Results 1 to 10 of about 755,682 (398)
Identification of trypsin-degrading commensals in the large intestine
Nature, 2022 Increased levels of proteases, such as trypsin, in the distal intestine have been implicated in intestinal pathological conditions 1 – 3 . However, the players and mechanisms that underlie protease regulation in the intestinal lumen have remained unclear.
Eiichiro Watanabe +2 more
exaly +2 more sources
Nature Communications, 2018 Hydrogen bonds are key interactions determining protein-ligand binding affinity and therefore fundamental to any biological process. Unfortunately, explicit structural information about hydrogen positions and thus H-bonds in protein-ligand complexes is ...
Roberto Gaspari +2 more
exaly +2 more sources
Epithelial expression and function of trypsin-3 in irritable bowel syndrome
Gut, 2017 Objectives Proteases are key mediators of pain and altered enteric neuronal signalling, although the types and sources of these important intestinal mediators are unknown.
Alexandre Denadai-Souza +2 more
exaly +2 more sources
Ultrasensitive surface-enhanced Raman scattering detection of trypsin based on anti-aggregation of 4-mercaptopyridine-functionalized silver nanoparticles: an optical sensing platform toward proteases [PDF]
Nanoscale, 2013 In this work, a simple and sensitive surface-enhanced Raman scattering (SERS) strategy was developed for recognition and detection of trypsin, by using anti-aggregation of 4-mercaptopyridine (4-MPY)-functionalized silver nanoparticles (AgNPs) based on ...
Chen, Lingxin +3 more
core +2 more sources
Frontiers in Physiology, 2021 Trypsin is a serine protease that is synthesized by the gut epithelial cells of female mosquitoes; it is the enzyme that digests the blood meal. To study its molecular regulation, Culex quinquefasciatus late trypsin was purified by diethylaminoethyl ...
Dov Borovsky +4 more
doaj +1 more source
Biosensors, 2021 The determination of protease activity is very important for disease diagnosis, drug development, and quality and safety assurance for dairy products. Therefore, the development of low-cost and sensitive methods for assessing protease activity is crucial.
Ivan Piovarci +4 more
doaj +1 more source
Circulation, 1954 Studies were carried out regarding the effect of intravenous trypsin on rabbits. These included investigations into the toxicity and the tendency for the production of intravascular coagulation. The effect on artificial preformed thrombi was also observed.
A, TAYLOR, I S, WRIGHT
openaire +2 more sources
Safety evaluation of food enzyme trypsin from porcine pancreas
EFSA Journal, 2021 The food enzyme trypsin (EC 3.4.21.4) is extracted from porcine pancreas by Novozymes A/S. The food enzyme is intended to be used for hydrolysis of whey proteins employed as ingredients in infant formulae, follow‐on formulae and in food for special ...
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) +27 more
doaj +1 more source
Foods, 2023 Texture is an important sensory attribute for overall quality and consumer acceptance of prawns. However, texture is affected during cold storage due to the proteolytic activity of endogenous proteases, resulting in poor quality and a short shelf life ...
Amalina Ibrahim +5 more
doaj +1 more source