Results 221 to 230 of about 3,279,235 (401)

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Urinary trypsin inhibitor: anti-inflammatory effects in septic mice and molecular insights in bacterial lipoprotein-induced THP-1 cells. [PDF]

Cent Eur J Immunol
Zhu D, Yin B, Wu D, Huang M, Zhou S.
europepmc   +1 more source

A Prospective Cohort Study of Inter-Alpha-Trypsin Inhibitor Heavy Chain 4 as a Serologic Marker in Relation to Severity and Functional Outcome of Acute Intracerebral Hemorrhage. [PDF]

Neuropsychiatr Dis Treat, 2023
Shentu HS, Chen YH, Cheng ZY, Fu B, Fu YH, Zheng SF, Li C.   +6 more
europepmc   +1 more source

Studies on the physiological role of urinary trypsin inhibitors

, 1988
Tadahiro Shikimi, Michio Suda, Syusaku SUZUKI   +2 more
openalex   +1 more source

Transgenic expression of pancreatic secretory trypsin inhibitor-1 rescues SPINK3-deficient mice and restores a normal pancreatic phenotype.

American Journal of Physiology - Gastrointestinal and Liver Physiology, 2010
J. Romac, M. Ohmuraya, Cathy M. Bittner, M. Faraz Majeed, Steven R Vigna, J. Que, Brian E. Fee, T. Wartmann, K. Yamamura, R. Liddle   +9 more
semanticscholar   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Recombinant human urinary trypsin inhibitor improves the immunological function of splenic dendritic cells in mice with acute lung injury. [PDF]

Eur J Med Res
Wang T, Liu W, Li J, Wan Y, Su H, Qi A.
europepmc   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source

Inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4) in saliva of pigs: evaluation of two commercially available ELISA kits for its measurement and distribution of its main components. [PDF]

PLoS One
Ortín-Bustillo A, Martínez-Subiela S, Cerón JJ, González-Bulnes A, Tvarijonaviciute A, Muñoz-Prieto A.   +5 more
europepmc   +1 more source

Inactivation of Soybean Trypsin Inhibitor by Dielectric-Barrier Discharge Plasma and Its Safety Evaluation and Application. [PDF]

Foods, 2022
Xu Y, Sun Y, Huang K, Li J, Zhong C, He X.   +5 more
europepmc   +1 more source