Results 271 to 280 of about 1,375,182 (353)

Medicine‐Food Plant Polysaccharides Modulate Diabetes and Diabetic Complications Through Maintaining Gut Function: A Review

Food Frontiers, EarlyView.
Polysaccharides derived from medicine‐food plants restore intestinal barrier integrity and microbiota balance while modulating short‐chain fatty acid levels. These modifications significantly alleviate diabetes and its complications, including nephropathy, retinopathy, cardiovascular disease, and neuropathy.
Yi Long, Wanglong Yu, Pingping Yang, Minxuan Xu, Jitao Ling, Yuting Wu, Xiao Liu, Liu Ouyang, Yan Xiong, Jianping Liu, Yiming Gan, Jing Zhang, Peng Yu, Deju Zhang   +13 more
wiley   +1 more source

Gut Microbial Tryptophan Metabolism Is Involved in Post-Cardiac Arrest Brain Injury via Pyroptosis Modulation. [PDF]

CNS Neurosci Ther
Wu C, Diao M, Yu S, Xi S, Zheng Z, Cao Y, Wang S, Zhu Y, Zhang M, Hu W.   +9 more
europepmc   +1 more source

Tea and Blood–Brain Barrier Homeostasis: Potential Mechanisms and Improvement Strategies

Food Frontiers, EarlyView.
Abstract The blood–brain barrier (BBB), a selective interface regulating cerebral substance exchange, plays a crucial role in maintaining cognitive function and metabolic balance. While tea consumption has been traditionally associated with health benefits, its specific effects on BBB integrity warrant systematic investigation. This review demonstrates
Rongbosen Yue, Haitao Wen, Lian He, Yan Liu, Zeng Liang, Liyong Luo   +5 more
wiley   +1 more source

Lactobacillus Plantarum 6C Alleviates DSS‐Induced Colitis via Ligilactobacillus Enrichment‐Dependent Suppression of the PI3K‐AKT Signaling Pathway

Food Frontiers, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic intestinal inflammatory disease with complex pathogenesis. Previous studies have shown that probiotics alleviate UC by modulating the gut microbiome. Therefore, this study aimed to investigate the ameliorative effect of Lactobacillus plantarum 6C (L.
Jiashan Qin, Jun Guo, Tieyun Chen, Ji'an Zhang, Wuyuntana, Shaoying Ma, Xinlei Yan   +6 more
wiley   +1 more source

Association between AHR in EGCs and IBS-D patients: the indole pathway of tryptophan metabolism. [PDF]

Front Nutr
Wang L, Zhang Y, Ran Y, Li L, Mei L, Ye F, Sun Y, Wang T, Quan X, Shi H, Dai F.   +10 more
europepmc   +1 more source

Integrative Evidence From Metabolome‐Wide Mendelian Randomization and Animal Models Implicates Tyrosine in Cardiac Hypercontractility and Arrhythmia Risk

Food Frontiers, EarlyView.
Plasma metabolome‐wide Mendelian randomization analysis established a causal link between tyrosine and arrhythmia. GWAS meta‐analysis identified tyrosine‐associated loci linked to cardiovascular risk factors. Animal studies confirmed that oral tyrosine intake modulates heart rhythm via adrenergic signaling activation.
Zhikang Cao, Huiying Liu, Peng Chen, Liyue Chen, Zhixin Chen, Jiaqiang Lin, Zixuan Fu, Zhipeng Li   +7 more
wiley   +1 more source

Antibiotic-Induced Dysbiosis of the Gut Microbiota Shifts Host Tryptophan Metabolism and Increases the Susceptibility of Mice to Pulmonary Infection With Pseudomonas aeruginosa. [PDF]

Immunology
de Brito CB, do Nascimento Arifa RD, de Oliveira Bezerra R, Dias Igídio CE, de Amorim-Santos BM, de Menezes Santos ACP, Barbosa LM, Barbosa JPP, Cassiano LMG, Kohlhoff M, Fagundes M, Batista RRÁ, Queiroz-Junior CM, Saliba AM, Raposo JDA, Braga FC, Coimbra RS, Teixeira MM, Fagundes CT, Souza DG.   +19 more
europepmc   +1 more source

Renoprotective Effect of Coix lachryma‐jobi L. Seed Polysaccharides in Adenine‐Induced Chronic Renal Failure by Blocking Gut Urea Metabolism

Food Frontiers, EarlyView.
ABSTRACT Dietary soluble fiber may alleviate renal damage in chronic kidney disease (CKD) by promoting intestinal urea excretion, though the underlying mechanisms remain unclear. This study investigated the digestion, fermentation, and renoprotective effects of Coix lachryma‐jobi L.
Hongmei Yin, Wanjun Liao, Yilian Huang, Qiang Hong, Na Zhang, Xiaodan Shi, Zongcai Tu, Hui Wang, Zuohua Xie, Tao Yuan   +9 more
wiley   +1 more source

Artemether and Euphorbia Factor L9 suppress kynurenine production through distinct effects on Tryptophan metabolism

Capatina AL, Czechowski T, Plunkett-Jones C, Tonon T, Kourtzelis I, Lichman BR, Brackenbury WJ, Graham IA, Lagos D.   +8 more
europepmc   +1 more source

Poly I:C-induced maternal immune activation causes schizophrenia-like behaviors in the offspring of both sexes by regulating gut microbiota and tryptophan metabolism pathway. [PDF]

Front Microbiol
Xu Z, Hu C, Luo Y.
europepmc   +1 more source