Advancements in Inactivation of Soybean Trypsin Inhibitors [PDF]
FoodsSoybean Trypsin Inhibitors (STIs) in soy-based foods have negative effects on soybean protein digestion and pancreatic health of humans. The inactivation of STIs is a critical unit operation aimed at enhancing the nutritional properties of soy-based ...
Zhanjun Luo +7 more
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The occurrence of a trypsin inhibitor in brain [PDF]
Biochemical Journal, 1967 1. The tryptic hydrolysis of benzoyl-dl-argininyl-beta-naphthylamide is inhibited by homogenates of human and ox brain. 2. The inhibitor is associated primarily with the membranous portion of the particulate matter, and is not found in the 90000g supernatant fraction. 3. The reaction of the inhibitor with trypsin is rapid. 4.
A. S. Brecher, N. M. Quinn
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The Reactive Site of Trypsin Inhibitors
Journal of Biological Chemistry, 1966 Virgin soybean trypsin inhibitor has 1 NH2-terminal aspartic acid or asparagine residue and no COOH-terminal residues that can be released by carboxypeptidase B. Upon incubation with 1 mole % of trypsin for 24 hours at pH 3.75, virgin inhibitor is converted to a modified inhibitor which has 2 NH2 terminals aspartic acid or asparagine and isoleucine ...
Kyoichi Ozawa, M. Laskowski
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Trypsin inhibitors: promising candidate satietogenic proteins as complementary treatment for obesity and metabolic disorders? [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 The increase in non-communicable chronic diseases has aroused interest in the research of adjuvants to the classic forms of treatments. Obesity and metabolic syndrome are the main targets of confrontation because they relate directly to other chronic ...
Vanessa Cristina Oliveira de Lima +3 more
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Comparison of Conventional and Microwave Treatment on Soymilk for Inactivation of Trypsin Inhibitors and In Vitro Protein Digestibility [PDF]
Foods, 2018 Soymilk is lower in calories compared to cow’s milk, since it is derived from a plant source (no cholesterol) and is an excellent source of protein. Despite the beneficial factors, soymilk is considered as one of the most controversial foods in the world.
Brinda Harish Vagadia +4 more
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Pancreatic trypsin inhibitor. 2. Reaction with trypsin [PDF]
Biochemical Journal, 1953 N. M. Green, Elizabeth Work
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In vivo imaging with fluorescent smart probes to assess treatment strategies for acute pancreatitis. [PDF]
PLoS ONE, 2013 BACKGROUND AND AIMS: Endoprotease activation is a key step in acute pancreatitis and early inhibition of these enzymes may protect from organ damage.
Abhiruchi Agarwal +8 more
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Developments in plant breeding for improved nutritional quality of soya beans II. Anti-nutritional factors [PDF]
, 2000 Nutritional value of most plant materials is limited by the presence of numerous naturally occurring compounds which interfere with nutrient digestion and absorption.
Clarke, E, Wiseman, J
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Engineering trypsin for inhibitor resistance [PDF]
Protein Science, 2015 AbstractThe development of effective protease therapeutics requires that the proteases be more resistant to naturally occurring inhibitors while maintaining catalytic activity. A key step in developing inhibitor resistance is the identification of key residues in protease‐inhibitor interaction. Given that majority of the protease therapeutics currently
Teaster Baird +4 more
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Measurement of the Proteinase Inhibitors of the Bovine Pancreas by Radioimmunoassay [PDF]
, 1976 Bovine pancreas contains two polypeptide trypsin inhibitors that are not homologous and differ in their inhibitory activity towards chymotrypsin, kallikrein, elastase, and other serine proteinases. The Kunitz inhibitor and the Kazal inhibitor are present
Fink, Edwin +2 more
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