Results 161 to 170 of about 13,218 (205)

[Different immunological types of CRSwNP in the context of the new European EAACI nomenclature : Part 2: Hypersensitivity reactions of type V (epithelial barrier defects)]. [PDF]

open access: yesHNO
Klimek L   +17 more
europepmc   +1 more source

TSLP: from allergy to cancer

Nature Immunology, 2019
The cytokine TSLP has been shown to be a key factor in maintaining immune homeostasis and regulating inflammatory responses at mucosal barriers. While the role of TSLP in type 2 immune responses has been investigated extensively, recent studies have found an expanding role for TSLP in inflammatory diseases and cancer.
Jonathan Corren, Steven F. Ziegler
openaire   +2 more sources

TSLP: finally in the limelight

Nature Immunology, 2002
TSLP is now revealed to be an important regulator of DC-mediated control of TH2-based human allergic responses, identifying a potentially new species-specific function for this cytokine.
openaire   +1 more source

A possible role for TSLP in inflammatory arthritis

Biochemical and Biophysical Research Communications, 2007
Thymic stromal lymphopoietin (TSLP) is an IL-7-like cytokine that triggers dendritic cell-mediated Th2-type inflammatory responses and is considered as a master switch for allergic inflammation. In this study, we found increased levels of TSLP and, also TNF-alpha as previously reported, in synovial fluid specimens derived from patients with rheumatoid ...
Kensuke, Koyama   +14 more
openaire   +2 more sources

Novel Perspectives of TSLP and RXR Signaling in Corticosteroid-Resistant Asthma: Updates on TSLP Blockers

Current Medicinal Chemistry
Previous studies described that asthma patients who received corticosteroid therapy have been constrained by the corticosteroid resistance subsequently fostered to severe refractory asthma. In this review, we discussed the implications of TSLP, RXR, the role of STAT5-activating cytokines, and IL-33/NH-cell signaling pathways, and recent clinical ...
Song, Zhang   +17 more
openaire   +2 more sources

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