Results 121 to 130 of about 10,379 (248)
, 2017 Namen tega diplomskega dela je splošen pregled metabolizma triptofana in vpliv njegovih metabolitov na funkcije človeškega telesa. L-triptofan je ena od osmih esencialnih aminokislin, ki je človeško telo samo ne more sintetizirati,
Mejaš, Rok
core
Amino acids are crucial components of proteins, key molecules in cellular physiology and homeostasis. However, they are also involved in a variety of other mechanisms, such as energy homeostasis, nitrogen exchange, further synthesis of bioactive ...
Kajetan Kiełbowski +3 more
core +1 more source
Summary of tryptophan metabolism to indoleamines and auxin.
, 2019 Summary of tryptophan metabolism to indoleamines and auxin.
Praveen Saxena (3682132) +1 more
core +1 more source
SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition
Advanced Science, EarlyView.Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo +14 more
wiley +1 more source
RATEX: A Scalable RNA‐Based Platform for Logical and Multi‐Layered Cellular Programming
Angewandte Chemie, EarlyView.RATEX integrated ribosome‐mediated transcription control with synthetic RNA regulators, enabling simultaneous processing of RNA, metabolite, and small‐molecule inputs through complex logic operations within a single transcript. The platform achieves up to 1,492‐fold gene regulation, multi‐input hybrid logic gates, RNA‐programmed signaling cascades, and
Hyunseop Goh +3 more
wiley +2 more sources
Gut MicrobesEarly-life microbial metabolism of tryptophan plays a critical role in immune modulation and may influence susceptibility to inflammatory disorders such as eczema.
Naomi V. Wieser +12 more
doaj +1 more source
Regulation of tryptophan metabolism.
, 2013 Heat map showing the mean gene expression of the 18 genes in the KEGG pathway tryptophan metabolism, per group relative to the FM group. An asterisks(*) labelling the group indicates significant difference between the respective group and FM.
Felipe Eduardo Reveco (502785) +5 more
core +1 more source
Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression
Advanced Science, EarlyView.The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren +20 more
wiley +1 more source
Advances in Cancer Immunotherapy for Solid Tumors
Advanced Science, EarlyView.Cancer immunotherapy for solid tumors is rapidly evolving beyond classical checkpoint blockade toward more precise strategies. Emerging checkpoint targets, bispecific antibodies, antibody–drug conjugate combinations, personalized vaccines, cellular therapies, and engineered cytokines are expanding therapeutic possibilities, while biomarker‐guided ...
Shira Gabizon‐Peretz +1 more
wiley +1 more source