Results 101 to 110 of about 828,953 (227)
This study compares the biomechanical effects of three anterior fixation systems in thoracolumbar surgery—HXTL, NHXTL, and Medtronic's CD Horizon ANTERIOR. Finite element analysis evaluates stress and displacement across vertebral bodies and support structures under varying load conditions. Results indicate the HXTL system minimizes nail–rod stress yet
Xuehai Jia +7 more
wiley +1 more source
B Cell and Antibody Responses in Bovine Tuberculosis
The development of vaccines and effective diagnostic methods for bovine tuberculosis requires an understanding of the immune response against its causative agent, Mycobacterium bovis.
Laura Inés Klepp +6 more
doaj +1 more source
Tuberculosis is the most important zoonotic bacterial disease that is hazardous to both man and animals. A huge economic loss which could be direct or indirect is associated with the disease, so rapid diagnostic tests for tuberculosis are needed to ...
Nasr E.A. +4 more
doaj +1 more source
Identification of Novel Antigens Recognized by Serum Antibodies in Bovine Tuberculosis
Bovine tuberculosis (TB), caused by Mycobacterium bovis, remains an important zoonotic disease posing a serious threat to livestock and wildlife. The current TB tests relying on cell-mediated and humoral immune responses in cattle have performance ...
K. Lyashchenko +14 more
semanticscholar +1 more source
De Novo Design and Synthesis of Novel Benzoxazinone Derivatives Targeting Dihydroxyacid Dehydratase
ABSTRACT Dihydroxyacid dehydratase (DHAD), a key enzyme in the branched‐chain amino acid (BCAA) synthesis pathway, is a promising herbicide target. Currently, no commercial herbicides target DHAD, and no inhibitors are in development. Structural analysis suggests that coordination with iron–sulfur clusters and hydrophobic interactions with Tyr215 and ...
Bo He +7 more
wiley +1 more source
Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco +24 more
wiley +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Bovine tuberculosis is yet a major public health problem throughout the world, including African countries like Ethiopia. Limited public knowledge about the disease, coupled with negative attitudes and poor health practices, are contributing to this ...
Asrat Solomon Kenasew +3 more
doaj +2 more sources
: Bovine tuberculosis (BTB) is a chronic infectious disease caused by Mycobacterium bovis . This disease is widely distributed throughout the world and mainly affects animals with occasional human involvement.
T. Belachew
semanticscholar +1 more source

