is prepared under suitable conditions, a regular array of nucleosomes can be shown by electron microscopy. Chromatin of blood stream as well as procyclic culture forms of Trypanosoma brucei brucei and of T.
Hecker H +4 more
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The nuclear chromatin of trypanosomes is organised in the form of nucleosome filaments. When soluble chromatin is prepared under suitable conditions, a regular array of nucleosomes can be shown by electron microscopy. Chromatin of blood stream as well as procyclic culture forms of Trypanosoma brucei brucei and of T.
Hecker H +4 more
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1973
Publisher Summary This chapter discusses trypanosomes of tailless Amphibia (Anura). The chapter deals with taxonomic and phylogenetic considerations, morphology, electron microscopy and cytology, life cycles, distribution, the vertebrate host and pathogenesis, physiological processes, the invertebrate host, media, physiology, and biochemistry applied
J E, Bardsley, R, Harmsen
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Publisher Summary This chapter discusses trypanosomes of tailless Amphibia (Anura). The chapter deals with taxonomic and phylogenetic considerations, morphology, electron microscopy and cytology, life cycles, distribution, the vertebrate host and pathogenesis, physiological processes, the invertebrate host, media, physiology, and biochemistry applied
J E, Bardsley, R, Harmsen
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Mitochondrial ribosomes in a trypanosome
Biochemical and Biophysical Research Communications, 2003The nature, and even the existence, of trypanosome mitochondrial ribosomes has been the subject of some debate. We investigated this further in the insect trypanosome, Crithidia fasciculata. In sucrose gradients of parasite lysates, mitochondrial ribosomal RNA co-sediments at approximately 35S with nascent peptides synthesized in the presence of the ...
Ivor, Tittawella +2 more
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Antigenic Variation in Trypanosomes
The American Journal of Tropical Medicine and Hygiene, 1977Abstract The several species of African trypanosomes pathogenic to man and domestic livestock may evade the immune response through a process of antigenic variation. This phenomenon is the major obstacle to immunization. Variation may be recognized in the form of sequential changes in the serological characteristics of the trypanosome
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