Results 1 to 10 of about 139,364 (204)
Thymic Stromal Lymphopoietin (TSLP), Its Isoforms and the Interplay with the Epithelium in Allergy and Asthma [PDF]
International Journal of Molecular Sciences, 2023 Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine that has emerged as a critical player in the development and progression of allergy and asthma. It is primarily produced by epithelial cells and functions as a potent immune system activator.
Dario Antolín-Amérigo +2 more
exaly +6 more sources
The Role of Thymic Stromal Lymphopoietin (TSLP) in Glomerulonephritis [PDF]
Childhood Kidney Diseases, 2018 Thymic stromal lymphopoietin (TSLP) is an interleukin-7-like cytokine that is an important trigger and initiator of many allergic diseases. TSLP promotes a T-helper type 2 (Th2) cytokine response that can be pathological. A relationship is formed both at
Keum Hwa Lee +8 more
doaj +8 more sources
Cloning of the Murine Thymic Stromal Lymphopoietin (Tslp) Receptor [PDF]
Journal of Experimental Medicine, 2000 The cellular receptor for murine thymic stromal lymphopoietin (TSLP) was detected in a variety of murine, but not human myelomonocytic cell lines by radioligand binding. cDNA clones encoding the receptor were isolated from a murine T helper cell cDNA library. TSLP receptor (TSLPR) is a member of the hematopoietin receptor family.
Werner Müller +2 more
exaly +4 more sources
Signal transduction around thymic stromal lymphopoietin (TSLP) in atopic asthma [PDF]
Cell Communication and Signaling, 2008 Thymic stromal lymphopoietin (TSLP), a novel interleukin-7-like cytokine, triggers dendritic cell-mediated inflammatory responses ultimately executed by T helper cells of the Th2 subtype.
Kuepper Michael +3 more
doaj +5 more sources
Regulation of Thymic Stromal Lymphopoietin (TSLP) receptor expression [PDF]
Allergy, Asthma & Clinical Immunology, 2010 Objective/purpose TSLP plays a major role in the induction and effector phases of allergic diseases by acting on dendritic cells, mast cells (MCs), T cells and CD34 hemopoietic progenitor cells. Whereas the cellular origin and the mechanisms regulating TSLP production are well documented, little is known about the regulation of TSLP receptor expression.
Allakhverdi Zoulfia, Delespesse Guy
doaj +3 more sources
Effects of Resveratrol on Thymic Stromal Lymphopoietin Expression in Mast Cells
Medicina, 2020 Background and objectives: Cytokine thymic stromal lymphopoietin (TSLP) plays a pivotal role in the pathogenesis of atopic diseases such as atopic dermatitis, allergic rhinitis, and asthma. Resveratrol (RSV) exerts various pharmacological effects such as
Phil-Dong Moon +6 more
doaj +2 more sources
TSLP and asthma: fellow travelers [PDF]
Exploration of Asthma & Allergy, 2023 The incidence of asthma, a heterogeneous inflammatory disease affecting over 300 million people worldwide, continues to increase in developed countries.
David El-Qutob, Antonio Letran
doaj +1 more source
The Role of TSLP in Atopic Dermatitis: From Pathogenetic Molecule to Therapeutical Target
Mediators of Inflammation, 2023 Atopic dermatitis (AD) is a kind of chronic skin disease with inflammatory infiltration, characterized by skin barrier dysfunction, immune response dysregulation, and skin dysbiosis.
Jialiang Luo +9 more
doaj +1 more source
Role of the TSLP and its Receptor in the Treatment of Asthma
Barcelona Respiratory Network Reviews, 2023 Thymic stromal lymphopoietin (TSLP) is a crucial cytokine in initiating and regulating immune responses. Various cell types, including epithelial cells, fibroblasts, and dendritic cells, synthesize TSLP. TSLP activates dendritic cells, which subsequently
Miguel Estravís +2 more
doaj +1 more source
The Biology of Thymic Stromal Lymphopoietin (TSLP) [PDF]
, 2013 Originally shown to promote the growth and activation of B cells, thymic stromal lymphopoietin (TSLP) is now known to have wide-ranging impacts on both hematopoietic and nonhematopoietic cell lineages, including dendritic cells, basophils, eosinophils, mast cells, CD4⁺, CD8⁺ and natural killer T cells, B cells and epithelial cells. While TSLP's role in
Steven F, Ziegler +5 more
openaire +2 more sources