Results 251 to 260 of about 54,903 (309)
Genome organization and DNA accessibility control antigenic variation in trypanosomes
Nature, 2018 Many evolutionarily distant pathogenic organisms have evolved similar survival strategies to evade the immune responses of their hosts. These include antigenic variation, through which an infecting organism prevents clearance by periodically altering the
Laura S M Müller +2 more
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Nature Communications, 2020 Persistent pathogens have evolved to avoid elimination by the mammalian immune system including mechanisms to evade complement. Infections with African trypanosomes can persist for years and cause human and animal disease throughout sub-Saharan Africa ...
Olivia J S Macleod +2 more
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Coordination of the Cell Cycle in Trypanosomes
Annual Review of Microbiology, 2019 Trypanosomes have complex life cycles within which there are both proliferative and differentiation cell divisions. The coordination of the cell cycle to achieve these different divisions is critical for the parasite to infect both host and vector.
Richard John Wheeler +2 more
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Annals of Tropical Medicine & Parasitology, 1991
Professor Kershaw's encouragement of the development of anion-exchange separation of African trypanosomes from blood led to two decades of activity when, for the first time, considerable progress was made in the intrinsic characterization of these parasites. Such characterization depended on establishing high infections in laboratory rodents.
P, Dukes, J J, McNamara, D G, Godfrey
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Professor Kershaw's encouragement of the development of anion-exchange separation of African trypanosomes from blood led to two decades of activity when, for the first time, considerable progress was made in the intrinsic characterization of these parasites. Such characterization depended on establishing high infections in laboratory rodents.
P, Dukes, J J, McNamara, D G, Godfrey
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Molecular detection of Megatrypanum trypanosomes in tabanid flies
Medical and Veterinary Entomology, 2020Trypanosomes of the subgenus Megatrypanum have been isolated from many mammalian hosts around the world. They are usually non‐pathogenic, although they may confuse the parasitological diagnosis of trypanosomosis.
J. Werszko +5 more
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African trypanosomes and brain infection – the unsolved question
Biological Reviews, 2017Stefan Mogk, Michael Duszenko
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Trypanosome glucose transporters
Molecular and Biochemical Parasitology, 1998, by contrast adopts an intracellularenvironment within their mammalian hosts. Inva-sion and passage through different anatomicallocations within insect vectors also distinguishesthe parasites.All trypanosome species use glucose as a crucialsource of energy, and all have specific plasmamembrane transporters to facilitate the uptake ofthis molecule. Four
M P, Barrett +4 more
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The molecular arms race between African trypanosomes and humans
Nature Reviews Microbiology, 2014Etienne Pays, Benoit Vanhollebeke
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Trypanosome Signaling—Quorum Sensing
Annual Review of Microbiology, 2021African trypanosomes are responsible for important diseases of humans and animals in sub-Saharan Africa. The best-studied species is Trypanosoma brucei, which is characterized by development in the mammalian host between morphologically slender and stumpy forms. The latter are adapted for transmission by the parasite's vector, the tsetse fly.
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Trends in Parasitology, 2008
Genetic exchange in Trypanosoma brucei is now well characterized. It is a key tool that has enabled an understanding of important parasite genetic traits and underpinned the Trypanosoma brucei genome project. However, a key aspect that has eluded us is the point in the trypanosome life cycle where genetic exchange occurs.
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Genetic exchange in Trypanosoma brucei is now well characterized. It is a key tool that has enabled an understanding of important parasite genetic traits and underpinned the Trypanosoma brucei genome project. However, a key aspect that has eluded us is the point in the trypanosome life cycle where genetic exchange occurs.
openaire +2 more sources