Results 101 to 110 of about 3,225,670 (405)

Protease inhibitors of Cajanus conferring resistance to pod borer of pigeonpea (Cajanus cajan L. Millsp.)

open access: yesElectronic Journal of Plant Breeding, 2017
Pigeonpea is susceptible to pod borer damage with resistance lacking in its primary gene pool. Many Cajanus species harbor high levels of resistance. Host plant resistance can play an important role in minimizing the extent of losses due to insects and ...
Sandhya Srikanth   +4 more
doaj   +1 more source

EFFECT OF INFRA-RED AND ULTRAVIOLET RADIATION ON STERILIZATION AND TRYPSIN INHIBITOR DEACTIVATION OF COWPEA SEEDS [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2021
Experiments were carried out through summer season 2019 in the Rice Mechanization centre at Meet El-Deeba, Kafr El-Sheikh Governorate to study the effect of infra-red radiation and ultraviolet radiation on protein, trypsin inhibitor and total microbial ...
Tarek FOUDA   +3 more
doaj  

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash   +6 more
wiley   +1 more source

The Diversity of Four Anti-nutritional Factors in Common Bean

open access: yesHorticultural Plant Journal, 2016
Anti-nutritional factors such as lectins, saponin, trypsin inhibitor and phytic acid are endogenous substances in the common bean (Phaseolus vulgaris L.).
Rui Shang   +7 more
doaj   +1 more source

A neutrophil-dependent pathway for the generation of a neutral peptide mediator: partial characterization of components and control by alpha-1-antitrypsin. [PDF]

open access: yes, 1974
A biologically active neutral peptide mediator is cleaved from a plasma protein substrate by an alpha-1-antitrypsin-inhibitable serine protease apparently residing on the membrane of the human neutrophil. The peptide mediator has an approximate mol wt of
Austen, KF, Goetzl, EJ, Wintroub, BU
core  

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

open access: yesFEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda   +9 more
wiley   +1 more source

An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behavior [PDF]

open access: yes, 2016
Serpins are important regulators of proteolytic pathways with an antiprotease activity that involves a conformational transition from a metastable to a hyperstable state. Certain mutations permit the transition to occur in the absence of a protease; when
Faull, Sarah V.   +14 more
core   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Proteinaceous receptors for the import of mitochondrial precursor proteins [PDF]

open access: yes, 1984
Mild trypsin treatment of isolated Neurospora mitochondria strongly inhibits their ability to bind and import the precursors of several mitochondrial proteins.
Neupert, Walter   +2 more
core  

Structural Basis for Accelerated Cleavage of Bovine Pancreatic Trypsin Inhibitor (BPTI) by Human Mesotrypsin*

open access: yesJournal of Biological Chemistry, 2008
Human mesotrypsin is an isoform of trypsin that displays unusual resistance to polypeptide trypsin inhibitors and has been observed to cleave several such inhibitors as substrates.
Moh’d A. Salameh   +3 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy