Results 191 to 200 of about 22,102 (233)

Progress in research on predictors of adverse outcomes in patients with nasal inflammatory diseases. [PDF]

Front Immunol
Liao JX, Lin X, He J, Feng HJ, Liang ZP, Qin G.   +5 more
europepmc   +1 more source

Feasibility of Treating Eosinophilic Chronic Rhinosinusitis Using Short-Chain Fatty Acids. [PDF]

Laryngoscope
Gozawa R, Imoto Y, Sonoda Y, Maegawa A, Shimizu A, Kidoguchi M, Koyama K, Adachi N, Morikawa T, Miyazaki Y, Saito K, Sakashita M, Fujieda S.   +12 more
europepmc   +1 more source

Tuft cell cysteinyl leukotrienes are necessary for rhinovirus-induced mucus metaplasia, type 2 inflammation and airway hyperresponsiveness in immature mice. [PDF]

Front Immunol
Parker DT, Bentley JK, Lei J, Domala B, Briggs HL, Singh S, Li Y, Reiner MC, Flores DA, Sliwicki AL, Flori HR, Hershenson MB.   +11 more
europepmc   +1 more source

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TSLP: from allergy to cancer

Nature Immunology, 2019
The cytokine TSLP has been shown to be a key factor in maintaining immune homeostasis and regulating inflammatory responses at mucosal barriers. While the role of TSLP in type 2 immune responses has been investigated extensively, recent studies have found an expanding role for TSLP in inflammatory diseases and cancer.
Jonathan Corren, Steven F Ziegler
exaly   +3 more sources

TSLP disease-associated genetic variants combined with airway TSLP expression influence asthma risk

Journal of Allergy and Clinical Immunology, 2022
Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine important in initiation of allergic inflammation. Single nucleotide polymorphisms (SNPs) in TSLP are associated with asthma, yet studies have shown inconsistent associations between circulating TSLP and asthma.
Liza Bronner, Murrison, Xiaomeng, Ren, Kristina, Preusse, Hua, He, John, Kroner, Xiaoting, Chen, Seth, Jenkins, Elisabet, Johansson, Jocelyn M, Biagini, Matthew T, Weirauch, Raphael, Kopan, Lisa J, Martin, Gurjit K, Khurana Hershey   +12 more
openaire   +2 more sources

Thymic stromal lymphopoietin (TSLP) and Toluene-diisocyanate-induced airway inflammation: Alleviation by TSLP neutralizing antibody

Toxicology Letters, 2019
Toluene-diisocyanate (TDI) is mainly used in the manufacturing process of polyurethane foams, and is a potent inducer of occupational asthma characterized by airway inflammation and airway hyperreactivity. Thymic stromal lymphopoietin (TSLP) plays an important role in the development of asthma, and correlating with the differentiation of Th2 and Th17 ...
Gongchang Yu, Yu Zhang, Xiaoqun Wang, Linlin Sai, Cunxiang Bo, Abrey J. Yeo, Martin F. Lavin, Cheng Peng, Qiang Jia, Hua Shao   +9 more
openaire   +3 more sources

TSLP: finally in the limelight

Nature Immunology, 2002
TSLP is now revealed to be an important regulator of DC-mediated control of TH2-based human allergic responses, identifying a potentially new species-specific function for this cytokine.
openaire   +1 more source

IL-7 and TSLP receptors: twisted sisters

Blood, 2014
In this issue of Blood, Shochat et al report mutations in receptors for interleukin-7 (IL-7) and thymic stromal lymphopoietin (TSLP), resulting in a novel dimerization mechanism that drives acute lymphoblastic leukemias.
openaire   +2 more sources

Novel Perspectives of TSLP and RXR Signaling in Corticosteroid-Resistant Asthma: Updates on TSLP Blockers

Current Medicinal Chemistry
Previous studies described that asthma patients who received corticosteroid therapy have been constrained by the corticosteroid resistance subsequently fostered to severe refractory asthma. In this review, we discussed the implications of TSLP, RXR, the role of STAT5-activating cytokines, and IL-33/NH-cell signaling pathways, and recent clinical ...
Song Zhang, Karen Dsouza, Narasimha Murthy Beeraka, Junqi Liu, Oksana Reshetniak, Hemanth Vikram Poola Ramachandrappa, Lal Gowri Priyanka, Greeshma Mandya Venkata, Shalini Hassan Doreswamy, Pradeep Kumar Bhupalam, Mahesh Padukudru Anand, Prasath Manogaran, Rajashree Deka, Gurupadayya Bannimath, Mikhail Yegorovich Sinelnikov, Vladimir Nikolaevich Nikolenko, Kirill Vladimirovich Bulygin, Ruitai Fan   +17 more
openaire   +2 more sources