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IL-10 Plays a Critical Role in Mitigating Acute Anaemia Development During African Trypanosome Infection. [PDF]

open access: yesPathogens
Živalj M   +9 more
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Elusive trypanosomes

Annals of Tropical Medicine & Parasitology, 1991
Professor Kershaw's encouragement of the development of anion-exchange separation of African trypanosomes from blood led to two decades of activity when, for the first time, considerable progress was made in the intrinsic characterization of these parasites. Such characterization depended on establishing high infections in laboratory rodents.
P, Dukes, J J, McNamara, D G, Godfrey
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The Cytoskeleton of trypanosomes

Parasitology Today, 1990
From the concept of cells as mere bags full of enzymes, cell biology has come a long way towards understanding the highly complex structural organization of eukaryotic cells. The cytoskeleton, ie. the complex of fibrous elements that are crucial for cell shape, motility and the structural organization of cytoplasm and cell membranes, is now recognized ...
T, Seeback, A, Hemphill, D, Lawson
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Trypanosome glucose transporters

Molecular and Biochemical Parasitology, 1998
, by contrast adopts an intracellularenvironment within their mammalian hosts. Inva-sion and passage through different anatomicallocations within insect vectors also distinguishesthe parasites.All trypanosome species use glucose as a crucialsource of energy, and all have specific plasmamembrane transporters to facilitate the uptake ofthis molecule. Four
Michael P Barrett   +2 more
exaly   +3 more sources

The chromatin of trypanosomes

International Journal for Parasitology, 1994
The nuclear chromatin of trypanosomes is organised in the form of nucleosome filaments. When soluble chromatin is prepared under suitable conditions, a regular array of nucleosomes can be shown by electron microscopy. Chromatin of blood stream as well as procyclic culture forms of Trypanosoma brucei brucei and of T.
Hecker H   +4 more
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The Trypanosomes of Anura

1973
Publisher Summary This chapter discusses trypanosomes of tailless Amphibia (Anura). The chapter deals with taxonomic and phylogenetic considerations, morphology, electron microscopy and cytology, life cycles, distribution, the vertebrate host and pathogenesis, physiological processes, the invertebrate host, media, physiology, and biochemistry applied
J E, Bardsley, R, Harmsen
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Antigenic Variation in Trypanosomes

The American Journal of Tropical Medicine and Hygiene, 1977
Abstract The several species of African trypanosomes pathogenic to man and domestic livestock may evade the immune response through a process of antigenic variation. This phenomenon is the major obstacle to immunization. Variation may be recognized in the form of sequential changes in the serological characteristics of the trypanosome
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Mitochondrial ribosomes in a trypanosome

Biochemical and Biophysical Research Communications, 2003
The nature, and even the existence, of trypanosome mitochondrial ribosomes has been the subject of some debate. We investigated this further in the insect trypanosome, Crithidia fasciculata. In sucrose gradients of parasite lysates, mitochondrial ribosomal RNA co-sediments at approximately 35S with nascent peptides synthesized in the presence of the ...
Ivor, Tittawella   +2 more
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