Results 141 to 150 of about 110,366 (252)
Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley +1 more source
We report a 63‐year‐old man with active pulmonary tuberculosis who developed drug‐induced fever after commencing standard anti‐TB therapy. Sequential and additive drug challenge identified rifampicin as the offending agent. The patient subsequently underwent successful rapid oral rifampicin desensitization in an outpatient setting, enabling completion ...
Xin Yue Guo, Constantine Zois
wiley +1 more source
Surgical correction of a double congenital hernia in a veal calf
Abstract This clinical case report describes the rare occurrence and successful surgical management of two simultaneous congenital hernias, umbilical and perineal, in a crossbred veal calf. At 5 days of age, the animal, weighing approximately 40 kg, showed visible swelling in the umbilical and perineal regions together with a congenital tail ...
Andrea Spadaro +4 more
wiley +1 more source
Why Is MS a More Frequent Complication of EBV Infection in Females?
ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn +2 more
wiley +1 more source
Lower extremity weakness: A rare case of extrapulmonary tuberculosis [PDF]
Adhikari, Sunil +2 more
core +1 more source
Candida Drug Resistance in Patients With Diabetic Foot Ulcers: A Systematic Review and Meta‐Analysis
ABSTRACT Diabetic foot ulcers (DFUs) are one of the most serious and common complications that, if not treated properly, can lead to potential damage and even amputation. The aim of this systematic review and meta‐analysis was to assess the drug‐resistant Candida species in DFU.
Mohammad Hossein Ekvan +7 more
wiley +1 more source
Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years
The current study found no evidence of cumulative increased safety risks with upadacitinib 15 or 30 mg for up to 6 years and over 9000 patient‐years of safety data in adults and adolescents. There were low rates of adjudicated major adverse cardiovascular events, adjudicated thromboembolic events and malignancies. Abstract Background Atopic dermatitis (
Christopher G. Bunick +13 more
wiley +1 more source
Clinical Patterns of Osteoarticular, Bone Marrow and Urogenital Paracoccidioidomycosis
ABSTRACT Background Paracoccidioidomycosis (PCM) is an endemic systemic mycosis in Latin America, classically characterized by pulmonary, mucosal and lymphatic involvement. Extrapulmonary manifestations affecting uncommon organs remain poorly characterized and may contribute to diagnostic delay and adverse outcomes. Methods We conducted a retrospective
Wdson Luis Lima Kruschewsky +7 more
wiley +1 more source
A Rare Case of Central Nervous System Tuberculosis
Ravish Parekh +2 more
doaj +1 more source
Characteristic array of imaging markers in central nervous system tuberculosis
Shambaditya Das +4 more
doaj +1 more source

