Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
Direct or indirect: the crucial role of N-palmitate in hedgehog signaling. [PDF]
Puschmann J, Grobe K.
europepmc +1 more source
Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley +1 more source
Total Sealing Technique Using an Advanced Bipolar Vessel-Sealing System in Axillary Lymph Node Dissection: A Technical Note and Review of Clinical and Economic Outcomes. [PDF]
Ikeda N +4 more
europepmc +1 more source
This study identifies the metabolic score for insulin resistance (METS‐IR) as an independent predictor of hypertension and resistant hypertension in obstructive sleep apnea (OSA). Crucially, this dose–response relationship is robust in severe OSA but attenuated in non‐severe cases, highlighting METS‐IR as a practical biomarker for risk stratification ...
Jinwei Xin +5 more
wiley +1 more source
Exploring the associations between physical activity, sleep, sedentary behaviour, and mental health in young German children. [PDF]
Osojnicki K +5 more
europepmc +1 more source
S3‐Leitlinie Diagnostik und Therapie der Alopecia areata – Teil 1: Diagnostik und Epidemiologie
Zusammenfassung In dem vom Innovationsausschuss beim gemeinsamen Bundesausschuss (G‐BA) geförderten Projekt wurde von 2023 bis 2025 die S3‐Leitlinie zur Diagnostik und Therapie der Alopecia areata (AA) entwickelt. Die interdisziplinäre Expertengruppe bestand aus Vertretern der Deutschen Dermatologischen Gesellschaft, insbesondere aus der AG ...
Ulrike Blume‐Peytavi +13 more
wiley +1 more source
Responding to a protracted tuberculosis outbreak: lessons from multiple rounds of investigation in a Chinese boarding school. [PDF]
Mao J +9 more
europepmc +1 more source
S3 guideline diagnostics and therapy of alopecia areata – Part 1: Diagnostics and epidemiology
Summary In the project funded by the Innovation Committee at the G‐BA, the S3 guideline for the diagnosis and treatment of AA was developed between 2023 and 2025. The interdisciplinary expert panel consisted of representatives from the German Dermatological Society, in particular from the Pediatric Dermatology Working Group, the Professional ...
Ulrike Blume‐Peytavi +13 more
wiley +1 more source

