DDT exposure induces microglial activation and disease-associated microglial signatures: Relevance to mechanisms of Alzheimer's disease. [PDF]
Mhatre-Winters I +6 more
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Chemical properties and biological activities of three highly purified major tetrodotoxin analogues. [PDF]
Yotsu-Yamashita M +7 more
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Targeting CD39 as a Therapeutic for Cancer Immunotherapy. [PDF]
Li Z, Xu W, Kwok HF.
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Neurons of the precuneiform nucleus share structural and functional properties of the mesencephalic locomotor region. [PDF]
Pocsai K +5 more
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Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons. [PDF]
Kroll J +9 more
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TTX accumulation in pufferfish
Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 2006Tetrodotoxin (TTX) has been detected in a variety of animals. The finding of TTX in the trumpet shell Charonia sauliae strongly suggested that its origin was its food, a TTX-bearing starfish Astropecten polyacanthus. Since then, the food chain has been consistently implicated as the principal means of TTX intoxication.
Osamu Arakawa, Tomohiro Takatani
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A Mutant of TTX-Resistant Cardiac Sodium Channels with TTX-Sensitive Properties
Science, 1992The cardiac sodium channel α subunit (RHI) is less sensitive to tetrodotoxin (TTX) and saxitoxin (STX) and more sensitive to cadmium than brain and skeletal muscle (μl) isoforms. An RHI mutant, with Tyr substituted for Cys at position 374 (as in μl) confers three properties of TTX-sensitive channels: (i) greater sensitivity to TTX (730-fold); (ii ...
Jonathan Satin
exaly +3 more sources
Inactivation of TTX-sensitive and TTX-insensitive sodium channels of rat myoballs
Neuroscience Letters, 1987Myoballs, spherical muscle cell regenerates, have two types of Na+ channels, the adult type with a high sensitivity to the Na+ channel blocker tetrodotoxin (TTX), and the juvenile type with 10 times less TTX sensitivity. The potential dependence of the steady-state inactivation of the Na+ channels (h infinity-curve) was studied in 50 rat myoballs with ...
J P, Ruppersberg, A, Schure, R, Rüdel
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‘G.A.T.E’: Gap analysis for TTX evaluation
AIP Conference Proceedings, 2016A Table Top Exercise (TTX) gap analysis tool was developed with the aim to provide a complete, systematic and objective evaluation of TTXs organized in safety and security fields. A TTX consists in a discussion-based emergency management exercise, organized in a simulated emergency scenario, involving groups of players who are subjected to a set of ...
CACCIOTTI, ILARIA +7 more
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