Results 221 to 230 of about 161,769 (302)

Increasing Filamins A and B in Th2 Lymphocytes as a Therapeutic Opportunity to Attenuate Airway Inflammation in Mice. [PDF]

open access: yesAllergy
Chamy L   +7 more
europepmc   +1 more source

Temporal Patterns in Preterm Birth Subtypes and Perinatal Survival, 2000–2023: Population‐Based, Repeated Cross‐Sectional Time‐Series

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 6, Page 1213-1226, May 2026.
ABSTRACT Objective Evaluate the rate and trend of preterm birth (PTB) and the associated perinatal survival in Hong Kong. Design Population‐based, repeated cross‐sectional time series. Setting All public maternity hospitals. Population 845 640 singleton and 26 748 twin deliveries from 2000 to 2023.
Ka Wang Cheung   +11 more
wiley   +1 more source

From “Passive Supplementation” to “Active Repair”: Melatonin Reshapes the Treatment Paradigm for Late‐Onset Hypogonadism by Targeting Leydig Cell Senescence

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu   +6 more
wiley   +1 more source

Histone Deacetylase 9 Gene Deletion Ameliorates Aging‐Related Adipose Tissue Senescence and Mitochondrial Dysfunction in Mice

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Cellular senescence and mitochondrial dysfunction disrupt adipose tissue homeostasis during aging, but mechanisms remain unclear. HDAC9 expression increases with age in mouse adipose tissue and Hdac9 knockout mice showed reduced fat mass, senescence markers, and enhanced mitochondrial gene expression, respiration, and thiosulfate sulfurtransferase (Tst)
Brandee Goo   +15 more
wiley   +1 more source

Age Does Not Affect Respiratory Characteristics in Children With Prader‐Willi Syndrome Before and After Growth Hormone Therapy

open access: yesActa Paediatrica, Volume 115, Issue 5, Page 1106-1115, May 2026.
ABSTRACT Aim Children with Prader‐Willi syndrome (PWS) are at increased risk of both central (CSA) and obstructive sleep apnoea (OSA). Studies examining the effects of growth hormone have focused on older children; however, therapy is often initiated before the age of 2 years.
Michelle Ip   +7 more
wiley   +1 more source

Future direction of tuberculin skin test: Integration of telemedicine for test reading. [PDF]

open access: yesDigit Health
Yigit N   +4 more
europepmc   +1 more source

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 2099-2122, May 2026.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata   +13 more
wiley   +1 more source

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