Results 141 to 150 of about 1,375,182 (353)

Lactobacillus Salivarius‐Derived Indole‐3‐Acetic Acid Promotes AHR‐PARP1 Axis‐Mediated DNA Repair to Mitigate Intestinal Aging

Advanced Science, EarlyView.
Indole‐3‐acetic acid (IAA) acting as one of the aryl hydrocarbon receptor (AHR) endogenous ligands is identified to be derived from Lactobacillus salivarius via its catalytic enzyme (ALDH) rather than host cells. Lactobacillus salivarius and IAA supplementation effectively mitigate intestinal aging by facilitating AHR‐poly (ADP‐ribose) polymerase 1 ...
Zheng Cao, Cui Zhang, Hehua Lei, Weichuan Lin, Wenkai Yu, Xin Gao, Yanmeng He, Xinzhi Li, Qingwei Xiang, Zhiwen Zhang, Weifei Luo, Andrew D. Patterson, Limin Zhang, Gang Chen   +13 more
wiley   +1 more source

Microglial Rack1 Deficiency Alleviates Alzheimer's Disease Pathology through Enhancing IGF1‐Mediated Astrocytic Phagocytosis

Advanced Science, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder. This study demonstrates that microglial Rack1 deficiency decreased Aβ deposition and neuroinflammation and ameliorated cognitive impairments in AD model mice by enhancing IGF1‐mediated astrocytic phagocytosis.
Jingdan Zhang, Yanling He, Pin Yang, Hengchang Zhang, Yueyang Tong, Lingling Jiang, Zehan Li, Meichen Yan, Xiaoheng Li, Qinghu Yang, Jing Yang, Zengqiang Yuan, Jiyan Zhang, Jinbo Cheng   +13 more
wiley   +1 more source

Influence of Xiaoyaosan on depressive-like behaviors in chronic stress-depressed rats through regulating tryptophan metabolism in hippocampus

Neuropsychiatric Disease and Treatment, 2018
Haiyan Jiao,1,* Zhiyi Yan,1,* Qingyu Ma,2 Xiaojuan Li,2 Youming Jiang,1 Yueyun Liu,1 Jiaxu Chen1,2 1School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China; 2Formula-Pattern Research Center, School of ...
Jiao H, Yan Z, Ma Q, Li X, Jiang Y, Liu Y, Chen J   +6 more
doaj  

The effect of dietary tryptophan supplementation, and an oral tryptophan challenge, on urinary excretion of 5-hydroxyindoleacetic acid in domestic dogs

Frontiers in Veterinary Science
Chronic enteropathies, commonly referred to as inflammatory bowel disease, are multi-factorial disorders that affect a substantial proportion of both the human population and companion animals.
Chloe Cheung, Jess Rigling, Bernadette Stang, Craig Ruaux   +3 more
doaj   +1 more source

THE EFFECT OF ADRENALECTOMY AND OF CORTISONE ADMINISTRATION ON THE METABOLISM OF l-TRYPTOPHAN

, 1956
F. Christine Brown, Clarence P. Berg
openalex   +1 more source

Effect of pyridoxine on the metabolism of tryptophan and branched-chain amino acids in two mentally retarded sibs. [PDF]

, 1966
A. F. Heeley, D. G. McCubbing, J. Shepherd   +2 more
openalex   +1 more source

SERS‐AI‐LUA‐Driven Salivary Diagnosis of Head and Neck Cancer Using Graphene‐Assisted Plasmonic Nanocorals

Advanced Science, EarlyView.
The developed graphene‐assisted plasmonic nanocoral platform enables sensitive, label‐free surface‐enhanced Raman scattering analysis of salivary metabolites for head and neck cancer (HNC) detection. When combined with machine learning classification and nonnegative least squares‐based spectral deconvolution, this approach achieves 98% diagnostic ...
Hyo Jeong Seo, Boyou Heo, Jun‐Yeong Yang, Rowoon Park, Sung‐Gyu Park, Jiyoung Yeo, So Hee Park, Chan Kwon Jung, Min‐Young Lee, Jooin Bang, Jun‐Ook Park, Ho Sang Jung   +11 more
wiley   +1 more source

Metabolic alterations in urine among the patients with severe fever with thrombocytopenia syndrome

Virology Journal
Background The pathogenesis of severe fever with thrombocytopenia syndrome (SFTS) remained unclear. We aimed to profile the metabolic alterations in urine of SFTS patients and provide new evidence for its pathogenesis.
Shan-Shan Zhang, Xin Yang, Wan-Xue Zhang, Yiguo Zhou, Ting-Ting Wei, Ning Cui, Juan Du, Wei Liu, Qing-Bin Lu   +8 more
doaj   +1 more source

Systematic Insights into the Relationship between the Microbiota–Gut–Brain Axis and Stroke with the Focus on Tryptophan Metabolism

Metabolites
Stroke, as a serious cerebral vascular disease with high incidence and high rates of disability and mortality, has limited therapeutic options due to the narrow time window.
Xinyu Shen, Xiaoqin Mu
doaj   +1 more source

Effect of treatment on the metabolism of tryptophan in childhood epilepsy. [PDF]

, 1967
Patricia A. Hughes, Bruce Bower, D. N. Raine, Nasreen A. Syed   +3 more
openalex   +1 more source