Results 221 to 230 of about 256,479 (340)

Vertical Membrane‐Free Organ‐on‐a‐Chip for High‐Throughput In Vitro Studies and Drug Screening

open access: yesAdvanced Materials Technologies, EarlyView.
This novel microfluidic organ‐on‐a‐chip (OoC) platform enables cost‐effective, high‐throughput in vitro modeling. With vertical compartmentalization and gravity‐driven flow, it eliminates porous membranes and external pumps. Successfully generating intestine, cartilage, and tendon models, this study demonstrates drug responses, including 5‐fluorouracil
Xavier Barceló   +5 more
wiley   +1 more source

Arabidopsis Kunitz Trypsin Inhibitors in Defense Against Spider Mites. [PDF]

open access: yesFront Plant Sci, 2018
Arnaiz A   +5 more
europepmc   +1 more source

Growth Factor‐Loaded Mesoporous Silica Particles, Incorporated in Electrospun PCL Fibres, Provide Topographical and Chemical Cues for Tendon Tissue Engineering

open access: yesAdvanced Materials Technologies, EarlyView.
Electrospinning enables the hierarchical assembly of nanofiber‐based scaffolds for tissue engineering. However, encapsulated proteins often undergo structural changes. This study used mesoporous silica nanoparticles (MSNs) as protective carriers, mitigating protein denaturation and supporting controlled release.
Vera Citro   +5 more
wiley   +1 more source

Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease. [PDF]

open access: yesSci Rep, 2019
Ashfaq-Khan M   +9 more
europepmc   +1 more source

Protein Proteinase Inhibitors in Male Sex Glands and their Secretions [PDF]

open access: yes, 1973
Fink, Edwin   +6 more
core  

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

Nitration of Wheat Amylase Trypsin Inhibitors Increases Their Innate and Adaptive Immunostimulatory Potential in vitro. [PDF]

open access: yesFront Immunol, 2018
Ziegler K   +10 more
europepmc   +1 more source

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