Results 291 to 300 of about 712,349 (416)

Zonated Copper‐Driven Breast Cancer Progression Countered by a Copper‐Depleting Nanoagent for Immune and Metabolic Reprogramming

Advanced Science, EarlyView.
Spatially resolved multiomics reveals that high‐copper zones are closely associated with tumor metastasis, immune‐desert phenotypes, and oxidative‐phosphorylation (OXPHOS)‐dependent proliferation. A targeted bacterial nanovesicle delivering copper‐depleting agents effectively reduces tumor copper levels, inhibits OXPHOS‐dependent tumor growth, and ...
Lin Chen, Saibo Ma, Hao Wu, Lingna Zheng, Yunpeng Yi, Guangnian Liu, Baoyi Li, Jiayi Sun, Yang Du, Bing Wang, Yike Liu, Cheng Zhang, Jing Chang, Yuheng Pang, Wenjing Wang, Meng Wang, Motao Zhu   +16 more
wiley   +1 more source

Analysis of Protein Inhibitors of Trypsin in Quinoa, Amaranth and Lupine Seeds. Selection and Deep Structure-Function Characterization of the Amaranthus caudatus Species. [PDF]

Int J Mol Sci
Hernández de la Torre M, Covaleda-Cortés G, Montesinos L, Covaleda D, Ortiz JC, Piñol J, Bautista JM, Castillo JP, Reverter D, Avilés FX.   +9 more
europepmc   +1 more source

Favorable effect of trypsin in a case of laryn‐geal epithelioma; exhibition of case [PDF]

, 1907
Homer Dupuy
openalex   +1 more source

Tumoroid Model Reveals Synergistic Impairment of Metabolism by Iron Chelators and Temozolomide in Chemo‐Resistant Patient‐derived Glioblastoma Cells

Advanced Science, EarlyView.
This study investigates the metabolic vulnerabilities of glioblastoma (GBM), an aggressive brain tumor. Research demonstrates that iron chelation therapy, in combination with standard chemotherapy, significantly enhances the efficacy of treatment against resistant GBM cells in a 3D tumoroid model.
Meitham Amereh, Amir Seyfoori, Shahla Shojaei, Sarah Lane, Tian Zhao, Mahdieh Shokrollahi Barough, Julian J. Lum, Patrick Walter, Mohsen Akbari   +8 more
wiley   +1 more source

Rotavirus Spreads in a Spatially Controlled Manner. [PDF]

Cells
Passarelli GV, Doldan P, Metz-Zumaran C, Keser Y, Boulant S, Stanifer ML.   +5 more
europepmc   +1 more source

THE INHIBITION OF β- AND γ-CHYMOTRYPSIN AND TRYPSIN BY DIISOPROPYL FLUOROPHOSPHATE

, 1952
Eugene F. Jansen, A.K. Balls
openalex   +1 more source

The Effect of Trypsin on Hemagglutination by Murine Encephalomyelitis Virus (GDVII) [PDF]

, 1952
Marion C. Morris
openalex   +1 more source

A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis

Advanced Science, EarlyView.
The dynamic interplay between central respiratory chemoreceptors and the respiratory central pattern generator is essential for maintaining stable respiratory rhythm and patterns, particularly during sleep. This study offers novel insights into the anatomical, molecular, and functional characteristics of a medullary network involving the nucleus ...
Tianjiao Deng, Xinyi Jing, Liuqi Shao, Yakun Wang, Congrui Fu, Hongxiao Yu, Xiaoyi Wang, Xue Zhao, Fanrao Kong, Yake Ji, Xiaochen Tian, Wei He, Shangyu Bi, Luo Shi, Hanqiao Wang, Fang Yuan, Sheng Wang   +16 more
wiley   +1 more source

Multiplexed phosphoproteomics of low cell numbers using SPARCE. [PDF]

Commun Biol
Gaizley EJ, Chen X, Bhamra A, Enver T, Surinova S.   +4 more
europepmc   +1 more source

Machine Learning‐Enhanced Optimization for High‐Throughput Precision in Cellular Droplet Bioprinting

Advanced Science, EarlyView.
A high‐throughput droplet‐based cellular bioprinting platform enhanced with machine learning optimizes five key printing parameters—bioink viscosity, nozzle size, printing time, printing pressure, and cell concentration—to enable accurate prediction of droplet size.
Jaemyung Shin, Ryan Kang, Kinam Hyun, Zhangkang Li, Hitendra Kumar, Kangsoo Kim, Simon S. Park, Keekyoung Kim   +7 more
wiley   +1 more source