Results 1 to 10 of about 513,729 (298)
Proteomics beyond trypsin [PDF]
FEBS Journal, 2015 Peptide‐centered shotgun analysis of proteins has been the core technology in mass spectrometry based proteomics and has enabled numerous biological discoveries, such as the large‐scale charting of protein–protein interaction networks, the quantitative analysis of protein post‐translational modifications and even the first drafts of the human proteome.
Styliani Tsiatsiani, Albert J R Heck
exaly +6 more sources
Identification of trypsin-degrading commensals in the large intestine
Nature, 2022 Increased levels of proteases, such as trypsin, in the distal intestine have been implicated in intestinal pathological conditions 1 – 3 . However, the players and mechanisms that underlie protease regulation in the intestinal lumen have remained unclear.
Eiichiro Watanabe +2 more
exaly +2 more sources
Nature Communications, 2018 Hydrogen bonds are key interactions determining protein-ligand binding affinity and therefore fundamental to any biological process. Unfortunately, explicit structural information about hydrogen positions and thus H-bonds in protein-ligand complexes is ...
Roberto Gaspari +2 more
exaly +2 more sources
Epithelial expression and function of trypsin-3 in irritable bowel syndrome
Gut, 2017 Objectives Proteases are key mediators of pain and altered enteric neuronal signalling, although the types and sources of these important intestinal mediators are unknown.
Alexandre Denadai-Souza +2 more
exaly +2 more sources
A Model of Demasking and Hydrolysis of Peptide Bonds During Tryptic Digestion of β-Casein and β-Lactoglobulin [PDF]
MoleculesThe prediction of polypeptide chain fragmentation during digestion (proteolysis) of protein substrates by trypsin was carried out for globular β-lactoglobulin (β-LG) and micellar β-casein (β-CN).
Mikhail M. Vorob’ev
doaj +2 more sources
Inactivation Methods of Trypsin Inhibitor in Legumes: A Review
Journal of Food Science, 2018 Sara Avilés-Gaxiola +2 more
exaly +2 more sources
Frontiers in Physiology, 2021 Trypsin is a serine protease that is synthesized by the gut epithelial cells of female mosquitoes; it is the enzyme that digests the blood meal. To study its molecular regulation, Culex quinquefasciatus late trypsin was purified by diethylaminoethyl ...
Dov Borovsky +4 more
doaj +1 more source
Shipin gongye ke-ji, 2022 Objective: To investigate the changes of endogenous enzyme activity and muscle quality characteristics of Sword prawn (Parapenaeopsis hardwickii) under cold storage. Methods: Sword prawn (Parapenaeopsis hardwickii) was taken as the research object.
Ting ZHOU +5 more
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Effect of Adropin on Pancreas Exocrine Function in a Rat Model: A Preliminary Study
Animals, 2022 The aim was to investigate the potential effect of adropin (ADR) on pancreatic–biliary juice (PBJ) secretion (volume, protein content, trypsin activity) in a rat model.
Małgorzata Kapica +5 more
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Microorganisms, 2023 Biofilms consist of microbial communities enclosed in a self-produced extracellular matrix which is mainly responsible of biofilm virulence. Targeting this matrix could be an effective strategy to control biofilms.
Samah Mechmechani +6 more
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