Results 141 to 150 of about 14,721 (198)
Identification of Natural Compounds Triggering MRGPRX2-Mediated Calcium Flux and Degranulation in RBL-2H3 Cells. [PDF]
Zhang L +8 more
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Avapritinib reduces symptoms and mast cell burden in systemic mastocytosis. [PDF]
Nöldeke P +4 more
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Unexpected anaphylaxis to tranexamic acid confirmed by drug provocation testing in orthopedic surgery: A case report. [PDF]
Song SE, Lee AR.
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Expression of α-tryptase and β-tryptase by human basophils
Journal of Allergy and Clinical Immunology, 2004Background α and β-Tryptase levels in serum are clinical tools for the evaluation of systemic anaphylaxis and systemic mastocytosis. Basophils and mast cells are known to produce these proteins. Objective The current study examines the effect of the α,β-tryptase genotype on basophil tryptase levels and the type of tryptase stored in these cells ...
Lawrence B Schwartz
exaly +2 more sources
Archives of Biochemistry and Biophysics, 1991
Rat mast cell tryptase is located largely if not totally in the cell's secretory granules. When the active site reagent [3H]diisopropyl fluorophosphate was used to label tryptase and chymase simultaneously, the ratio of tryptase:chymase active sites was determined to be 0.05. In comparison to chymase and tryptase in other species and chymase in the rat,
D, Lagunoff, A, Rickard, C, Marquardt
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Rat mast cell tryptase is located largely if not totally in the cell's secretory granules. When the active site reagent [3H]diisopropyl fluorophosphate was used to label tryptase and chymase simultaneously, the ratio of tryptase:chymase active sites was determined to be 0.05. In comparison to chymase and tryptase in other species and chymase in the rat,
D, Lagunoff, A, Rickard, C, Marquardt
openaire +2 more sources
BOVINE TRYPTASE: PURIFICATION AND CHARACTERIZATION
Biological Chemistry Hoppe-Seyler, 1992Bovine tryptase, a mast cell trypsin-like protease, was isolated from liver capsula and from mast cells obtained from the same tissue. The purification procedure which leads to an increase in tryptase activity of 850 fold, involves high salt extraction, hydrophobic interaction chromatography on octyl-Sepharose and affinity chromatography on heparin ...
Fiorucci, L, Erba, F, Ascoli, F
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Human skin tryptase: purification, partial characterization and comparison with human lung tryptase
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1988Human skin tryptase was isolated using stepwise low- and high-salt extraction and further purified 448-fold with 33% yield using octyl-Sepharose CL-4B hydrophobic affinity chromatography, Sephacryl S-200 gel filtration and finally octyl-Sepharose CL-4B or cellulose phosphate ion exchange chromatography.
I T, Harvima +3 more
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Biomarkers of anaphylaxis, beyond tryptase
Current Opinion in Allergy & Clinical Immunology, 2015The purpose of this study is to describe the current knowledge regarding mediators involved in anaphylactic reactions, with a special focus on key effector cells and mechanisms.New insight into the potential relevance of pathways other than mast cell degranulation has been unravelled, such as the role of cytokines, platelet activation factor, lipid ...
Anna, Sala-Cunill, Victoria, Cardona
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Expression of alpha-tryptase and beta-tryptase by human basophils.
The Journal of allergy and clinical immunology, 2004Alpha and beta-tryptase levels in serum are clinical tools for the evaluation of systemic anaphylaxis and systemic mastocytosis. Basophils and mast cells are known to produce these proteins.The current study examines the effect of the alpha,beta-tryptase genotype on basophil tryptase levels and the type of tryptase stored in these cells.Tryptase ...
Sherryline, Jogie-Brahim +4 more
openaire +2 more sources

