Results 191 to 200 of about 56,272 (223)

Chemical properties and biological activities of three highly purified major tetrodotoxin analogues. [PDF]

open access: yesProc Jpn Acad Ser B Phys Biol Sci
Yotsu-Yamashita M   +7 more
europepmc   +1 more source

Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons. [PDF]

open access: yesNat Commun
Kroll J   +9 more
europepmc   +1 more source
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TTX accumulation in pufferfish

Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 2006
Tetrodotoxin (TTX) has been detected in a variety of animals. The finding of TTX in the trumpet shell Charonia sauliae strongly suggested that its origin was its food, a TTX-bearing starfish Astropecten polyacanthus. Since then, the food chain has been consistently implicated as the principal means of TTX intoxication.
Osamu Arakawa, Tomohiro Takatani
exaly   +3 more sources

A Mutant of TTX-Resistant Cardiac Sodium Channels with TTX-Sensitive Properties

Science, 1992
The cardiac sodium channel α subunit (RHI) is less sensitive to tetrodotoxin (TTX) and saxitoxin (STX) and more sensitive to cadmium than brain and skeletal muscle (μl) isoforms. An RHI mutant, with Tyr substituted for Cys at position 374 (as in μl) confers three properties of TTX-sensitive channels: (i) greater sensitivity to TTX (730-fold); (ii ...
Jonathan Satin
exaly   +3 more sources

Inactivation of TTX-sensitive and TTX-insensitive sodium channels of rat myoballs

Neuroscience Letters, 1987
Myoballs, spherical muscle cell regenerates, have two types of Na+ channels, the adult type with a high sensitivity to the Na+ channel blocker tetrodotoxin (TTX), and the juvenile type with 10 times less TTX sensitivity. The potential dependence of the steady-state inactivation of the Na+ channels (h infinity-curve) was studied in 50 rat myoballs with ...
J P, Ruppersberg, A, Schure, R, Rüdel
openaire   +2 more sources

‘G.A.T.E’: Gap analysis for TTX evaluation

AIP Conference Proceedings, 2016
A Table Top Exercise (TTX) gap analysis tool was developed with the aim to provide a complete, systematic and objective evaluation of TTXs organized in safety and security fields. A TTX consists in a discussion-based emergency management exercise, organized in a simulated emergency scenario, involving groups of players who are subjected to a set of ...
CACCIOTTI, ILARIA   +7 more
openaire   +2 more sources

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