Results 271 to 280 of about 1,400,417 (341)

Lactobacillus regulate muscle fiber type conversion in Chinese native pigs via tryptophan metabolism. [PDF]

NPJ Biofilms Microbiomes
Song B, Azad MAK, Zhu Q, Cheng Y, Ding S, Yao K, Kong X.   +6 more
europepmc   +1 more source

Targeted metabolomics reveals dysregulated tryptophan metabolism in retinitis pigmentosa

Yijie Yang, Xue Han, Jiawei Shen, Ziwei Zhu, Peirong Lu   +4 more
openalex   +1 more source

Host‐driven hepatic conversion of gut microbiota‐derived putrescine to spermidine mediates mannose's protective effects against hepatic steatosis in zebrafish

iMeta, EarlyView.
Evidence for liver metabolism of gut‐derived microbial compounds into beneficial secondary metabolites has been lacking. Here, we demonstrate that Cetobacterium somerae (C. somerae), enriched by mannose supplementation under high‐fat diet conditions, convert arginine into putrescine.
Delong Meng, Zhen Zhang, Tsegay Teame, Benjamin Earl Niemann, Rui Xia, Shichang Xu, Yajie Zhao, Yalin Yang, Chao Ran, Le Luo Guan, Zhigang Zhou   +10 more
wiley   +1 more source

Epacadostat Overcomes Cetuximab Resistance in Colorectal Cancer by Targeting IDO-Mediated Tryptophan Metabolism. [PDF]

Cancer Sci
Zhou Y, Tao Q, Luo C, Chen J, Chen G, Sun J.   +5 more
europepmc   +1 more source

Metabolic Signatures and Diagnostic Prediction Models for Coronary Artery Disease and Type 2 Diabetes Mellitus: Insights From an Exploratory Study

iNew Medicine, EarlyView.
Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang, Meiming Su, Ying Li, Yapei Li, Shuo Chen, Ting Peng, Hans Strijdom, Jiangang Wang, Jianping Weng, Suowen Xu   +9 more
wiley   +1 more source

Multi-omics study reveals gut microbiota dysbiosis and tryptophan metabolism alterations in GH-PitNET progression. [PDF]

Sci Rep
Liu J, Ye Z, Zhang Y, You S, Sun S, Lu L, Su W, Liu J, Pu J, Pan H, Zhu H, Deng K, Yao Y, Hu X, Zhang S.   +14 more
europepmc   +1 more source

An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract

Journal of Applied Toxicology, EarlyView.
ABSTRACT Benzoxazinoids are secondary metabolites produced in monocotyledons and some dicotyledons from the Acanthaceae, Ranunculaceae, Scrophulariaceae, Plantaginaceae, and Lamiaceae families. Benzoxazinoids are commonly consumed in bread and cereal products that have been ingested for decades, which supports the safe use of benzoxazinoids as food ...
J. Kyle Weston, Barry S. Lynch, James A. Akingbasote   +2 more
wiley   +1 more source

Tryptophan metabolism: From physiological functions to key roles and therapeutic targets in cancer (Review). [PDF]

Oncol Rep
Zhao J, Bai X, Du J, Chen Y, Guo X, Zhang J, Gan J, Wu P, Chen S, Zhang X, Yang J, Jin J, Gao L.   +12 more
europepmc   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

Composite Probiotics Improve Gut Health and Enhance Tryptophan Metabolism in Nursery Piglets During Liquid Feeding. [PDF]

Int J Mol Sci
Du M, Zhang Q, Shen Y, Fu J, Wang Y, Yao B, Lu Z.   +6 more
europepmc   +1 more source