Results 261 to 270 of about 509,022 (312)

LDI, A Lipid Droplet Inhibitor, Disrupts Lipid Accumulation and Modulates Hepatic Lipid Profiles in Fatty Liver

Advanced Materials, EarlyView.
The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim, Yeojin Kim, Sanjita Paudel, In Young Kang, Suyeon Kim, Jeesoo Kim, Sunmi Park, Seung‐Hoi Koo, Hyun Sung Kim, Dae Won Jun, Jinyoung Park, Hyunbeom Lee, Joonseok Lee   +12 more
wiley   +1 more source

Geniposide, a potential therapeutical candidate for acute pancreatitis, inhibited trypsinogen-activated CBS degradation and remodeled transsulfuration metabolic flux. [PDF]

Redox Biol
Gao J, Long Y, Li J, Wang Y, Wang R, Yang J, Zhang J, Han C, Xia Q, Du D.   +9 more
europepmc   +1 more source

PiP‐Plex: A Particle‐in‐Particle System for Multiplexed Quantification of Proteins Secreted by Single Cells

Advanced Materials, EarlyView.
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier, Byeong‐Ui Moon, Mojra Janta‐Polczynski, Yonatan Morocz, Fabian Svahn, Molly Shen, Ljuboje Lukic, Lidija Malic, Teodor Veres, Andy Ng, David Juncker   +10 more
wiley   +1 more source

Single-Virus Lipid-Mixing Study of Sendai Virus Provides Insight into Fusion Mechanism. [PDF]

ACS Omega
Ji L, Yuan D, Park A, Bai K, Rawle RJ.
europepmc   +1 more source

Interaction between insulin receptor and a peptide derived from a trypsin inhibitor purified from tamarind seed: An in silico screening of insulin-like peptides

Ana Francisca Teixeira Gomes, Wendjilla Fortunato de Medeiros, Lucas Lima Bezerra, Anna Beatriz Santana Luz, Francisco Canindé de Sousa Júnior, Sancha Helena de Lima Vale, Elizeu Antunes dos Santos, Norberto de Kássio Vieira Monteiro, Ana Heloneida de Araújo Morais   +8 more
openalex   +1 more source

A Soft Microrobot for Single‐Cell Transport, Spheroid Assembly, and Dual‐Mode Drug Screening

Advanced Materials, EarlyView.
A soft, untethered hydrogel microrobot enables precise single‐cell delivery, self‐assembly into 3D spheroids, and real‐time thermal actuation. Driven by light‐induced convection and embedded with gold nanorods and temperature sensors, the microrobot guides cells, modulates local microenvironments, and supports drug testing.
Philipp Harder, Nergishan İyisan, Yukun Wang, Berna Özkale   +3 more
wiley   +1 more source

LEKTI-Grafted Sunflower Trypsin Inhibitor: A Potential Therapeutic for Skin Diseases. [PDF]

J Med Chem
Mah J, Jayarajan V, Huang X, Di WL, Macmillan D.   +4 more
europepmc   +1 more source

Inactivation of human interleukin-2 (IL-2) by alpha 2-macroglobulin-trypsin complexes.

, 1986
Wolfgang Borth, M. Teodorescu
openalex   +1 more source

Additive Manufacturing of Molecular Architecture Encoded Stretchable Polyethylene Glycol Hydrogels and Elastomers

Advanced Materials, EarlyView.
Bottlebrush molecular architecture prevents the crystallization of high molecular weight polyethylene glycol (PEG) based polymers, enabling highly stretchable photocurable PEG hydrogels and elastomers for high‐performance conductive solvent‐free electrolytes at room temperature and for additive manufacturing of complex architectures and multi‐material ...
Baiqiang Huang, Myoeum Kim, Pu Zhang, Emmanuel Oduro, Daniel A. Rau, Li‐Heng Cai   +5 more
wiley   +1 more source

Application of tergitol in liver decellularization and bioink preparation based on the obtained extracellular matrix. [PDF]

Front Bioeng Biotechnol
Mirosław P, Kosowska K, Serafin W, Piwowar R, Romanik-Chruścielewska A, Westphal K, Wszoła M, Klak M.   +7 more
europepmc   +1 more source