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The Cytoskeleton of trypanosomes
Parasitology Today, 1990From the concept of cells as mere bags full of enzymes, cell biology has come a long way towards understanding the highly complex structural organization of eukaryotic cells. The cytoskeleton, ie. the complex of fibrous elements that are crucial for cell shape, motility and the structural organization of cytoplasm and cell membranes, is now recognized ...
T, Seeback, A, Hemphill, D, Lawson
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International Journal for Parasitology, 1994
The nuclear chromatin of trypanosomes is organised in the form of nucleosome filaments. When soluble chromatin is prepared under suitable conditions, a regular array of nucleosomes can be shown by electron microscopy. Chromatin of blood stream as well as procyclic culture forms of Trypanosoma brucei brucei and of T.
Hecker H +4 more
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The nuclear chromatin of trypanosomes is organised in the form of nucleosome filaments. When soluble chromatin is prepared under suitable conditions, a regular array of nucleosomes can be shown by electron microscopy. Chromatin of blood stream as well as procyclic culture forms of Trypanosoma brucei brucei and of T.
Hecker H +4 more
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1973
Publisher Summary This chapter discusses trypanosomes of tailless Amphibia (Anura). The chapter deals with taxonomic and phylogenetic considerations, morphology, electron microscopy and cytology, life cycles, distribution, the vertebrate host and pathogenesis, physiological processes, the invertebrate host, media, physiology, and biochemistry applied
J E, Bardsley, R, Harmsen
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Publisher Summary This chapter discusses trypanosomes of tailless Amphibia (Anura). The chapter deals with taxonomic and phylogenetic considerations, morphology, electron microscopy and cytology, life cycles, distribution, the vertebrate host and pathogenesis, physiological processes, the invertebrate host, media, physiology, and biochemistry applied
J E, Bardsley, R, Harmsen
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Antigenic Variation in Trypanosomes
The American Journal of Tropical Medicine and Hygiene, 1977Abstract The several species of African trypanosomes pathogenic to man and domestic livestock may evade the immune response through a process of antigenic variation. This phenomenon is the major obstacle to immunization. Variation may be recognized in the form of sequential changes in the serological characteristics of the trypanosome
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Mitochondrial ribosomes in a trypanosome
Biochemical and Biophysical Research Communications, 2003The nature, and even the existence, of trypanosome mitochondrial ribosomes has been the subject of some debate. We investigated this further in the insect trypanosome, Crithidia fasciculata. In sucrose gradients of parasite lysates, mitochondrial ribosomal RNA co-sediments at approximately 35S with nascent peptides synthesized in the presence of the ...
Ivor, Tittawella +2 more
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The trypanosome flagellar pocket
Nature Reviews Microbiology, 2009Trypanosomes are important disease agents and excellent models for the study of evolutionary cell biology. The trypanosome flagellar pocket is a small invagination of the plasma membrane where the flagellum exits the cytoplasm and participates in many cellular processes.
Mark C, Field, Mark, Carrington
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The Molecular Evolution of Trypanosomes
Parasitology Today, 1999The absence of a fossil record has meant that the evolution of protozoa has remained largely a matter for speculation. Recent advances in molecular biology and phylogenetic analysis, however, are allowing the 'history written in the genes' to be interpreted. Here, Jamie Stevens and Wendy Gibson review progress in reconstruction of trypanosome phylogeny
Stevens, JR, Gibson, WC
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Infecting Triatomines with Trypanosomes
2020The infection of triatomines with trypanosomes can be performed with different forms of the parasite, and the procedure is important not only for vector-parasite interaction studies but also for maintaining the infectivity of parasite strains, which guarantees more realistic biological and molecular investigations.
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The African trypanosome genome
International Journal for Parasitology, 2000The haploid nuclear genome of the African trypanosome, Trypanosoma brucei, is about 35 Mb and varies in size among different trypanosome isolates by as much as 25%. The nuclear DNA of this diploid organism is distributed among three size classes of chromosomes: the megabase chromosomes of which there are at least 11 pairs ranging from 1 Mb to more than
N M, El-Sayed +4 more
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1999
Abstract As mentioned, the trypanosomes are closely related to the leishmaniae, and their zoologic classification follows the same lines (see Chapter 4; Corliss, 1994). Trypanosomes are known in general as the blood flagellates, and under natural conditions they occur in humans and many other species of animals.
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Abstract As mentioned, the trypanosomes are closely related to the leishmaniae, and their zoologic classification follows the same lines (see Chapter 4; Corliss, 1994). Trypanosomes are known in general as the blood flagellates, and under natural conditions they occur in humans and many other species of animals.
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