Optimization of a molecularly defined tuberculin formulation: recombinant fusion proteins and epitope surgery [PDF]
Bovine tuberculosis is an infectious livestock disease of global economic and zoonotic importance. Surveillance programs are largely dependent on the skin test that utilizes purified protein derivatives (PPDs) of tuberculin.
Sonya Middleton +8 more
doaj +2 more sources
Development and evaluation of a formaldehyde-stabilized tuberculin as a safe and potent alternative to phenol-based purified protein derivative for the diagnosis of animal tuberculosis [PDF]
Background and Aim: Bovine tuberculosis (bTB), caused by Mycobacterium bovis, remains a significant zoonotic threat to livestock and public health, resulting in major economic losses.
Kairat Turgenbayev +5 more
doaj +2 more sources
Exploring the Fate of Cattle Herds With Inconclusive Reactors to the Tuberculin Skin Test [PDF]
Bovine tuberculosis (TB) is an important animal health issue in many parts of the world. In England and Wales, the primary test to detect infected animals is the single intradermal comparative cervical tuberculin test, which compares immunological ...
Lucy A. Brunton +4 more
doaj +5 more sources
Natural variation in immune responses to neonatal mycobacterium bovis bacillus calmette-guerin (BCG) vaccination in a cohort of Gambian infants [PDF]
Background There is a need for new vaccines for tuberculosis (TB) that protect against adult pulmonary disease in regions where BCG is not effective.
A Lalvani +46 more
core +41 more sources
Background and Objectives: Glanders is a serious zoonotic disease caused by Burkholderia mallei. Prevention, control, and treatment strategies of glanders are prerequisites for microbial source tracking. The present study was aimed to analyze the genomic
Shojaat Dashtipour +4 more
doaj +1 more source
The age-specific burden and household and school-based predictors of child and adolescent tuberculosis infection in rural Uganda. [PDF]
BackgroundThe age-specific epidemiology of child and adolescent tuberculosis (TB) is poorly understood, especially in rural areas of East Africa. We sought to characterize the age-specific prevalence and predictors of TB infection among children and ...
Atukunda, Mucunguzi +14 more
core +2 more sources
Tuberculin reactivity in schoolchildren, Kassala State, Sudan
Background: Tuberculin skin test (TST) is widely used for the assessment of Bacillus Calmette–Guérin (BCG) vaccine efficacy and screening of latent TB infection (LTBI). Poor or no data are available on the reactivity of tuberculin in Kassala State.
Fatima Abbas Khalid +3 more
doaj +1 more source
Screening for Tuberculosis in Health Care Workers. Experience in an Italian Teaching Hospital [PDF]
Health care workers (HCW) are particularly at risk of acquiring tuberculosis (TB), even in countries with low TB incidence. Therefore, TB screening in HCW is a useful prevention strategy in countries with both low and high TB incidence.
De Luca, Assunta +8 more
core +3 more sources
Background. Correct identification of individuals with latent tuberculosis infection (LTBI) is a crucial element of the elimination strategy, allowing their adequate treatment.
L.R. Codecasa +8 more
doaj +1 more source
Robert Koch’s Professional and Personal Life
All creative people, whose names we remember, are united by such a character trait as passion. And the field of creativity is not so important here — both in art, and in technical sciences, and in medicine, to achieve a result, complete immersion in ...
G. V. Maksimov +3 more
doaj +1 more source

