The potential role of interleukin (IL)‐25/IL‐33/thymic stromal lymphopoietin (TSLP) on the pathogenesis of idiopathic pulmonary fibrosis [PDF]
The Clinical Respiratory Journal, 2022 Objectives Interleukin (IL)‐25, IL‐33, and thymic stromal lymphopoietin (TSLP) are the important drivers for excessive type‐2 immunity. It has been well elucidated that IL‐25/IL‐33/TSLP plays an important role in allergic airway inflammation and ...
Xuefeng Xu, Huaping Dai, Jinglan Zhang
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Fine Particulate matter (PM2.5) is a risk factor for dermatitis by promoting the expression of thymic stromal lymphopoietin (TSLP) in keratinocytes [PDF]
Indian Journal of Dermatology, 2020 Aim: Common indoor pollutants, as fine particulate matter (PM2.5), can damage people's health and cause skin allergies. However, it remains unknown which common pollutants can lead to allergy, such as, in children atopic dermatitis, and what is the key ...
Fei Li +4 more
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Thymic Stromal Lymphopoietin (TSLP), Its Isoforms and the Interplay with the Epithelium in Allergy and Asthma [PDF]
International Journal of Molecular Sciences, 2023 Dario Antolín-Amérigo +2 more
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TSLP and asthma: fellow travelers [PDF]
Exploration of Asthma & Allergy, 2023 The incidence of asthma, a heterogeneous inflammatory disease affecting over 300 million people worldwide, continues to increase in developed countries.
David El-Qutob, Antonio Letran
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Effects of Resveratrol on Thymic Stromal Lymphopoietin Expression in Mast Cells
Medicina, 2020 Background and objectives: Cytokine thymic stromal lymphopoietin (TSLP) plays a pivotal role in the pathogenesis of atopic diseases such as atopic dermatitis, allergic rhinitis, and asthma. Resveratrol (RSV) exerts various pharmacological effects such as
Phil-Dong Moon +6 more
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The Role of TSLP in Atopic Dermatitis: From Pathogenetic Molecule to Therapeutical Target
Mediators of Inflammation, 2023 Atopic dermatitis (AD) is a kind of chronic skin disease with inflammatory infiltration, characterized by skin barrier dysfunction, immune response dysregulation, and skin dysbiosis.
Jialiang Luo +9 more
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Role of the TSLP and its Receptor in the Treatment of Asthma
Barcelona Respiratory Network Reviews, 2023 Thymic stromal lymphopoietin (TSLP) is a crucial cytokine in initiating and regulating immune responses. Various cell types, including epithelial cells, fibroblasts, and dendritic cells, synthesize TSLP. TSLP activates dendritic cells, which subsequently
Miguel Estravís +2 more
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Thymic Stromal Lymphopoietin and Cancer: Th2-Dependent and -Independent Mechanisms
Frontiers in Immunology, 2020 The thymic stromal lymphopoietin (TSLP) is an IL-7-like cytokine originally cloned from a murine thymic stromal cell line, and subsequently a human homolog was identified using database search methods.
Maria Pia Protti +3 more
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TSLP activates the production of IFN-γ via CD8-positive T cells in recurrent tonsillitis
Clinical Immunology Communications, 2022 The role of thymic stromal lymphopoietin (TSLP) in chronic infection is not well understood. We report an increased number of cluster of differentiation 8 (CD8+ T) cells and higher expression of TSLP in the tonsil tissues of patients with recurrent ...
Kota Hiraoka +5 more
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Thymic Stromal Lymphopoietin: To Cut a Long Story ShortSummary
Cellular and Molecular Gastroenterology and Hepatology, 2017 Thymic stromal lymphopoietin (TSLP) was identified more than 20 years ago as a secreted factor of a mouse thymic stromal cell line; later, a human orthologue was also identified.
Katerina Tsilingiri +2 more
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