Results 21 to 30 of about 261,497 (358)

Measurement of the Proteinase Inhibitors of the Bovine Pancreas by Radioimmunoassay [PDF]

, 1976
Bovine pancreas contains two polypeptide trypsin inhibitors that are not homologous and differ in their inhibitory activity towards chymotrypsin, kallikrein, elastase, and other serine proteinases. The Kunitz inhibitor and the Kazal inhibitor are present
Fink, Edwin, Greene, Lewis J., Peeters, H.   +2 more
core   +1 more source

Inhibitory Effect of Protease Inhibitors on Larval Midgut Protease Activities and the Performance of Plutella xylostella (Lepidoptera: Plutellidae)

Frontiers in Physiology, 2019
Plutella xylostella L. (diamondback moth) is a pest of cruciferous plants. To understand the relationship among protease inhibitors, protease activities and the growth and development of this insect, the activities of midgut proteases of P.
Aiping Zhao, Aiping Zhao, Yin Li, Yin Li, Chunmeng Leng, Chunmeng Leng, Ping Wang, Yiping Li, Yiping Li   +8 more
doaj   +1 more source

Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1. [PDF]

PLoS ONE, 2013
Cystine-knot miniproteins define a class of bioactive molecules with several thousand natural members. Their eponymous motif comprises a rigid structured core formed by six disulfide-connected cysteine residues, which accounts for its exceptional ...
Bernhard Glotzbach, Michael Reinwarth, Niklas Weber, Sebastian Fabritz, Michael Tomaszowski, Heiko Fittler, Andreas Christmann, Olga Avrutina, Harald Kolmar   +8 more
doaj   +1 more source

Mitigation of antinutritional factors and protease inhibitors of defatted winged bean-seed proteins using thermal and hydrothermal treatments: Denaturation/unfolding coupled hydrolysis mechanism

Current Research in Food Science, 2022
The inactivation of antinutritional factors, protease inhibitors within winged bean protein was induced by two respective method treatments. The physical method based on steam vapor that was conducted using an autoclave and chemical method consisting on ...
Sami Saadi, Nazamid Saari, Hasanah Mohd Ghazali, Mohammed Sabo Abdulkarim   +3 more
doaj   +1 more source

CRYSTALLINE SOYBEAN TRYPSIN INHIBITOR [PDF]

Journal of General Physiology, 1946
A study has been made of the general properties of crystalline soybean trypsin inhibitor. The soy inhibitor is a stable protein of the globulin type of a molecular weight of about 24,000. Its isoelectric point is at pH 4.5. It inhibits the proteolytic action approximately of an equal weight of crystalline trypsin by combining with trypsin to form a ...
openaire   +7 more sources

Development of a novel, high-affinity ssDNA trypsin inhibitor

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Inhibitors of serine proteases are not only extremely useful in the basic research but are also applied extensively in clinical settings. Using Systematic Evolution of Ligands by Exponential Enrichment (SELEX) approach we developed a family of novel ...
Stanislaw Malicki, Miroslaw Ksiazek, Pawel Majewski, Aleksandra Pecak, Piotr Mydel, Przemyslaw Grudnik, Grzegorz Dubin   +6 more
doaj   +1 more source

Primary structure of potato Kunitz-type serine proteinase inhibitor [PDF]

, 2000
The serine proteinase inhibitor (PSPI-51) isolated from potato tubers (Solanum tuberosum L,) comprises two protein species with pi 5.2 and 6.3, denoted as PSPI-21-5.2 and PSPI-21-6.3, respectively.
Mentele, Reinhard, Mosolov, Vladimir V., Revina, Tatyana A., Valueva, Tatyana A.   +3 more
core   +1 more source

Crystal structures of a plant trypsin inhibitor from Enterolobium contortisiliquum (EcTI) and of its complex with bovine trypsin. [PDF]

PLoS ONE, 2013
A serine protease inhibitor from Enterolobium contortisiliquum (EcTI) belongs to the Kunitz family of plant inhibitors, common in plant seeds. It was shown that EcTI inhibits the invasion of gastric cancer cells through alterations in integrin-dependent ...
Dongwen Zhou, Yara A Lobo, Isabel F C Batista, Rafael Marques-Porto, Alla Gustchina, Maria L V Oliva, Alexander Wlodawer   +6 more
doaj   +1 more source

Determinação da atividade antitríptica em proteínas de produtos do amendoim isoladas por cromatografia de afinidade

Química Nova, 2014
The peanut is an oleaginous plant of high nutritional value, a source of protein and a trypsin inhibitor. Trypsin inhibitors are proteins present in the vegetable kingdom, considered anti-nutritional factors for animals.
Jéssica Morais de Araújo, Jussara Cristina Alves, Thayane Kerbele Oliveira das Neves Peixoto, Amanda Fernandes de Medeiros, Richele Janaína de Araújo Machado, Alexandre Coelho Serquiz, Renata Alexandra Moreira das Neves, Elizeu Antunes dos Santos, Adriana Ferreira Uchôa, Ana Heloneida de Araújo Morais   +9 more
doaj   +1 more source

Overexpression of soybean trypsin inhibitor genes decreases defoliation by corn earworm (Helicoverpa zea) in soybean (Glycine max) and Arabidopsis thaliana

Frontiers in Plant Science, 2023
Trypsin inhibitors (TIs) are widely distributed in plants and are known to play a protective role against herbivores. TIs reduce the biological activity of trypsin, an enzyme involved in the breakdown of many different proteins, by inhibiting the ...
Mst Shamira Sultana, Mst Shamira Sultana, Mitra Mazarei, Mitra Mazarei, Juan Luis Jurat-Fuentes, Tarek Hewezi, Reginald J. Millwood, C. Neal Stewart, C. Neal Stewart   +8 more
doaj   +1 more source