Results 31 to 40 of about 152,280 (211)

The role of thymic stromal lymphopoietin (TSLP) in allergic disorders [PDF]

Current Opinion in Immunology, 2010
The importance of the epithelium in initiating and controlling immune responses is becoming more appreciated. For example, allergen contact first occurs at mucosal sites exposed to the external environment, such as the skin, airways and gastrointestinal tract.
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A novel xenograft model to study the role of TSLP-induced CRLF2 signals in normal and malignant human B lymphopoiesis

Haematologica, 2016
Thymic stromal lymphopoietin (TSLP) stimulates in vitro proliferation of human fetal B-cell precursors. However, its in vivo role during normal human B lymphopoiesis is unknown.
Olivia L. Francis, Terry-Ann M. Milford, Shannalee R. Martinez, Ineavely Baez, Jacqueline S. Coats, Karina Mayagoitia, Katherine R. Concepcion, Elizabeth Ginelli, Cornelia Beldiman, Abigail Benitez, Abby J. Weldon, Keshav Arogyaswamy, Parveen Shiraz, Ross Fisher, Christopher L. Morris, Xiao-Bing Zhang, Valeri Filippov, Ben Van Handel, Zheng Ge, Chunhua Song, Sinisa Dovat, Ruijun Jeanna Su, Kimberly J. Payne   +22 more
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TSLP is involved in expansion of early thymocyte progenitors

BMC Immunology, 2007
Background Thymic stromal derived lymphopoietin (TSLP) is preferentially and highly expressed in the thymus, but its function in T cell development is not clear.
Coffield V McNeil, Jiang Qi, Kondo Motonari, Su Lishan   +3 more
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Thymic stromal lymphopoietin limits primary and recall CD8+ T-cell anti-viral responses

eLife, 2021
Thymic stromal lymphopoietin (TSLP) is a cytokine that acts directly on CD4+ T cells and dendritic cells to promote progression of asthma, atopic dermatitis, and allergic inflammation.
Risa Ebina-Shibuya, Erin E West, Rosanne Spolski, Peng Li, Jangsuk Oh, Majid Kazemian, Daniel Gromer, Phillip Swanson, Ning Du, Dorian B McGavern, Warren J Leonard   +10 more
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Peripheral blood TSLP (thymic stromal lymphopoietin) in children as a biomarker?

Paediatric asthma and allergy, 2021
Introduction There is substantial evidence that alarmin TSLP plays one of the key roles in driving type 2 inflammation and it is also thought that it has a role in neutrophilic, type 2-low airway inflammation. There is much less known about the role of alarmins in type 2-low asthma and its role in the heterogeneity of inflammation in acute asthma ...
Vrsalovic, Renata, Korosec, Peter, Stojkovic, Urska Bidovec, Stefanovic, Iva Mihatov, Cicak, Biserka, Samija, Ivan, Skrgat, Sabina   +6 more
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A Comparison for Type 2 Cytokines and Lesional Inflammatory Infiltrations in Bullous Pemphigoid and Atopic Dermatitis

Clinical, Cosmetic and Investigational Dermatology, 2022
Yu-qing Hu, Jian-zhong Zhang Department of Dermatology, Peking University People’s Hospital, Beijing, People’s Republic ChinaCorrespondence: Jian-zhong Zhang, Tel +86-10-88325472, Fax +86-10-68318386, Email rmzjz@126.comBackground: Bullous pemphigoid (BP)
Hu YQ, Zhang JZ
doaj  

Thymic Stromal Lymphopoietin in Cutaneous Immune-Mediated Diseases

Frontiers in Immunology, 2021
Thymic stromal lymphopoietin (TSLP) was initially demonstrated to be critical in regulating inflammatory responses among various allergic disorders (such as atopic dermatitis, food allergy, and asthma). Although two isoforms (short form and long form) of
Si-Hang Wang, Ya-Gang Zuo
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Functional characterisation of two receptor interaction determinants in human thymic stromal lymphopoietin

, 2021
Thymic stromal lymphopoietin (TSLP) is a pro-inflammatory cytokine with important pathological roles in Asthma bronchiale, malignant tumours and other diseases.
Marković, Iva, Friedrich, Karlheinz, Gautam, Kritan, Wolfrum, Therese, Wohlmann, Andreas, Therese Wolfrum, Iva Marković, Andreas Wohlmann, Kritan Gautam, Karlheinz Friedrich   +9 more
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Inhibition of Virus-Induced Cytokine Production from Airway Epithelial Cells by the Late Addition of Budesonide

Medicina, 2020
Background: Viral infection is the main cause of asthma and COPD (chronic obstructive pulmonary disease) exacerbation and accumulate inflammatory cells to airway tissue.
Tetsuya Homma, Yosuke Fukuda, Yoshitaka Uchida, Tomoki Uno, Megumi Jinno, Yasunari Kishino, Mayumi Yamamoto, Hiroki Sato, Kaho Akimoto, Keisuke Kaneko, Akiko Fujiwara, Haruna Sato, Kuniaki Hirai, Yoshito Miyata, Hideki Inoue, Shin Ohta, Yoshio Watanabe, Sojiro Kusumoto, Koichi Ando, Shintaro Suzuki, Toshimitsu Yamaoka, Akihiko Tanaka, Tohru Ohmori, Hironori Sagara   +23 more
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Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps

, 2012
Thymic stromal lymphopoietin (TSLP) that is released by epithelial cells upon certain environmental triggers activates cells of the innate and adaptive immune system resulting in a preferential T helper 2 immune response.
Simon, H-U, S. Yousefi, Simon, D, Yousefi, S, Stöckle, C, H.-U. Simon, M. Morshed, C. Stöckle, D. Simon, Morshed, M, Stöckle C, Yousefi S, Yousefi, Shida, Simon HU, Simon, Hans-Uwe, Morshed M, Morshed, Md. Mahbubul, Simon D, Simon, Dagmar   +18 more
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