Results 241 to 250 of about 674,005 (346)

Detection of gas bubbles and local voids in molecular simulations using burbuja. [PDF]

Protein Sci
Muñiz-Chicharro A, Votapka LW, Amaro RE.   +2 more
europepmc   +1 more source

Isolierung eines Trypsininhibitors und zweier Trypsin-Plasmin-Inhibitoren aus den Samenblasen von Meerschweinchen

, 1970
Edwin Fink
openalex   +1 more source

Trypsin Partially Cleaves Apolipoprotein A-I (ApoA-I) Precursor into Mature ApoA-I Hindering the Quantification of Naturally Occurring ApoA-I Proteoforms by Liquid Chromatography in Multiple Reaction Monitoring Mode Mass Spectrometry (LC-MRM-MS)

Carmen Llorens-Cebrià, Norberto Núñez-Seral, Yolanda Villena-Ortiz, Irene Martínez-Díaz, María José Soler, Roser Ferrer, Conxita Jacobs-Cachá, Joan López-Hellín   +7 more
openalex   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Peptides Derived From Reactive Center Loops Inhibit Digestive Trypsin-Like Enzymes in Lepidopteran Pests. [PDF]

Arch Insect Biochem Physiol
Paulo DGS, Schneider JR, Meriño-Cabrera Y, Wurlitzer WB, de Andrade RJ, Santos ILB, Rodrigues MCNG, de Almeida Barros R, da Silva Júnior NR, Lima MG, Vilela CC, Ferla NJ, de Oliveira HJR, de Almeida Oliveira MG.   +13 more
europepmc   +1 more source

Trypsin Encapsulated Nanoparticle to Improve Growth Performance in Labeo Rohita (Hamilton) Fingerling Fed with a Zero-Fishmeal Diet

Da u. ruhi Pde, Pallath Muhammed Nuzaiba, Subodh Gupta, Tincy Varghese   +3 more
openalex   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Dietary Trypsin Inhibitors Lower Serum Triacylglycerol Level in Rats

, 2008
Misao Tashiro, Sayuri Sawada, Saki Takeda   +2 more
openalex   +2 more sources

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Pathologically relevant trypsinogen activation in pancreatitis. [PDF]

Am J Physiol Gastrointest Liver Physiol
Geisz-Fremy A.
europepmc   +1 more source