Results 121 to 130 of about 1,087,731 (295)

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Integrated analysis of bulk and single-cell RNA sequencing reveals the impact of nicotinamide and tryptophan metabolism on glioma prognosis and immunotherapy sensitivity

BMC Neurology
Background Nicotinamide and tryptophan metabolism play important roles in regulating tumor synthesis metabolism and signal transduction functions. However, their comprehensive impact on the prognosis and the tumor immune microenvironment of glioma is ...
Sen Wang, Shen Gao, Shaochong Lin, Xiaofeng Fang, Haopeng Zhang, Man Qiu, Kai Zheng, Yupeng Ji, Baijun Xiao, Xiangtong Zhang   +9 more
doaj   +1 more source

Tryptophan, phenylalanine and tyrosine metabolism.

, 2014
(A) Graphs represent the ScaledImpData of different biochemicals of the tryptophan metabolism from heart tissue samples. (B) Same as in A from plasma samples (C) A Graphs represent the ScaledImpData of different biochemicals of the phenylalanine and ...
Sofía Carbajosa (420515), Cristina Poveda (532456), Néstor A. Guerrero (284466), Carlos Chillón-Marinas (664070), Manuel Fresno (151573), Núria Gironès (284468)   +5 more
core   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Gut microbiota–derived tryptophan metabolites: molecular mechanisms, nutritional strategies and implications for swine health

Frontiers in Veterinary Science
Tryptophan, an essential amino acid, has nutritional value. Beyond that, it is an important signaling molecule that connects the gut microbiota with host physiology.
Yang Wen
doaj   +1 more source

A study of tryptophan metabolism in man.

, 1956
Tryptophan is one of the essential amino acids required by the mammalian body for protein anabolism. In recent years increasing interest has arisen in its intermediary metabolism.
Wiseman, Miriam. H.
core  

Inhibition of tryptophan metabolism by oestrogens in the rat: a factor in the aetiology of pellagra [PDF]

, 1984
The effect of the administration of oestrone sulphate on tryptophan metabolism has been assessed in rats in order to determine whether and to what extent inhibition of tryptophan metabolism by oestrogens may be a factor in the aetiology of pellagra, and ...
Bender, DA, Totoe, L
core  

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia

Advanced Science, EarlyView.
The gut microbiota organizes into two robust association patterns linked to colorectal neoplasia risk. Topological shifts in microbial networks are associated with metabolite alterations and may shape host responses during disease development. ABSTRACT Alterations of gut microbial communities impact health.
Kai Song, Youwen Qin, Jiahui Luo, Liping Liu, Chenyu Luo, Yinbin Qiu, Yiyi Zhong, Huanzi Zhong, Kui Wu, Meng Ni, Dong Wu, Min Dai, Shida Zhu, Hongda Chen   +13 more
wiley   +1 more source

The metabolism of tryptophan [PDF]

Biochemical Journal, 1924
openaire   +4 more sources