Results 71 to 80 of about 127,769 (266)

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: the Randomized, Phase 3, TULIP‐SC Study

Arthritis &Rheumatology, Accepted Article.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate‐to‐severe SLE activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly for 52 weeks (1:1 ...
Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, The TULIP‐SC investigators   +12 more
wiley   +1 more source

Causes of death and associated factors over a decade of follow-up in a cohort of people living with HIV in rural Tanzania

BMC Infectious Diseases, 2022
Background Nearly half of HIV-related deaths occur in East and Southern Africa, yet data on causes of death (COD) are scarce. We determined COD and associated factors among people living with HIV (PLHIV) in rural Tanzania.
Getrud Joseph Mollel, Lilian Moshi, Hoda Hazem, Anna Eichenberger, Olivia Kitau, Herry Mapesi, Tracy R. Glass, Daniel Henry Paris, Maja Weisser, Fiona Vanobberghen   +9 more
doaj   +1 more source

Comprehensive cardiovascular magnetic resonance for monitoring the response to therapy in pericardial tuberculosis [PDF]

European Heart Journal - Cardiovascular Imaging, 2013
A Caucasian 25-year-old man with cardiac tamponade underwent urgent pericardiocentesis with the removal of 100 ml of siero-ematic essudative fluid. Smear microscopy detected acid-fast bacilli, and pericardial tuberculosis was confirmed by positive culture for Mycobacterium tuberculosis.
Chrysanthos, Grigoratos, Massimiliano, Mariani, Andrea, Barison, Massimo, Lombardi, Pier Giorgio, Masci   +4 more
openaire   +2 more sources

The unavoidable costs of ethnicity : a review of evidence on health costs [PDF]

, 1999
This report was commissioned by the Advisory Committee on Resource Allocation (ACRA), and prepared by the Centre for Health Services Studies (CHESS) and the Centre for Research in Ethnic Relations (CRER) at the University of Warwick.
Clark, M. D. (Michael D.), Johnson, Mark R. D., Owen, David, Szczepura, Ala   +3 more
core  

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Reduced Phagocytic Capacity of Blood Monocyte/Macrophages in Tuberculosis Patients Is Further Reduced by Smoking. [PDF]

, 2016
Tuberculosis (TB) and tobacco use are two major alarming global health issues posing immense threats to human populations. Mycobacterium tuberculosis (MTB) by activation of macrophages could induce the sequences of cells activation and releases of ...
Adcock, IM, Aryanpur, M, Garssen, J, Masjedi, MR, Mortaz, E, Mozafarian, A, Sharifi, H, Tabarsi, P   +7 more
core   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

Cardiovascular Involvement in Tuberculosis Patients Treated in Southern Africa

JACC: Advances
Background Tuberculosis (TB) is the leading cause of death among people with HIV and a major global health challenge. Subclinical cardiovascular manifestations of TB are poorly documented in high TB and HIV burden countries. Objectives The purpose of this study was to quantify the prevalence of cardiovascular involvement in TB patients and investigate ...
Samim, Daryoush, Muula, Guy, Banholzer, Nicolas, Chibomba, Douglas, Xulu, Sihle, Bolton, Carolyn, Evans, Denise, Perrig, Lisa, De Marchi, Stefano, Günther, Gunar, Egger, Matthias, Pilgrim, Thomas, Fenner, Lukas Antoine   +12 more
openaire   +3 more sources